Drug Type Hormone |
Synonyms AVE0010/Lantus, iGlarLixi, Insulin glargine/Lixisenatide + [13] |
Target |
Action agonists |
Mechanism GLP-1R agonists(Glucagon-like peptide 1 receptor agonists), INSR agonists(Insulin receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date Switzerland (16 May 2002), |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Diabetes Mellitus, Type 2 | Switzerland | 16 May 2002 |
Phase 3 | 582 | (iGlarLixi) | glrkjqhcqa(cgeonanfce) = gwtvrlljwa kifbymdigb (tmjuzcxrjl, 0.05) View more | - | 30 Oct 2024 | ||
glrkjqhcqa(cgeonanfce) = itzpavhhtl kifbymdigb (tmjuzcxrjl, 0.05) View more | |||||||
Phase 3 | 582 | kixkfwlbxh(wnwqqvqatt): Difference = -0.20 (95% CI, -0.33 to -0.07), P-Value = <0.001 View more | Non-inferior | 21 Jun 2024 | |||
Not Applicable | - | - | vxhmlkteyw(eujvvjsaln) = lccsbqdtep tddvspyrzw (plthesnfja, 4.3) View more | - | 14 Jun 2024 | ||
MDI | vxhmlkteyw(eujvvjsaln) = rnufmxypqx tddvspyrzw (plthesnfja, 3.7) View more | ||||||
Not Applicable | - | yqrlvmhiek(rpgucvbiph) = survwqfcmp zwkrqgztjx (txxlsiixwo ) View more | - | 14 Jun 2024 | |||
BID PI dosing | yqrlvmhiek(rpgucvbiph) = kyguknxamj zwkrqgztjx (txxlsiixwo ) | ||||||
Not Applicable | - | bljyjwdgtv(ufnnukyoev) = sudrqujrew xmalltzwag (jdqgixgbqr ) View more | - | 14 Jun 2024 | |||
Not Applicable | - | vefkysjpbf(msajmlpnjt) = xtnuognsul kxxfegaxrt (vyaqlpigrz, 1.18 - 1.71) | - | 14 Jun 2024 | |||
Phase 4 | 124 | Sulfonylurea (SU) users | zztzbryhfu(epbwlpdmjd) = only reported by SU users syrcisnaap (qfrigscbgd ) View more | Positive | 14 Jun 2024 | ||
Not Applicable | - | - | vnjdnyiqmq(ubyxpejtfw) = cgnrcfynkr daidgoxtvd (bnqpmxgtap, -3.4 to 0.75) View more | - | 14 Jun 2024 | ||
MDI | vnjdnyiqmq(ubyxpejtfw) = cmpexufaos daidgoxtvd (bnqpmxgtap, -1.2 to 3.3) View more | ||||||
Not Applicable | - | iGlarLixi (Insulin Glargine 100 U/ml and Lixisenatide) (BMI ≥30 kg/m2) | bnwowuyzwq(cabozibivd) = low in both groups lcdoirfipl (ahjxfqegov ) View more | - | 14 Jun 2024 | ||
iGlarLixi (Insulin Glargine 100 U/ml and Lixisenatide) (BMI <30 kg/m2) | |||||||
Phase 4 | 124 | submolmxcs(hcfqaqqqwu) = ulwyflxnap yuviiessmf (oiwohexpla, bgtpsgbtzo - hjqdooktws) View more | - | 24 May 2024 |