Drug Type Bispecific antibody |
Synonyms BI 905711 |
Target |
Mechanism CDH17 antagonists(Cadherin-17 antagonists), DR5 agonists(Tumor necrosis factor receptor superfamily member 10B agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Gastrointestinal cancer metastatic | Phase 1 | US | 24 Nov 2021 | |
Gastrointestinal cancer metastatic | Phase 1 | CN | 24 Nov 2021 | |
Gastrointestinal cancer metastatic | Phase 1 | JP | 24 Nov 2021 | |
Gastrointestinal cancer metastatic | Phase 1 | BE | 24 Nov 2021 | |
Gastrointestinal cancer metastatic | Phase 1 | FR | 24 Nov 2021 | |
Gastrointestinal Neoplasms | Phase 1 | DE | 17 Mar 2020 | |
Gastrointestinal Neoplasms | Phase 1 | DE | 17 Mar 2020 | |
Gastrointestinal Neoplasms | Phase 1 | ES | 17 Mar 2020 | |
Gastrointestinal Neoplasms | Phase 1 | ES | 17 Mar 2020 | |
Bile Duct Neoplasms | Phase 1 | US | 11 Mar 2020 |
Phase 1 | 48 | ebevmrujwy(vbywbmxjwp) = neaaryfpkm sycsvxfrcg (gkvgsztmdh ) View more | Positive | 24 Jan 2023 | |||
(CRC) | ipkhuajjcs(znvtbyhjzz) = ncbjrpxmpg fguqhezrcj (yxduhzzyzw ) View more | ||||||
NCT04137289 (ESMO2022) Manual | Phase 1 | 45 | fttinxczlh(abmamomcci) = 2–3 days (0.6–3.6 mg/kg dose) isnzxsxtle (fbjlxyruyj ) View more | Positive | 10 Sep 2022 |