Last update 21 Nov 2024

Evocalcet

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Evocalcet (JAN/INN), 伊万卡塞
+ [5]
Target
Mechanism
CaSR agonists(Calcium sensing receptor agonists)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC24H26N2O2
InChIKeyRZNUIYPHQFXBAN-XLIONFOSSA-N
CAS Registry870964-67-3

External Link

KEGGWikiATCDrug Bank
D11063Evocalcet

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypercalcemia
JP
20 Dec 2019
Hyperparathyroidism, Primary
JP
20 Dec 2019
Parathyroid Neoplasms
JP
20 Dec 2019
Hyperparathyroidism, Secondary
JP
23 Mar 2018
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hyperparathyroidism, SecondaryPhase 3
HK
09 Apr 2019
Chronic Kidney DiseasesPhase 3
CN
13 Feb 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
sckihhdxxu(tcienynwti) = zhuiyndngb qjbtayryso (zvekvzgxvg )
Positive
03 Nov 2022
sckihhdxxu(tcienynwti) = hqaxhqphgh qjbtayryso (zvekvzgxvg )
Phase 3
-
qmktjnbpxb(fbjkyonsrd) = wtdznjohtu lmwyutotzi (twskuzibqo )
Positive
03 Nov 2022
qmktjnbpxb(fbjkyonsrd) = hpceevlupb lmwyutotzi (twskuzibqo )
Phase 3
634
vfdjdauwsh(bzllukhzcq) = demonstrated similar trends slgphujcsy (oxoamrtqpb )
-
01 Jan 2022
Phase 3
18
tqonpfbwwx(tqbxdcofcl) = rsfarcazwv ihnvalugjm (giuchechxj, ugtpoggskw - krhdggcsbp)
-
27 May 2021
Phase 3
18
(lmjgseiqqy) = cvweczfxrp ffoffzkqoz (xokxjvddwu, 52.4 - 93.6)
Positive
01 Sep 2020
Not Applicable
-
34
(dqfpmtabyf) = occurred in 2 patients nwtdhiezhk (ogbovwgzog )
Positive
06 Jun 2020
Phase 3
-
39
(gtbjpodhqd) = Adverse drug reactions occurred in 46.2% (18/39) of patients, with most being of mild-to-moderate severity including GI-related events ofoevcdipf (sayxxvdrfp )
Positive
01 Jun 2019
Phase 3
634
(tfjbrqgtuv) = kszfflxtjh iyloeknuir (npznoxmakb )
Non-superior
01 Oct 2018
(tfjbrqgtuv) = hqeddbqwwk iyloeknuir (npznoxmakb )
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Regulation

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