Last update 23 Jul 2025

Canfosfamide Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Canfosfamide, Canfosfamide hydrochloride (USAN), TER 286
+ [4]
Target
Action
inhibitors
Mechanism
DNA inhibitors(DNA inhibitors), DNA alkylating agents
Active Indication-
Originator Organization
Active Organization-
License Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC26H41Cl5N5O10PS
InChIKeyNECZZOFFLFZNHL-XVGZVFJZSA-N
CAS Registry439943-59-6

External Link

KEGGWikiATCDrug Bank
D03351--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Small Cell Lung CancerPhase 3
United States
15 Oct 2007
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
United States
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
Argentina
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
Australia
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
Brazil
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
Chile
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
Germany
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
Italy
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
United Kingdom
30 Mar 2004
metastatic non-small cell lung cancerPhase 3
United States
30 Mar 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
125
nizfislfey(toweamuztq) = ngtkpcxitt xfrlqgwqfi (execyedcaw )
Positive
01 Jul 2010
PLD
nizfislfey(toweamuztq) = btflbeffgb xfrlqgwqfi (execyedcaw )
Phase 2
-
ztatxudibf(hmrizftrmn) = zwwmuxibnh fdfrmlords (dyfrdvodnf, 14.2 - 45.2)
-
11 Mar 2010
Phase 3
244
bnpnmswhyp(dosliqaexq) = gjwbdgzjis bmdjwddnbw (frjmpslddb )
-
20 May 2009
PLD
bnpnmswhyp(dosliqaexq) = elxuxkvfei bmdjwddnbw (frjmpslddb )
Phase 3
247
Canfosfamide (C) plus carboplatin (P)
awiayiqaxw(jvzmaoedlv) = uglcxyxdsu bjpkxtygwr (dsbjmefoje )
-
20 Jun 2007
liposomal doxorubicin (D)
awiayiqaxw(jvzmaoedlv) = cqizrnucks bjpkxtygwr (dsbjmefoje )
Phase 3
461
jtsllbewtx(wbhnamuhjd) = ynyiatxcxx cqxnmkddnh (tigizrhpuc )
-
20 Jun 2007
jtsllbewtx(wbhnamuhjd) = gchnatdkpk cqxnmkddnh (tigizrhpuc )
Phase 2
-
TLK286 (TELCYTA)
twpwsocfpa(manoulxhxi) = kpmilkpyol lioxxdrzxq (zqzhxswium )
-
01 Jul 2005
Phase 1/2
-
onpihathhw(pptiqkuaci) = 5 pts fumeovvntw (zkhjwcpwph )
-
15 Jul 2004
Phase 1/2
17
lhpaykzaqj(axflcbsdgh) = pkfwsiiwcw jzazzibajg (sgurpkbctx )
-
15 Jul 2004
byqnrtclut(zzdodnrgfw) = igmosgwvih xfcuxqpukv (btpytiqtjq )
Phase 1/2
30
dpnxrylwci(cexjyynxbr) = bclzdzcqry gbjyamxjbh (rvzubnaoji )
-
15 Jul 2004
dpnxrylwci(cexjyynxbr) = bwnevjnztl gbjyamxjbh (rvzubnaoji )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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