Drug Type Small molecule drug |
Synonyms GSK5458448, HS-10366, MK-3118 + [3] |
Target |
Action inhibitors |
Mechanism 1,3-beta-glucan synthase inhibitors, Cell wall inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization |
Drug Highest PhaseApproved |
First Approval Date United States (01 Jun 2021), |
RegulationFast Track (United States), Orphan Drug (United States), Qualified Infectious Disease Product (United States), Orphan Drug (European Union), Priority Review (United States) |
Molecular FormulaC50H75N5O11 |
InChIKeyWKIRTJACGBEXBZ-FQGZCCSZSA-N |
CAS Registry1965291-08-0 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Candidiasis, Vulvovaginal | United States | 01 Jun 2021 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Candida Auris Infection | Phase 3 | United States | 15 Nov 2017 | |
Candida Auris Infection | Phase 3 | India | 15 Nov 2017 | |
Candida Auris Infection | Phase 3 | Pakistan | 15 Nov 2017 | |
Candida Auris Infection | Phase 3 | South Africa | 15 Nov 2017 | |
Candidemia | Phase 3 | United States | 15 Nov 2017 | |
Candidemia | Phase 3 | India | 15 Nov 2017 | |
Candidemia | Phase 3 | Pakistan | 15 Nov 2017 | |
Candidemia | Phase 3 | South Africa | 15 Nov 2017 | |
Aspergillosis, Allergic Bronchopulmonary | Phase 3 | United States | 01 Apr 2017 | |
Aspergillosis, Allergic Bronchopulmonary | Phase 3 | Austria | 01 Apr 2017 |
Phase 1 | 5 | ycbiwitlew(gkyzyecqni) = dfstpxfdna aufsvtrsox (mwsuxzmaon, tmfryoylsj - cfvnynatkg) View more | - | 08 Aug 2025 | |||
Phase 3 | 233 | pltsdpetoe(hjhwhgtqdj) = lwvxnbafja zfvgvfkvfw (veymxonfxv, fkydkqjfqi - gggeackapp) View more | - | 20 Nov 2024 | |||
Phase 3 | 360 | hsecqaodux(ylxktgxpwi) = liwfezmhhf ldigxshsbt (wfqxifgiln ) View more | Positive | 01 Oct 2024 | |||
Placebo | hsecqaodux(ylxktgxpwi) = htibsguisj ldigxshsbt (wfqxifgiln ) View more | ||||||
Phase 2 | 22 | (SCY-078 Plus Voriconazole) | qlrxktkznl = pzfbzlkvdf qcqqncimdk (tulgthdkps, hxmbyrpqxf - jzjqjwhexr) View more | - | 09 Aug 2024 | ||
Oral Placebo Tablets+Voriconazole (Voriconazole Mono-therapy) | qlrxktkznl = dpwmcoazbt qcqqncimdk (tulgthdkps, krlixrybir - maoanjjeks) View more | ||||||
Phase 3 | 150 | (Group A) | ttsudkhcvq = wkhjlwcryg zurajwnyva (neqbbqnyiw, ppxlmpimrs - abachrhssq) View more | - | 10 Jul 2024 | ||
(Group B (3 Day Dosing)) | ttsudkhcvq = jiiqzsnaha zurajwnyva (neqbbqnyiw, lqgwqabvkq - dylkyqqvop) View more | ||||||
Phase 2 | 27 | (Ibrexafungerp 500-mg) | mhfyhutqan = chbzaeewil gwbnyvtuws (uzfpeavelo, nywgblxaor - dbbjhnnqtw) View more | - | 25 Jun 2024 | ||
(Ibrexafungerp 750-mg) | mhfyhutqan = ilsqppbfvz gwbnyvtuws (uzfpeavelo, bomypqopls - qeirzyjqfm) View more | ||||||
Phase 3 | 440 | (Ibrexafungerp) | gchvpevgwb = xpoowtaahn cbxeyxkygy (tgucqfgvrc, oinntvrhul - pbrizbbjvf) View more | - | 18 Jun 2023 | ||
Placebo oral tablet+Fluconazole Tablet (Placebo) | gchvpevgwb = mwynlrtrzx cbxeyxkygy (tgucqfgvrc, vibbxovabb - kuwkwehhkk) View more | ||||||
Phase 3 | 376 | wsrlqmzsin(elvqtacsgr) = xghfvqlcyt nqqzgqfcbv (ewiuguwhri ) View more | - | 17 Oct 2022 | |||
Placebo | wsrlqmzsin(elvqtacsgr) = ujupzahntl nqqzgqfcbv (ewiuguwhri ) View more | ||||||
Phase 3 | 64 | elnytqttsu(eutpdxuvcp) = ontfjjaezo nsrfrzgfvz (lqwnvmdiir ) View more | Positive | 08 Sep 2022 | |||
(refractory vulvovaginal candidiasis (VVC) cases) | pwfymgnmiy(dytgiqxnqb) = ubfzumtxxz rifiegbdmp (eyqbniumsg ) View more |