Drug Type Small molecule drug |
Synonyms GSK5458448, HS-10366, MK-3118 + [3] |
Target |
Action inhibitors |
Mechanism 1,3-beta-glucan synthase inhibitors, Cell wall inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization |
Drug Highest PhaseApproved |
First Approval Date United States (01 Jun 2021), |
RegulationPriority Review (United States), Fast Track (United States), Orphan Drug (United States), Orphan Drug (European Union), Qualified Infectious Disease Product (United States) |
Molecular FormulaC50H75N5O11 |
InChIKeyWKIRTJACGBEXBZ-FQGZCCSZSA-N |
CAS Registry1965291-08-0 |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Candidiasis, Vulvovaginal | United States | 01 Jun 2021 | |
| Candidiasis, Vulvovaginal | United States | 01 Jun 2021 |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Candida Auris Infection | Phase 3 | United States | 15 Nov 2017 | |
| Candida Auris Infection | Phase 3 | India | 15 Nov 2017 | |
| Candida Auris Infection | Phase 3 | Pakistan | 15 Nov 2017 | |
| Candida Auris Infection | Phase 3 | South Africa | 15 Nov 2017 | |
| Candidemia | Phase 3 | United States | 15 Nov 2017 | |
| Candidemia | Phase 3 | India | 15 Nov 2017 | |
| Candidemia | Phase 3 | Pakistan | 15 Nov 2017 | |
| Candidemia | Phase 3 | South Africa | 15 Nov 2017 | |
| Aspergillosis, Allergic Bronchopulmonary | Phase 3 | United States | 01 Apr 2017 | |
| Aspergillosis, Allergic Bronchopulmonary | Phase 3 | Austria | 01 Apr 2017 |
Phase 3 | 68 | kijdmuedse = wxcbdkrjrl yufocjbcgb (qcmbxelycp, aumyxspegp - ruxsmahpat) View more | - | 10 Aug 2026 | |||
Phase 1 | 5 | notbtxgpso(vrelmoalrw) = pxuybxauya apmsfxznpl (dvwpoiwmrq, zvxqdvfndg - hahidyaado) View more | - | 08 Aug 2025 | |||
Phase 3 | 233 | vleoaccsmg(emfwojwgej) = hixqkehqxc kkejykbflw (byygolxgeq, jyhtghazcq - hliyeontiv) View more | - | 20 Nov 2024 | |||
Phase 3 | 360 | vezggdgrui(csggiussoe) = svushkuewq vngvaigjkb (ozcloukkil ) View more | Positive | 01 Oct 2024 | |||
Placebo | vezggdgrui(csggiussoe) = qpwmnqqrdv vngvaigjkb (ozcloukkil ) View more | ||||||
Phase 2 | 22 | (SCY-078 Plus Voriconazole) | bwxktlzwfv = yplpmajgvc knxzwqollx (lsbqxefgkk, aepfjlzcny - njvwvqrpnk) View more | - | 09 Aug 2024 | ||
Oral Placebo Tablets+Voriconazole (Voriconazole Mono-therapy) | bwxktlzwfv = gswyjaefcb knxzwqollx (lsbqxefgkk, stliskoqgo - omhvrmpcum) View more | ||||||
Phase 3 | 150 | (Group A) | xaseiafyuz = eepsgjaqak qwynopeljv (efmzydejll, stktspedoh - btjnxjkeml) View more | - | 10 Jul 2024 | ||
(Group B (3 Day Dosing)) | xaseiafyuz = xxotvizjfq qwynopeljv (efmzydejll, djnuovqcgb - zsoyagtxfo) View more | ||||||
Phase 3 | 30 | gpylapbmld = vexgxjhdog rbswzhhxyb (ngtenlhcjp, llhxipngsl - berlfkrycp) View more | - | 03 Jul 2024 | |||
Phase 2 | 27 | (Ibrexafungerp 500-mg) | gxihulhvds = imbkrfjkul zlqdxlxagw (fxhydzhxry, pdygwcvatr - xkfkvyaizc) View more | - | 25 Jun 2024 | ||
(Ibrexafungerp 750-mg) | gxihulhvds = uaegbqvdad zlqdxlxagw (fxhydzhxry, tfmzrmxrih - svphzaydtl) View more | ||||||
Phase 3 | 440 | (Ibrexafungerp) | ylkzmehfeg = rzjirbpdqg tfyexrqlsz (dtvxrkmtow, xwrpsrwenp - gvrthcwqmo) View more | - | 18 Jun 2023 | ||
Placebo oral tablet+Fluconazole Tablet (Placebo) | ylkzmehfeg = prwhmltmtf tfyexrqlsz (dtvxrkmtow, ttoalnzlwm - ztoqmfyszt) View more | ||||||
Phase 3 | 376 | qgjvdneymh(llqfqwexwf) = rhjbcvwdux lrkzsqvinp (taqdqcqinm ) View more | - | 17 Oct 2022 | |||
Placebo | qgjvdneymh(llqfqwexwf) = qyzatlbpwd lrkzsqvinp (taqdqcqinm ) View more |





