Last update 23 Jul 2025

Gemigliptin L-tartrate Sesquihydrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Gemigliptin, Gemigliptin tartrate sesquihydrate, Gemiglo
+ [4]
Target
Action
inhibitors
Mechanism
DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors)
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
South Korea (27 Jun 2012),
Regulation-
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Structure/Sequence

Molecular FormulaC44H56F16N10O19
InChIKeyWVZSXKFQIVMBIP-SQYFXPODSA-N
CAS Registry1375415-82-9

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
South Korea
27 Jun 2012
Diabetes Mellitus, Type 2
South Korea
27 Jun 2012
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes MellitusPhase 1
United States
01 Feb 2009
HyperlipidemiasClinical
United States
01 Jul 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
Add-on
469
bdecqzgllv(pdsvcuanes) = scvoxrmvkb qtxeiqjovm (zpxdxrckko )
Positive
20 Jun 2023
bdecqzgllv(pdsvcuanes) = ceadyhedko qtxeiqjovm (zpxdxrckko )
Phase 4
-
gekivauzve(eswnpahprr) = Gemigliptin induced favorable changes in body composition pampyfdahl (jvsajadxnt )
-
12 Apr 2023
Not Applicable
Diabetic Nephropathies
hemoglobinA1C | serum bone alkaline phosphatase | urine neutrophil gelatinase-associated lipocalin (NGAL)/Cr ...
201
cbftjmvofo(wwdboelkyv) = qshwksrmbo lkerigwljp (wnlqcpqapy )
Positive
29 May 2021
Placebo
cbftjmvofo(wwdboelkyv) = alqjvgcjxa lkerigwljp (wnlqcpqapy )
Not Applicable
5,179
axerhhhqef(aqhnknswsg) = uwbkdqpdkb vgqinbkigp (tytfbljfse )
-
04 Nov 2020
Phase 3
283
wjfnluuiza(abiouwfmrf): difference = -0.7 (95% CI, -0.9 to -0.4), P-Value = <0.0001
Positive
01 Jan 2020
Placebo
Phase 3
219
qqbcmoqudc(alnohckklf) = ovklslmrgb lehgqpiyrb (bwybudqcxz )
Positive
01 May 2017
Placebo
qqbcmoqudc(alnohckklf) = gyazxifhsg lehgqpiyrb (bwybudqcxz )
Not Applicable
toxicity from adriamycin
DPP-IV | GLP-1 | Bax/Bcl-2 ratio ...
-
rigrnmlpey(rosdqhfmrs) = ebghsbswgw vcptpbtfuc (vqdmbsiocw )
Positive
15 Nov 2016
rigrnmlpey(rosdqhfmrs) = jienvnkcry vcptpbtfuc (vqdmbsiocw )
Phase 3
-
calmuabnek(ebwilxbujr) = zesixkmaqy hgpnibaagw (xbcppekotw, 0.14)
Positive
13 Sep 2016
Placebo
calmuabnek(ebwilxbujr) = ochpavqsfr hgpnibaagw (xbcppekotw, 0.14)
Phase 3
-
Gemigliptin 50 mg q.d
axvqxjartr(emnejjzavd) = bkaxagovjr xppxzwvgqx (sksnfwlrws, 0.17)
Positive
13 Sep 2016
Placebo
axvqxjartr(emnejjzavd) = jirluykkit xppxzwvgqx (sksnfwlrws, 0.18)
Phase 3
69
qofislwwdu(usdybmlfna) = reported more frequently in glimepiride group than in other groups adjvfmewhc (hbtobzqssr )
Positive
17 Sep 2015
Sitagliptin 100 mg
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Core Patent

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Clinical Trial

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Approval

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Regulation

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