Last update 30 Mar 2025

Rubitecan

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
9-NC, 9-nitro-(20S)-camptothecin, 9-Nitro-20(S)-camptothecin
+ [9]
Target
Action
inhibitors
Mechanism
TOP1 inhibitors(DNA topoisomerase I inhibitors)
Therapeutic Areas
Active Organization
Drug Highest PhasePhase 1
First Approval Date-
RegulationOrphan Drug (United States), Orphan Drug (European Union)
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Structure/Sequence

Molecular FormulaC20H15N3O6
InChIKeyVHXNKPBCCMUMSW-FQEVSTJZSA-N
CAS Registry91421-42-0

External Link

KEGGWikiATCDrug Bank
D04031Rubitecan-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic carcinoma non-resectablePhase 3
United States
01 Feb 2005
Pancreatic adenocarcinomaPhase 3
United States
01 Mar 1999
Pancreatic CancerPhase 3
United States
01 Nov 1998
Advanced gastric carcinomaPhase 2
United States
01 Apr 2000
Esophageal CarcinomaPhase 2
United States
01 Apr 2000
Advanced Colorectal AdenocarcinomaPhase 2
United States
01 Sep 1999
Metastatic breast cancerPhase 2
United States
01 Sep 1999
Gastrointestinal Stromal TumorsPhase 2
United States
01 Jun 1999
Metastatic Soft Tissue SarcomaPhase 2
United States
01 Jun 1999
Small intestine carcinomaPhase 2
United States
01 Jun 1999
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
24
gghzvsiyly(chilxwftkz) = duyxkfkjlg xufgukzvkc (enyedrlsxn )
-
15 Jul 2004
Phase 3
409
opciuyevrv(vzzjnroloq) = ysrtvewdyh tdcwkyhuww (npprfovwzl )
-
15 Jul 2004
(Best Choice (BC))
opciuyevrv(vzzjnroloq) = tydwvwvnel tdcwkyhuww (npprfovwzl )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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