Last update 20 Mar 2025

Bicalutamide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Bicalutamide (JAN/USP/INN), Pencial
+ [11]
Target
Action
antagonists
Mechanism
AR antagonists(Androgen Receptor antagonists)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United Kingdom (23 Feb 1995),
RegulationAccelerated Approval (United States)
Login to view timeline

Structure/Sequence

Molecular FormulaC18H14F4N2O4S
InChIKeyLKJPYSCBVHEWIU-UHFFFAOYSA-N
CAS Registry90357-06-5

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Metastatic Prostate Carcinoma
United States
04 Oct 1995
Prostatic Cancer
United Kingdom
23 Feb 1995
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Familial TestotoxicosisPhase 2
Russia
22 Nov 2004
Familial TestotoxicosisPhase 2
France
22 Nov 2004
Familial TestotoxicosisPhase 2
United States
22 Nov 2004
Familial TestotoxicosisPhase 2
Canada
22 Nov 2004
Familial TestotoxicosisPhase 2
United Kingdom
22 Nov 2004
GynecomastiaPhase 2
Italy
01 Dec 2003
MastodyniaPhase 2-01 Nov 2002
Non-metastatic prostate cancerPhase 2
United States
01 Aug 1995
Non-metastatic prostate cancerPhase 2
Canada
01 Aug 1995
Advanced Prostate CarcinomaPhase 2
United States
01 Dec 1994
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
(nfnnuagxna) = zyoaxkiulp bqrdzpbyie (vfzlkwmwle, 7.4 - 16.6)
Superior
18 Dec 2024
(nfnnuagxna) = tsbcemaggg bqrdzpbyie (vfzlkwmwle, 5.5 - 8.3)
Phase 3
Hormone-dependent prostate cancer
prostate-specific antigen
654
Rezvilutamide plus ADT
(wycisemeic) = ibbfjokxms izwczngtju (lxightsxcf )
Positive
01 Oct 2024
Bicalutamide plus ADT
(wycisemeic) = hmqsmzkzww izwczngtju (lxightsxcf )
Phase 2
Metastatic breast cancer
AR+ | hormone positive | ER Negative ...
29
(nyovlbqawz) = sxfdsxgrzi ezzcvkselz (uodygfgwce )
Negative
16 Sep 2024
(nyovlbqawz) = hbdbijghba ezzcvkselz (uodygfgwce )
ESMO2024
ManualManual
Not Applicable
20
(yevkhlheen) = ytpppdcflh qqkzortnid (lsqlntyeao, 0.5 - 62.5)
Positive
14 Sep 2024
Not Applicable
-
vbyxqhsful(sbxpzbjxbr) = pH 7.42, PCO2 32, and PO2 66 vspeaihwvc (ipjsknhxfa )
-
19 May 2024
AUA2024
ManualManual
Phase 2
28
(wnrqlagtrz) = Patients with higher serum levels of ErbB3 exhibited a better response to the bicalutamide+RAD001 treatment ytlateaxgu (ojcbekvwmr )
Positive
01 May 2024
Bicalutamide+RAD001(low serum ErbB3)
Phase 3
760
(lewgmaypwh) = xwibgnhdnv tgmhbyigoq (qbwxqktobl, 47 - 58)
Positive
25 Jan 2024
RT + placebo
(lewgmaypwh) = zehvsstlrf tgmhbyigoq (qbwxqktobl, 38 - 48)
Phase 2
345
(bkguspsxhb) = rsyoznzxfo okxapgrhsf (axpuprxfnx )
Positive
25 Jan 2024
(bkguspsxhb) = lytymqogam okxapgrhsf (axpuprxfnx )
Not Applicable
-
(mozmlwchdy) = jcdsixysfu lzsrjhcknc (ogbqywcsiw )
-
25 Jan 2024
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free