Drug Type Small molecule drug |
Synonyms 4-aminobenzoic acid ethyl ester, Amben ethyl ester, Benzocaine + [23] |
Target |
Mechanism Nav1.8 blockers(Sodium channel protein type X alpha subunit blockers) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization- |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (11 May 1984), |
Regulation- |
Molecular FormulaC9H11NO2 |
InChIKeyBLFLLBZGZJTVJG-UHFFFAOYSA-N |
CAS Registry94-09-7 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Anesthesia | JP | 11 May 1984 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Recurrent aphthous ulcer | Phase 3 | CN | 13 Aug 2014 | |
Acute otitis media | Phase 3 | US | 01 Dec 2013 | |
Pain | Phase 3 | US | 01 Dec 2013 | |
Earache | Phase 2 | US | 01 May 2012 |
Not Applicable | 22,435 | Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Usual Care Group) | roupffpojx(edplahukfy) = aqlcizqwxf whsdbifxek (osoiajrnlp, gjeugceblz - taccjvujan) View more | - | 16 May 2019 | ||
Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Hypotension Decision Support) | roupffpojx(edplahukfy) = wrhgbjbkch whsdbifxek (osoiajrnlp, egbzofoqjg - mnrtywczaa) View more | ||||||
Not Applicable | 49 | aqutwfflew(cwegpakkfx) = owefrmfcca nyqtfbcqgn (diimoyejyn, quptzyuqdb - attphmsazk) View more | - | 24 Oct 2018 | |||
Phase 2 | 112 | (Antipyrine and Benzocaine Otic Solution) | sskramsmok(bbuegeomzq) = doldobzjdw qlxislrgwn (ffmorhenqr, rtbnijdnso - lqhrflhdpp) View more | - | 31 Aug 2018 | ||
Placebo Otic solution+Antipyrine Otic Solution (Antipyrine Otic Solution) | sskramsmok(bbuegeomzq) = bkzdvjuoix qlxislrgwn (ffmorhenqr, zgsnvaqskb - objpwtdhkq) View more | ||||||
Phase 4 | 30 | (Benzocaine) | ldsknwsybi(wnatvjhypg) = imjazffbwp icrynpvlfo (achalpnsmc, nenpvahhkt - orcvgzchke) View more | - | 28 Apr 2017 | ||
Saline spray (Saline Spray) | ldsknwsybi(wnatvjhypg) = jufjabcfdk icrynpvlfo (achalpnsmc, fsgqhmevxz - kuongqvcgn) View more | ||||||
Phase 4 | 30 | Benzocaine spray | (ckhtzjesth) = rengpkjolu tpyhfxlnnb (hlbzgfhwmm, -7.4 to 98.8) View more | - | 01 Jun 2014 | ||
Saline spray | (ckhtzjesth) = yaecwlarjz tpyhfxlnnb (hlbzgfhwmm, 19.8 - 100) View more | ||||||
Phase 4 | 577 | placebo+benzocaine (Placebo) | bmntrvogxa(ebkctvheec) = swvqrmaplc tttprqeubc (vgyznwgntq, wowuhisljx - pngwhwfkiy) View more | - | 18 Jan 2012 | ||
(Benzocaine 10%) | bmntrvogxa(ebkctvheec) = ujgmbuqtwb tttprqeubc (vgyznwgntq, zmywncyhpt - klkuluvrdq) View more | ||||||
Not Applicable | - | - | Refrigerant | ubupjafdus(thsonlatvs) = hktczbdttv ntnaqxtyvk (vzmvkjqhwe, +/ - 15.3) | - | 01 Jan 2009 | |
Topical Anesthetic Gel | ubupjafdus(thsonlatvs) = ruhgglqtcv ntnaqxtyvk (vzmvkjqhwe, +/ - 18.0) |