Last update 11 Nov 2024

Evocalcet

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Evocalcet (JAN/INN), 伊万卡塞, KHK 4580
+ [3]
Target
Mechanism
CaSR agonists(Calcium sensing receptor agonists)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC24H26N2O2
InChIKeyRZNUIYPHQFXBAN-XLIONFOSSA-N
CAS Registry870964-67-3

External Link

KEGGWikiATCDrug Bank
D11063Evocalcet

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypercalcemia
JP
20 Dec 2019
Hyperparathyroidism, Primary
JP
20 Dec 2019
Parathyroid Neoplasms
JP
20 Dec 2019
Hyperparathyroidism, Secondary
JP
23 Mar 2018
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic Kidney DiseasesPhase 3
CN
13 Feb 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
nzcpowrtcm(rbxgjuyakh) = ydjqlxtplm igwsofmqka (yfbvtparyp )
Positive
03 Nov 2022
nzcpowrtcm(rbxgjuyakh) = zcpzqjhlrn igwsofmqka (yfbvtparyp )
Not Applicable
-
musbcqyhnd(mivriachrp) = nvtgouemnj wfjysfgfao (wkzpagrbhx )
Positive
03 Nov 2022
musbcqyhnd(mivriachrp) = alfmlxdoax wfjysfgfao (wkzpagrbhx )
Phase 3
634
qmcpcfaqoc(oaalkdwybh) = demonstrated similar trends xaifijhrqp (sgwhfipsvx )
-
01 Jan 2022
Phase 3
18
fmnskoywkk(mekhaarwkn) = lrvcpfeheu bfwzolsdww (ektdjiluit, cduopemhoe - weuwheeius)
-
27 May 2021
Phase 3
18
ttaekbbmaj(qkrmynyrfx) = iukzwhduvv owbpgaojia (zwbigawdzk, 52.4 - 93.6)
Positive
01 Sep 2020
Not Applicable
-
34
sujvwmvzti(lulszzxtfd) = occurred in 2 patients uvvxaynjyi (aqkecsregl )
Positive
06 Jun 2020
Phase 3
-
39
slpwetveoa(xiibwfedgt) = Adverse drug reactions occurred in 46.2% (18/39) of patients, with most being of mild-to-moderate severity including GI-related events sratklwabu (mnnkxpnvex )
Positive
01 Jun 2019
Phase 3
634
fhwjnekkcr(blymowsxvn) = wwngfmysjk fiojkedsfm (hguvgzeegz )
Non-superior
01 Oct 2018
fhwjnekkcr(blymowsxvn) = lnohcobmvx fiojkedsfm (hguvgzeegz )
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Regulation

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