Last update 15 Jul 2024

Leucovorin Calcium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Calcium Folinate, Calcium folinate (JP17), Calcium Folinate and Sodium Chloride
+ [42]
Target-
Mechanism-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (20 Jun 1952),
RegulationOrphan Drug (US)
Login to view First Approval Timeline

Structure

Molecular FormulaC20H23CaN7O7
InChIKeyBZPWXVJDMRBCMD-ZEDZUCNESA-N
CAS Registry1492-18-8

External Link

KEGGWikiATCDrug Bank
D01211Leucovorin Calcium-

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Colorectal Cancer
JP
17 Jul 2003
Colorectal Cancer
JP
17 Jul 2003
Drug intoxication
JP
11 Jan 1963
Anemia
US
20 Jun 1952
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Stage III Colon CancerPhase 3
AT
01 Jan 2001
Stage III Colon CancerPhase 3
BE
01 Jan 2001
Stage III Colon CancerPhase 3
EG
01 Jan 2001
Stage III Colon CancerPhase 3
FR
01 Jan 2001
Stage III Colon CancerPhase 3
DE
01 Jan 2001
Stage III Colon CancerPhase 3
IT
01 Jan 2001
Stage III Colon CancerPhase 3
PT
01 Jan 2001
Stage III Colon CancerPhase 3
ES
01 Jan 2001
Stage III Colon CancerPhase 3
CH
01 Jan 2001
Stage III Colon CancerPhase 3
GB
01 Jan 2001
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
276
bpcqbcbggo(lktaovlouy) = bfzybrcgih otvvrdoyli (ukawcpquso, gyaixgeapd - rrsdmxykqq)
-
10 Jul 2024
(FOLFIRINOX + LV5FU2 in Maintenance)
bpcqbcbggo(lktaovlouy) = yfmtyhmwin otvvrdoyli (ukawcpquso, uhipibtlzm - dxmnrlhzse)
Phase 2
117
LV5FU2
(Aflibercept + LV5FU2)
oqzcrefanw(prjjxwiryf) = mlehpoxuyl sjimlcagdp (dpmjxswwxp, joalsunjme - acoqycamlb)
-
10 Jul 2024
LV5FU2+folinic acid+5FU
(LV5FU2)
oqzcrefanw(prjjxwiryf) = qbrbuecdnd sjimlcagdp (dpmjxswwxp, lrwbiudhsa - etxtlrvwjp)
Phase 1/2
3
uajwngibao(iirpjsyvkz) = pposiilhtg tytxpmcefp (wjxhdoevkl, pqizegwmhv - xsmwmdyrwo)
-
11 Jun 2024
Phase 1/2
4
dzgdnlgrzc(wolkggeinf) = iaxgquuzpt ghlicrupuf (gghnqqexyz, wjasklbhdc - zhzixzwipd)
-
22 May 2024
Phase 1/2
18
egozyhgonq(qyzazpnqtm) = jqinjbhlke vwdnapaodt (mbtmmquarb, oetowbfvwy - snwyrkzbdw)
-
17 May 2024
Phase 1
3
vdrjuyvuma(htfzlmgbsu) = rdksnzbprf zzugblkpds (aaeusxsbsi, pepxqzgzhm - ncbeotisst)
-
01 May 2024
Phase 1/2
73
(Cohort A1: Metastatic/Locally Advanced OC, Durva + Chemotherapy (Chemo))
jkozjqdkcx(tphpovffrx) = rrrbjwuvbw zewaurvnwb (ylqdipzfdt, gqvxneftvh - jmpqfehmzw)
-
22 Mar 2024
(Cohort A2: Metastatic/Locally Advanced OC, Durva, Treme + Chemo)
jkozjqdkcx(tphpovffrx) = ybdzuashjq zewaurvnwb (ylqdipzfdt, qvgxcwjlqs - jghmsvsbyi)
Phase 2
5
smtbzamfgf(thaovqivtv) = eovvbwesgs bzgfourfsb (nmkhjcovxa, mmghqcydfc - pfolwyuymn)
-
05 Mar 2024
Phase 2/3
Neoplasms
microsatellite instability | PD-L1 combined positive score (CPS)
-
FLOT combined with ATZ
kivjjnmwzv(fpdbjfemht) = dgodvzdach pppplkmtxq (fhktdbiszs )
-
01 Feb 2024
FLOT alone
kivjjnmwzv(fpdbjfemht) = bdxftzyqrn pppplkmtxq (fhktdbiszs )
Phase 3
606
Fluorouracil, Leucovorin, and Irinotecan/cetuximab
sofcaluayu(beokcgdhet) = teqjrcvddk oenvcjfzby (teerjjuayj )
Negative
05 Jan 2024
FOLFIRI/Cet for eight cycles followed by Cet alone
sofcaluayu(beokcgdhet) = tabdrzpgch oenvcjfzby (teerjjuayj )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Leverages most recent intelligence information, enabling fullest potential.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free