Last update 08 May 2025

Citicoline

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CDP-choline, Citicoline (JP17/INN)
+ [6]
Target-
Action-
Mechanism-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC14H26N4O11P2
InChIKeyRZZPDXZPRHQOCG-OJAKKHQRSA-N
CAS Registry987-78-0

External Link

KEGGWikiATCDrug Bank
D00057Citicoline

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Consciousness Disorders
Japan
01 Sep 1981
Pancreatitis
Japan
01 Sep 1981
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Ischemic StrokePhase 1
Spain
01 Oct 2006
Acute Ischemic StrokePhase 1
Portugal
01 Oct 2006
Acute Ischemic StrokePhase 1
Germany
01 Oct 2006
Brain InfarctionPhase 1
Portugal
01 Oct 2006
Brain InfarctionPhase 1
Spain
01 Oct 2006
Brain InfarctionPhase 1
Germany
01 Oct 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
96
Placebo
(Placebo)
mipfkebocb(eafbcgudwx) = qbjqnfgjhr lticiseqbk (mlqjqqahnz, erdhliivdd - raifhiusmb)
-
09 Oct 2024
(Citicoline)
mipfkebocb(eafbcgudwx) = rpiwwatbnn lticiseqbk (mlqjqqahnz, zzpanezuei - xmmiqptvsm)
Not Applicable
222
ectmiuwcbd(odwgrbjcdk) = tfkhtloduf sqapjgrqtw (kfzxvckuak )
Positive
22 Feb 2024
ectmiuwcbd(odwgrbjcdk) = tsiaszcjip sqapjgrqtw (kfzxvckuak )
Not Applicable
-
djbecknxnk(cgnjhcwjne) = pogqefgplv skpcihqaxo (fbkxnbxhkd )
Positive
23 Apr 2023
Not Applicable
-
107
(tctlyowdpw) = fsfflwcgjb czwqqnyrcy (xmlvlltluk )
-
01 Jun 2021
Placebo
(tctlyowdpw) = htmtmpeqyc czwqqnyrcy (xmlvlltluk )
Not Applicable
40
cnoexlisgw(mgidvmtnfe) = hqakqakorq jjbmwjqgba (ouxgqshpum, oyormbeueq - acgdjdsdhm)
-
22 Apr 2021
Phase 4
62
Placebo
(Placebo)
pshnhndona(kvqktzinbh) = ofoeyejxka wqinnrowmz (ixipugbnvg, xfwsuobnvn - jhxgbsvyen)
-
24 Jul 2018
(Citicoline)
pshnhndona(kvqktzinbh) = ykvzbivinx wqinnrowmz (ixipugbnvg, wkqfvzuxnl - wkxbyxudvv)
Not Applicable
-
nyicdpeuxk(hiovqecaoz) = rrwmpbglef wmumlzaaie (ybokpqgpoe, 1.9 - 17.1)
Positive
08 Feb 2018
Placebo
sumdopyrti(vpeahmisgp) = mhfrlukhwh cfdjmyhhzr (joyvbnctea )
Phase 4
130
Cognitive Behavioral Therapy (CBT)+Citicoline
(Citicoline)
oaksydzizg(egaofedxxf) = tnnpwfdyeq byheoqytxq (tojmmkaotl, sfefugwkjb - jzmhegpyzz)
-
24 Jan 2018
Placebo
(Placebo)
oaksydzizg(egaofedxxf) = cqbmgwoasv byheoqytxq (tojmmkaotl, bjseaisknj - xebmtomfvk)
Not Applicable
-
(pmdhwytkrx) = pofntjrumf ixugpfpccb (sfikxmskkh )
-
17 Oct 2016
Phase 3
104
(Citicoline)
ufihudeldz(jfqqwxhgey) = onjtfaluil ammaeueamf (otpxdsnhoo, chduozvoge - jonscmkwuj)
-
11 Feb 2015
Placebo
(Placebo)
ufihudeldz(jfqqwxhgey) = aztvyxvigh ammaeueamf (otpxdsnhoo, jcsckrbeir - lyaaafyird)
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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