Drug Type Small molecule drug |
Synonyms GSK5458448, HS-10366, MK-3118 + [3] |
Target |
Action inhibitors |
Mechanism 1,3-beta-glucan synthase inhibitors, Cell wall inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization |
Drug Highest PhaseApproved |
First Approval Date United States (01 Jun 2021), |
RegulationPriority Review (United States), Fast Track (United States), Orphan Drug (United States), Qualified Infectious Disease Product (United States), Orphan Drug (European Union) |
Molecular FormulaC50H75N5O11 |
InChIKeyWKIRTJACGBEXBZ-FQGZCCSZSA-N |
CAS Registry1965291-08-0 |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Candidiasis, Vulvovaginal | United States | 01 Jun 2021 |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Candida Auris Infection | Phase 3 | United States | 15 Nov 2017 | |
| Candida Auris Infection | Phase 3 | India | 15 Nov 2017 | |
| Candida Auris Infection | Phase 3 | Pakistan | 15 Nov 2017 | |
| Candida Auris Infection | Phase 3 | South Africa | 15 Nov 2017 | |
| Candidemia | Phase 3 | United States | 15 Nov 2017 | |
| Candidemia | Phase 3 | India | 15 Nov 2017 | |
| Candidemia | Phase 3 | Pakistan | 15 Nov 2017 | |
| Candidemia | Phase 3 | South Africa | 15 Nov 2017 | |
| Aspergillosis, Allergic Bronchopulmonary | Phase 3 | United States | 01 Apr 2017 | |
| Aspergillosis, Allergic Bronchopulmonary | Phase 3 | Austria | 01 Apr 2017 |
Phase 1 | 5 | iedmjbkkql(cuaxxjftgk) = adpnegbpnc whuzcwvgau (tnntamktlo, iokficlnnn - tfjmhpdxrx) View more | - | 08 Aug 2025 | |||
Phase 3 | 233 | ztchuegfrd(bsxsoxpqyx) = axcfxybucc crtofqrdwz (lqyvzxwrrs, dqrrrjpfav - isjwczrqcg) View more | - | 20 Nov 2024 | |||
Phase 3 | 360 | aimgzoigez(mnbwtcmxtq) = aumqnrzlnv yruxgwlecx (laffvltswm ) View more | Positive | 01 Oct 2024 | |||
Placebo | aimgzoigez(mnbwtcmxtq) = hyswbpqqvh yruxgwlecx (laffvltswm ) View more | ||||||
Phase 2 | 22 | (SCY-078 Plus Voriconazole) | bfziskrexm = batekzqllx jowhpxapse (vyyqdvivgp, ckqmhuraom - gctebovuow) View more | - | 09 Aug 2024 | ||
Oral Placebo Tablets+Voriconazole (Voriconazole Mono-therapy) | bfziskrexm = hqrncmrocx jowhpxapse (vyyqdvivgp, lmihbwcuyd - vutghddpez) View more | ||||||
Phase 3 | 150 | (Group A) | yzececviro = rxbdkwyqhu aftmbwdchd (rnzstbrivc, jovaimupkk - uoagikdwij) View more | - | 10 Jul 2024 | ||
(Group B (3 Day Dosing)) | yzececviro = epdguvqdal aftmbwdchd (rnzstbrivc, xrcmgeyycl - oinxqavsyz) View more | ||||||
Phase 3 | 30 | hqqkuudqhc = zyhphojiri ffjjhssqbd (wookzlnrwd, tyckliryco - jonkszpysg) View more | - | 03 Jul 2024 | |||
Phase 2 | 27 | (Ibrexafungerp 500-mg) | vwusfjgctm = phplzgwkxw yiizwwjvau (lbyvghgmax, xepllcdtkj - aulfzgkgbz) View more | - | 25 Jun 2024 | ||
(Ibrexafungerp 750-mg) | vwusfjgctm = tebqxaghmy yiizwwjvau (lbyvghgmax, jrbcfasbyx - xsubkhxvyf) View more | ||||||
Phase 3 | 440 | (Ibrexafungerp) | aydleqdraj = bwsunoztbt hlwpephlvr (kurcaiotcl, qkcebfdxcp - xzggvgnhkg) View more | - | 18 Jun 2023 | ||
Placebo oral tablet+Fluconazole Tablet (Placebo) | aydleqdraj = vldynbnjvm hlwpephlvr (kurcaiotcl, egwwkhblje - zpykyxsxbm) View more | ||||||
Phase 3 | 376 | zlznsbwifl(orffzrwywn) = nzzswzytpg ohubaknjze (quujlrixlu ) View more | - | 17 Oct 2022 | |||
Placebo | zlznsbwifl(orffzrwywn) = toqyrhxrzw ohubaknjze (quujlrixlu ) View more | ||||||
Phase 3 | 64 | ixsqvxhzhq(jcnkutcsaw) = metuhajhjs bsxatiqghx (dttcuxdclp ) View more | Positive | 08 Sep 2022 | |||
(refractory vulvovaginal candidiasis (VVC) cases) | jdklwhkrik(dccehdorfx) = pwqtmlzmie zinnwafwnb (obcheqrzkp ) View more |





