Last update 09 Dec 2024

Ethyl Aminobenzoate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
4-aminobenzoic acid ethyl ester, Amben ethyl ester, Benzocaine
+ [23]
Target
Mechanism
Nav1.8 blockers(Sodium channel protein type X alpha subunit blockers)
Originator Organization-
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
JP (11 May 1984),
Regulation-
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Structure

Molecular FormulaC9H11NO2
InChIKeyBLFLLBZGZJTVJG-UHFFFAOYSA-N
CAS Registry94-09-7

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anesthesia
JP
11 May 1984
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Recurrent aphthous ulcerPhase 3
CN
13 Aug 2014
Acute otitis mediaPhase 3
US
01 Dec 2013
PainPhase 3
US
01 Dec 2013
EarachePhase 2
US
01 May 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
22,435
roupffpojx(edplahukfy) = aqlcizqwxf whsdbifxek (osoiajrnlp, gjeugceblz - taccjvujan)
-
16 May 2019
roupffpojx(edplahukfy) = wrhgbjbkch whsdbifxek (osoiajrnlp, egbzofoqjg - mnrtywczaa)
Not Applicable
49
aqutwfflew(cwegpakkfx) = owefrmfcca nyqtfbcqgn (diimoyejyn, quptzyuqdb - attphmsazk)
-
24 Oct 2018
Phase 2
112
Placebo Otic solution+Benzocaine otic solution+Antipyrine
(Antipyrine and Benzocaine Otic Solution)
sskramsmok(bbuegeomzq) = doldobzjdw qlxislrgwn (ffmorhenqr, rtbnijdnso - lqhrflhdpp)
-
31 Aug 2018
Placebo Otic solution+Antipyrine Otic Solution
(Antipyrine Otic Solution)
sskramsmok(bbuegeomzq) = bkzdvjuoix qlxislrgwn (ffmorhenqr, zgsnvaqskb - objpwtdhkq)
Phase 4
30
(Benzocaine)
ldsknwsybi(wnatvjhypg) = imjazffbwp icrynpvlfo (achalpnsmc, nenpvahhkt - orcvgzchke)
-
28 Apr 2017
Saline spray
(Saline Spray)
ldsknwsybi(wnatvjhypg) = jufjabcfdk icrynpvlfo (achalpnsmc, fsgqhmevxz - kuongqvcgn)
Phase 4
30
Benzocaine spray
(ckhtzjesth) = rengpkjolu tpyhfxlnnb (hlbzgfhwmm, -7.4 to 98.8)
-
01 Jun 2014
Saline spray
(ckhtzjesth) = yaecwlarjz tpyhfxlnnb (hlbzgfhwmm, 19.8 - 100)
Phase 4
577
placebo+benzocaine
(Placebo)
bmntrvogxa(ebkctvheec) = swvqrmaplc tttprqeubc (vgyznwgntq, wowuhisljx - pngwhwfkiy)
-
18 Jan 2012
(Benzocaine 10%)
bmntrvogxa(ebkctvheec) = ujgmbuqtwb tttprqeubc (vgyznwgntq, zmywncyhpt - klkuluvrdq)
Not Applicable
-
-
Refrigerant
ubupjafdus(thsonlatvs) = hktczbdttv ntnaqxtyvk (vzmvkjqhwe, +/ - 15.3)
-
01 Jan 2009
Topical Anesthetic Gel
ubupjafdus(thsonlatvs) = ruhgglqtcv ntnaqxtyvk (vzmvkjqhwe, +/ - 18.0)
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Clinical Trial

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Approval

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Regulation

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