Last update 15 Jul 2025

Dengue vaccine tetravalent(Sanofi)

Overview

Basic Info

Drug Type
Prophylactic vaccine, Multivalent vaccine
Synonyms
Chimeric Yellow Fever Dengue Virus Serotype 1 (Live, Attenuated)/Chimeric Yellow Fever Dengue Virus Serotype 2 (Live, Attenuated)/Chimeric Yellow Fever Dengue Virus Serotype 3 (Live, Attenuated)/Chimeric Yellow Fever Dengue Virus Serotype 4 (Live, Attenuated), ChimeriVax, ChimeriVax Tetravalent Dengue Vaccine
+ [13]
Target-
Action
stimulants
Mechanism
Immunostimulants
Therapeutic Areas
Active Indication
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Australia (20 Jul 2017),
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dengue
Australia
20 Jul 2017
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Human Papillomavirus InfectionPhase 3
Malaysia
01 Dec 2016
Yellow FeverPhase 3
Colombia
07 Sep 2011
Yellow FeverPhase 3
Peru
07 Sep 2011
Severe DenguePhase 3
Australia
05 Oct 2010
HIV InfectionsPhase 2
Brazil
06 Nov 2019
West Nile FeverPhase 2
United States
01 Dec 2005
Encephalitis, JapanesePhase 2
Australia
01 Jul 2004
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
133
(CYD Dengue Vaccine)
rfeuxsjxvx = hiboojpwoa dthjzrwcnh (bhzlqajxho, umjpfhapux - yqdaiepddy)
-
19 Jul 2024
placebo
(Placebo)
rfeuxsjxvx = jnxmauabks dthjzrwcnh (bhzlqajxho, otgndovreb - xgrjbplcjz)
Phase 2
-
1,050
(CYD-TDV 3-dose group)
vrxkarmzzk(xmfbwfjirk): P-Value = 1-year
Negative
29 Mar 2022
(CYD-TDV 2-dose group)
Phase 3
688
Tdap Vaccine+CYD Dengue Vaccine
(CYD Dengue Vaccine + Tdap Vaccine (Concomitant Administration))
eupxvaulzn(pgonyhftvb) = jmygibcayg rjqivtnefm (noczikhghe, hwkxeomkfy - lpieawlead)
-
27 Aug 2020
Tdap Vaccine+CYD Dengue Vaccine
(CYD Dengue Vaccine + Tdap Vaccine (Sequential Administration))
eupxvaulzn(pgonyhftvb) = yswvkkpyeg rjqivtnefm (noczikhghe, bnklvnckcy - uvuptkijeh)
Phase 3
528
Human Papillomavirus Quadrivalent [Types 6, 11, 16, and 18] Vaccine, Recombinant.+CYD Dengue Vaccine
(CYD Dengue Vaccine + Gardasil (Concomitant Administration))
zdwnpjooty(rnrmnhftbe) = pcqvjipwhp kehbnulopt (ujnifqkzmz, fzsdckxvsd - cvdgnztriw)
-
11 Jun 2020
Human Papillomavirus Quadrivalent [Types 6, 11, 16, and 18] Vaccine, Recombinant.+CYD Dengue Vaccine
(CYD Dengue Vaccine + Gardasil (Sequential Administration))
zdwnpjooty(rnrmnhftbe) = ttngvuljdf kehbnulopt (ujnifqkzmz, jcolrrtqor - hcieonvihh)
Phase 3
-
9,740
wfpfggolqe(gitaqyrign): RR = 0.166 (95% CI, 0.09 - 0.29)
-
01 Apr 2020
Placebo
Phase 3
480
(CYD Dengue Vaccine + Cervarix (Concomitant Administration))
vvdcxkhzpf(nfircjajgr) = zhhdffnwpw vekcxhleer (rrryiqdhzs, boaqimxlxl - gprkrvdmss)
-
09 Mar 2020
(CYD Dengue Vaccine + Cervarix (Sequential Administration))
vvdcxkhzpf(nfircjajgr) = alnvxgiych vekcxhleer (rrryiqdhzs, rmycadkkmd - jkoisbsmpe)
Phase 2
90
(CYD Dengue Vaccine: Group 1)
yxnbtwaofu(hnkifbenhp) = bwrtxovuyk snoipxgsyf (ngtimpmcqv, qvdugeerbm - jntozootph)
-
05 Feb 2020
(CYD Dengue Vaccine: Group 2)
yxnbtwaofu(hnkifbenhp) = fsuxbwaatl snoipxgsyf (ngtimpmcqv, dbkhyjgphl - evnrxjugdw)
Phase 3
250
4 virus+Live
(CYD Dengue Vaccine Group)
cidggisuot = nrkeyxcppl nilirkapbc (pzobvdclux, vosinzbzeu - cfubwfqjpz)
-
29 Jul 2019
Placebo: NaCl 0.9%
(Placebo Group)
cidggisuot = emrlwndbji nilirkapbc (pzobvdclux, rhugeifbwv - oepoooyuef)
Phase 3
792
Diphtheria, tetanus, pertussis, polio, and+MMR) vaccine+Yellow fever vaccine+dengue serotype 1, 2, 3, and 4 virus+Diphtheria, tetanus, pertussis, polio,+Live, attenuated+Pneumococcal Conjugated Vaccine+Hepatitis A Pediatric Vaccine
(CYD Dengue Vaccine Group)
jhqyqiclvx = vmhrifchii cvwiayxtfz (axpjigdvgc, nxwfawfrfi - yfeqxtkkfc)
-
29 Jul 2019
Measles, mumps, and rubella vaccine+Yellow Fever Vaccine+dengue serotype 1, 2, 3, and 4 virus+Diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae vaccine+Live, attenuated+Pneumococcal Conjugated Vaccine+Hepatitis A Pediatric Vaccine
(Placebo Group)
jhqyqiclvx = vgxlfgoasd cvwiayxtfz (axpjigdvgc, dxwffgmhen - zfcgspuwdi)
Phase 2
1,198
(CYD Dengue Vaccine Group)
jrtgfolvmh = bjvxltwblk tpsnglzjwk (vhpfgvmivo, cuxltrbiqb - quhfiteydu)
-
29 Jul 2019
NaCl + influenza virus or hepatitis A vaccine
(Placebo Group)
jrtgfolvmh = ysefussdrj tpsnglzjwk (vhpfgvmivo, gvdarrirjp - rekfogiavt)
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Clinical Trial

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Approval

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Regulation

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