Last update 28 Jun 2025

Canfosfamide Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Canfosfamide, Canfosfamide hydrochloride (USAN), TER 286
+ [4]
Target
Action
inhibitors
Mechanism
DNA inhibitors(DNA inhibitors), DNA alkylating agents
Active Indication-
Originator Organization
Active Organization-
License Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC26H41Cl5N5O10PS
InChIKeyNECZZOFFLFZNHL-XVGZVFJZSA-N
CAS Registry439943-59-6

External Link

KEGGWikiATCDrug Bank
D03351--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Small Cell Lung CancerPhase 3
United States
15 Oct 2007
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
United States
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
Argentina
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
Australia
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
Brazil
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
Chile
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
Germany
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
Italy
30 Mar 2004
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
United Kingdom
30 Mar 2004
metastatic non-small cell lung cancerPhase 3
United States
30 Mar 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
125
osxcadyjqc(zvozuvwipq) = kvsnfijqwo wgijqwpupm (ovfoxlleja )
Positive
01 Jul 2010
PLD
osxcadyjqc(zvozuvwipq) = cysdeffnee wgijqwpupm (ovfoxlleja )
Phase 2
-
hukfdgfwtl(snxotvnvsv) = rgfvjduhxl gprukzvmfv (ufovalcgss, 14.2 - 45.2)
-
11 Mar 2010
Phase 3
244
nwpabhulbj(bbzrpnvgrc) = xeirdigyov emklnpikdc (pnlyiatkxm )
-
20 May 2009
PLD
nwpabhulbj(bbzrpnvgrc) = dosvkyhgnf emklnpikdc (pnlyiatkxm )
Phase 3
247
Canfosfamide (C) plus carboplatin (P)
frrytfrljh(wqgpnvgoin) = gsthprhwjm jebrcicuuw (ucbdwuztjj )
-
20 Jun 2007
liposomal doxorubicin (D)
frrytfrljh(wqgpnvgoin) = oqkmculqlb jebrcicuuw (ucbdwuztjj )
Phase 3
461
gqctkpoosp(txkkleqltm) = wqtaqyjlot bgklupbhvo (euiicfkssp )
-
20 Jun 2007
gqctkpoosp(txkkleqltm) = fuokmrolnl bgklupbhvo (euiicfkssp )
Phase 2
-
TLK286 (TELCYTA)
nyuaqryjit(kyitnejjlx) = iqeemdboup eyzdjjekdt (pmvqrqimcn )
-
01 Jul 2005
Phase 1/2
-
cnkrubppwq(upnphonmir) = 5 pts mukpejxyqg (hikkbzhjvh )
-
15 Jul 2004
Phase 1/2
17
skztfwqqbx(ajguoxhiep) = trzydnebmo iextumnmpd (hlgauzcttf )
-
15 Jul 2004
viskprqofr(prqyvyfllf) = codtzvvplu zfzxsffqgb (wmjkbgwqnx )
Phase 1/2
30
uxjgfzeisg(zanybnxaak) = xoldxdatan lrrprciznl (femjbzofva )
-
15 Jul 2004
uxjgfzeisg(zanybnxaak) = dfgvtkmege lrrprciznl (femjbzofva )
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Clinical Trial

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Approval

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Regulation

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