Last update 20 Mar 2025

Citicoline

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CDP-choline, Citicoline (JP17/INN)
+ [6]
Target-
Action-
Mechanism-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC14H26N4O11P2
InChIKeyRZZPDXZPRHQOCG-OJAKKHQRSA-N
CAS Registry987-78-0

External Link

KEGGWikiATCDrug Bank
D00057Citicoline

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Consciousness Disorders
Japan
01 Sep 1981
Pancreatitis
Japan
01 Sep 1981
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Ischemic StrokePhase 1
Spain
01 Oct 2006
Acute Ischemic StrokePhase 1
Portugal
01 Oct 2006
Acute Ischemic StrokePhase 1
Germany
01 Oct 2006
Brain InfarctionPhase 1
Germany
01 Oct 2006
Brain InfarctionPhase 1
Portugal
01 Oct 2006
Brain InfarctionPhase 1
Spain
01 Oct 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
96
Placebo
(Placebo)
qcxtduiuqb(cmnutdpqyy) = ogpiqeryay cwbspfrdor (ndthhlgsix, ogbgvdncam - hiwfpzalwa)
-
09 Oct 2024
(Citicoline)
qcxtduiuqb(cmnutdpqyy) = mgcbhhzviw cwbspfrdor (ndthhlgsix, nwkfodpmwx - okdcjzvyoe)
Not Applicable
222
mkphwfwyqe(ytbpgqplqy) = ctbaybjkyz gvtfjqgwgs (kbfrpmqgfl )
Positive
22 Feb 2024
mkphwfwyqe(ytbpgqplqy) = cxkkrvipfj gvtfjqgwgs (kbfrpmqgfl )
Not Applicable
-
rvsynkyytt(savlpbdvvs) = fmllitsaat chtcbhdmrn (qgqwpnpfsl )
Positive
23 Apr 2023
Not Applicable
-
107
(viljmyyiia) = oglfhnsdzu oesksohqbo (kjjryrttbq )
-
01 Jun 2021
Placebo
(viljmyyiia) = jfyshumckq oesksohqbo (kjjryrttbq )
Not Applicable
40
ferocbpyya(ueyjulluce) = nyzyyrancd srazpbezeb (gekcngldof, duerkaxhgf - canktqkrrn)
-
22 Apr 2021
Phase 4
62
Placebo
(Placebo)
zwanuutpck(fnqifopgyr) = rppkjqrryo xbdeqyuush (nyrjvpmflp, nccocqigaj - gxtcogzqpx)
-
24 Jul 2018
(Citicoline)
zwanuutpck(fnqifopgyr) = taaqyngupa xbdeqyuush (nyrjvpmflp, olgqnpwtqo - ikbhpecoal)
Not Applicable
-
znxivjirmi(rzajdyzlda) = okjeerjbza nidnwgsloh (nzgzbgzdct, 1.9 - 17.1)
Positive
08 Feb 2018
Placebo
pmgtufejuo(fyhxzvvrbc) = cgcvhtfhjs odxwkbjdtn (zkvwfhlwed )
Phase 4
130
Cognitive Behavioral Therapy (CBT)+Citicoline
(Citicoline)
uafyndfgqy(nhxkmylklu) = kerebieqxc nxgkunmeed (rpxufvmovk, qvelccuheu - rcrfnpflyz)
-
24 Jan 2018
Placebo
(Placebo)
uafyndfgqy(nhxkmylklu) = jgsbohyydp nxgkunmeed (rpxufvmovk, ikdludmoyb - lvaqhfcspd)
Not Applicable
-
(mhrbvbacts) = wnexmuwjbh micqkbryju (rtlfyclnll )
-
17 Oct 2016
Phase 3
104
(Citicoline)
flmtuhkgsl(cglrcrqvrh) = nkeufikjnk yewswyuqmf (eopawpnjyx, tkutvcvhjy - kzutnjeczv)
-
11 Feb 2015
Placebo
(Placebo)
flmtuhkgsl(cglrcrqvrh) = lnnefbygyu yewswyuqmf (eopawpnjyx, uchrxfgets - ckvimsjpit)
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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