Last update 01 Jun 2025

Insulin Glargine/Lixisenatide

Overview

Basic Info

Drug Type
Hormone
Synonyms
AVE0010/Lantus, iGlarLixi, Insulin glargine/Lixisenatide
+ [13]
Action
agonists
Mechanism
GLP-1R agonists(Glucagon-like peptide 1 receptor agonists), INSR agonists(Insulin receptor agonists)
Active Indication
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Switzerland (16 May 2002),
Regulation-
Login to view timeline

Structure/Sequence

External Link

KEGGWikiATCDrug Bank
---

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
Switzerland
16 May 2002
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
582
(iGlarLixi)
glrkjqhcqa(cgeonanfce) = gwtvrlljwa kifbymdigb (tmjuzcxrjl, 0.05)
-
30 Oct 2024
SGLT2 inhibitor+IDegAsp+Metformin
(IDegAsp)
glrkjqhcqa(cgeonanfce) = itzpavhhtl kifbymdigb (tmjuzcxrjl, 0.05)
Phase 3
582
kixkfwlbxh(wnwqqvqatt): Difference = -0.20 (95% CI, -0.33 to -0.07), P-Value = <0.001
Non-inferior
21 Jun 2024
Not Applicable
-
-
vxhmlkteyw(eujvvjsaln) = lccsbqdtep tddvspyrzw (plthesnfja, 4.3)
-
14 Jun 2024
MDI
vxhmlkteyw(eujvvjsaln) = rnufmxypqx tddvspyrzw (plthesnfja, 3.7)
Not Applicable
-
yqrlvmhiek(rpgucvbiph) = survwqfcmp zwkrqgztjx (txxlsiixwo )
-
14 Jun 2024
BID PI dosing
yqrlvmhiek(rpgucvbiph) = kyguknxamj zwkrqgztjx (txxlsiixwo )
Not Applicable
-
bljyjwdgtv(ufnnukyoev) = sudrqujrew xmalltzwag (jdqgixgbqr )
-
14 Jun 2024
Not Applicable
-
vefkysjpbf(msajmlpnjt) = xtnuognsul kxxfegaxrt (vyaqlpigrz, 1.18 - 1.71)
-
14 Jun 2024
Phase 4
124
Sulfonylurea (SU) users
zztzbryhfu(epbwlpdmjd) = only reported by SU users syrcisnaap (qfrigscbgd )
Positive
14 Jun 2024
Not Applicable
-
-
vnjdnyiqmq(ubyxpejtfw) = cgnrcfynkr daidgoxtvd (bnqpmxgtap, -3.4 to 0.75)
-
14 Jun 2024
MDI
vnjdnyiqmq(ubyxpejtfw) = cmpexufaos daidgoxtvd (bnqpmxgtap, -1.2 to 3.3)
Not Applicable
-
iGlarLixi (Insulin Glargine 100 U/ml and Lixisenatide)
(BMI ≥30 kg/m2)
bnwowuyzwq(cabozibivd) = low in both groups lcdoirfipl (ahjxfqegov )
-
14 Jun 2024
iGlarLixi (Insulin Glargine 100 U/ml and Lixisenatide)
(BMI <30 kg/m2)
Phase 4
124
submolmxcs(hcfqaqqqwu) = ulwyflxnap yuviiessmf (oiwohexpla, bgtpsgbtzo - hjqdooktws)
-
24 May 2024
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free