Drug Type Small molecule drug |
Synonyms 9-NC, 9-nitro-(20S)-camptothecin, 9-Nitro-20(S)-camptothecin + [9] |
Target |
Action inhibitors |
Mechanism TOP1 inhibitors(DNA topoisomerase I inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
RegulationOrphan Drug (United States), Orphan Drug (European Union) |
Molecular FormulaC20H15N3O6 |
InChIKeyVHXNKPBCCMUMSW-FQEVSTJZSA-N |
CAS Registry91421-42-0 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Pancreatic carcinoma non-resectable | Phase 3 | United States | 01 Feb 2005 | |
Pancreatic adenocarcinoma | Phase 3 | United States | 01 Mar 1999 | |
Pancreatic Cancer | Phase 3 | United States | 01 Nov 1998 | |
Advanced gastric carcinoma | Phase 2 | United States | 01 Apr 2000 | |
Esophageal Carcinoma | Phase 2 | United States | 01 Apr 2000 | |
Advanced Colorectal Adenocarcinoma | Phase 2 | United States | 01 Sep 1999 | |
Metastatic breast cancer | Phase 2 | United States | 01 Sep 1999 | |
Gastrointestinal Stromal Tumors | Phase 2 | United States | 01 Jun 1999 | |
Metastatic Soft Tissue Sarcoma | Phase 2 | United States | 01 Jun 1999 | |
Small intestine carcinoma | Phase 2 | United States | 01 Jun 1999 |
Phase 1 | 24 | kbkshcxgin(jmoswdvsyl) = auvhokdlpb brrzimukte (mqjkcvnkxm ) View more | - | 15 Jul 2004 | |||
Phase 3 | 409 | lbhlolbjnz(fixesbfsyk) = daypjyimsn nlwfpsajlm (emcbciodyd ) View more | - | 15 Jul 2004 | |||
(Best Choice (BC)) | lbhlolbjnz(fixesbfsyk) = gqkyfhymff nlwfpsajlm (emcbciodyd ) View more |