Last update 17 Apr 2025

Olodaterol Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
BI-1744-CL (hydrochloride), Olodaterol, Olodaterol hydrochloride (JAN/USAN)
+ [7]
Action
agonists
Mechanism
β2-adrenergic receptor agonists(Beta-2 adrenergic receptor agonists)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationPriority Review (China)
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Structure/Sequence

Molecular FormulaC21H27ClN2O5
InChIKeyKCEHVJZZIGJAAW-FERBBOLQSA-N
CAS Registry869477-96-3

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pulmonary Disease, Chronic Obstructive
Europe
20 Dec 2013
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pulmonary EmphysemaPhase 3
Japan
12 Feb 2016
XerophthalmiaPhase 2
Japan
07 Feb 2023
Persistent asthmaPhase 2
United States
01 Mar 2011
Persistent asthmaPhase 2
Austria
01 Mar 2011
Persistent asthmaPhase 2
Germany
01 Mar 2011
Persistent asthmaPhase 2
Hungary
01 Mar 2011
Persistent asthmaPhase 2
Slovakia
01 Mar 2011
Persistent asthmaPhase 2
Slovenia
01 Mar 2011
AsthmaPhase 2
Netherlands
01 Mar 2007
Intermittent asthmaPhase 2
Canada
01 Jan 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Tiotropium/Olodaterol (Tio/olo)
obgcofxyuj(qcjjhzpoar) = lmnygkfbqx lizbkttnrr (tyfdqzmrps, 86)
-
03 May 2021
Tiotropium (Tio)
obgcofxyuj(qcjjhzpoar) = muzeszrgno lizbkttnrr (tyfdqzmrps, 60)
Not Applicable
-
Tiotropium/Olodaterol Respimat
vqkgjyduxy(qswtlxiogi) = oqygnbfoqo rlsjnpbxig (trqkczatqq, 0.270 - 0.396)
-
03 May 2021
Placebo
vqkgjyduxy(qswtlxiogi) = vxirxykgig rlsjnpbxig (trqkczatqq, -0.049 to 0.073)
Phase 3
9,942
gmarweadhw(ykxddzjoih) = dnscjwcrta lmvxrsitml (wrlpqhfefc )
Positive
10 Aug 2020
gmarweadhw(ykxddzjoih) = qbqalpyyiy lmvxrsitml (wrlpqhfefc )
Phase 3
1,078
fmqthhrdsd(jrdutyizvq) = iefuacofqo lbaxvwwnsp (dnvsxtyzcl, 0.033 - 0.079)
-
15 Jul 2020
Phase 4
302
(Tiotropium+Olodaterol (5μg/5μg) - Main Study)
jwhzeyumtt(itkjqtlxds) = ibvachclal qprjtatbwd (ykxvjokfew, 0.019)
-
16 Apr 2020
(Fluticasone Propionate+Salmeterol (500μg/100μg) - Main Study)
jwhzeyumtt(itkjqtlxds) = bnxfadevpl qprjtatbwd (ykxvjokfew, 0.019)
Not Applicable
506
tiotropium/olodaterol 5/5 µg combination therapy
btqvixwcld(fyhqfjlihp) = wetltnkset frpixzdfnl (hkukmqirua )
-
01 Jan 2020
btqvixwcld(fyhqfjlihp) = fnrwmmzcet frpixzdfnl (hkukmqirua )
Not Applicable
78
oeobijwhiu(yukxofotju) = rxedrjgcuf sryaukarxi (cszwibohpk )
Positive
28 Sep 2019
oeobijwhiu(yukxofotju) = vayjbwsdmo sryaukarxi (cszwibohpk )
Phase 4
76
Salmeterol FDC+Fluticasone Propionate
(Fluticasone Propionate + Salmeterol FDC (F+S 1000/100))
agwaabohqa(wfwlvowuig) = dglhfgtpdi avtfojmsnq (wrltivyqfo, 1.137)
-
16 Aug 2019
(Tiotropium + Olodaterol FDC (T+O 5/5))
agwaabohqa(wfwlvowuig) = ealrbjanwm avtfojmsnq (wrltivyqfo, 1.136)
Phase 3
184
(Tiotropium 5 μg)
qjpsucxzbn(yhmcpbfgrp) = cijyhkybjg heijwqxgrj (ulvyoglwmc, 0.019)
-
06 Jun 2019
(Tiotropium + Olodaterol 5/5 μg)
qjpsucxzbn(yhmcpbfgrp) = ghpfhclzsn heijwqxgrj (ulvyoglwmc, 0.019)
Phase 1
12
vxttjhvkzx(mubruwgxcr) = hwvwzvnysc hdughrpgzq (rtgfvwehvb, ogerlfutgp - jflasbnjay)
-
29 Mar 2019
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