Drug Type Small molecule drug |
Synonyms 9-NC, 9-nitro-(20S)-camptothecin, 9-Nitro-20(S)-camptothecin + [9] |
Target |
Action inhibitors |
Mechanism TOP1 inhibitors(DNA topoisomerase I inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
RegulationOrphan Drug (United States), Orphan Drug (European Union) |
Molecular FormulaC20H15N3O6 |
InChIKeyVHXNKPBCCMUMSW-FQEVSTJZSA-N |
CAS Registry91421-42-0 |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Pancreatic carcinoma non-resectable | Phase 3 | United States | 01 Feb 2005 | |
| Pancreatic adenocarcinoma | Phase 3 | United States | 01 Mar 1999 | |
| Pancreatic Cancer | Phase 3 | United States | 01 Nov 1998 | |
| Advanced gastric carcinoma | Phase 2 | United States | 01 Apr 2000 | |
| Esophageal Carcinoma | Phase 2 | United States | 01 Apr 2000 | |
| Advanced Colorectal Adenocarcinoma | Phase 2 | United States | 01 Sep 1999 | |
| Metastatic breast cancer | Phase 2 | United States | 01 Sep 1999 | |
| Gastrointestinal Stromal Tumors | Phase 2 | United States | 01 Jun 1999 | |
| Metastatic Soft Tissue Sarcoma | Phase 2 | United States | 01 Jun 1999 | |
| Small intestine carcinoma | Phase 2 | United States | 01 Jun 1999 |
Phase 2 | 35 | zdkwghliag(odnpennryi) = blxhruxcua gosmbghmsp (bporgcvlvu, 5 - 12) View more | Negative | 31 Oct 2004 | |||
Phase 3 | 409 | qziirnbyee(wtiwywptpq) = xhnylipofe ywnorfuwik (ghyvxulkqg ) View more | - | 15 Jul 2004 | |||
(Best Choice (BC)) | qziirnbyee(wtiwywptpq) = ppstskjxqz ywnorfuwik (ghyvxulkqg ) View more | ||||||
Phase 1 | 24 | ppzwrrebqo(qehrinpiav) = vntplgxhww txouivdqwa (ligrvhsnac ) View more | - | 15 Jul 2004 |





