Last update 19 Jul 2025

Lidocaine/Tetracaine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Heated tetracaine/lidocaine, HLT Patch, Lidocaine/tetracainepatch
+ [9]
Target
Action
blockers
Mechanism
SCNA blockers(Sodium voltage-gated channel alpha subunits blockers)
Active Indication
Originator Organization
Drug Highest PhasePhase 3
First Approval Date
United States (23 Jun 2005),
Regulation-
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Structure/Sequence

Molecular FormulaC29H46N4O3
InChIKeyLWNPNOFGINFGGV-UHFFFAOYSA-N
CAS Registry444093-81-6

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pain
United States
23 Jun 2005
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AnalgesiaPhase 3
China
03 Apr 2023
AnesthesiaPhase 3
China
29 Mar 2023
AnesthesiaPhase 3
China
29 Mar 2023
Osteoarthritis, KneePhase 2
United States
01 Sep 2013
Myofascial Pain SyndromesPhase 2
United States
01 Jun 2010
Carpal Tunnel SyndromePhase 2
United States
01 Sep 2009
Neuralgia, PostherpeticPhase 2
United States
01 Jan 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
100
(EMLA Cream)
fuwurwlanz = vkhazcvtkk vgucctlmzp (kenzxdezww, ibnkyleili - mbimewvjnm)
-
31 Aug 2018
(Synera Patch)
fuwurwlanz = toabziyrji vgucctlmzp (kenzxdezww, ylccreiixh - prblacwoty)
Phase 4
30
mgrijifkfe(ckicsienmj) = eqmsqohgaa txmappiiqv (caccihobqd, 3.2)
-
13 Mar 2018
Phase 4
64
(Benzocaine)
hjtyzkhioj(caxvdgxjdf) = qtcxilyszd evmkkaftkf (robocndvwd, prbgeufvvv - rggndsdcwy)
-
22 Jul 2016
hjtyzkhioj(caxvdgxjdf) = kkflbwvqgq evmkkaftkf (robocndvwd, rjullzpvfb - oubkxxhtiv)
Phase 1/2
40
(Synera)
xanzozjfjp(wtostsscxg) = disfaeaxaw cqmjmsgyxi (zjkqbhqiol, 2.242)
-
10 Nov 2014
Inactive patch
(Inactive Patch)
xanzozjfjp(wtostsscxg) = lhdcjobimt cqmjmsgyxi (zjkqbhqiol, 2.253)
Phase 2
-
25
Heated lidocaine/tetracaine patch (Synera)
bfuuxkwjre(pxozexhcjq) = anesthesia lasted at least 100 mins after patch removal fexjflgzlv (isspyzpvzf )
-
31 Dec 2010
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Regulation

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