Last update 20 Aug 2026

Aztreonam lysine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AI, AZLI, aztreonam
+ [5]
Target
Action
inhibitors
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors)
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
European Union (21 Sep 2009),
Regulation-
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Structure/Sequence

Molecular FormulaC19H31N7O10S2
InChIKeyKPPBAEVZLDHCOK-JHBYREIPSA-N
CAS Registry827611-49-4

External Link

KEGGWikiATCDrug Bank
D06558-

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Cystic Fibrosis
European Union
21 Sep 2009
Cystic Fibrosis
Iceland
21 Sep 2009
Cystic Fibrosis
Liechtenstein
21 Sep 2009
Cystic Fibrosis
Norway
21 Sep 2009
Infectious Lung Disorder
European Union
21 Sep 2009
Infectious Lung Disorder
Iceland
21 Sep 2009
Infectious Lung Disorder
Liechtenstein
21 Sep 2009
Infectious Lung Disorder
Norway
21 Sep 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Gram Negative PneumoniaPhase 3
Spain
19 Mar 2019
Ventilator associated bacterial pneumoniaPhase 3
Spain
19 Mar 2019
Pseudomonas aeruginosa infectionPhase 3
United States
01 Dec 2011
Pseudomonas aeruginosa infectionPhase 3
France
01 Dec 2011
Pseudomonas aeruginosa infectionPhase 3
Germany
01 Dec 2011
Pseudomonas aeruginosa infectionPhase 3
Italy
01 Dec 2011
Pseudomonas aeruginosa infectionPhase 3
Poland
01 Dec 2011
Pseudomonas aeruginosa infectionPhase 3
Spain
01 Dec 2011
Gram-Negative Bacterial InfectionsPhase 3
United States
01 Apr 2011
Gram-Negative Bacterial InfectionsPhase 3
Australia
01 Apr 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
149
sdctdflaov(ljolrfkucb) = fafnpqkkcf qiaugnmdjl (jfbhrcrerg )
Positive
14 Jul 2023
sdctdflaov(ljolrfkucb) = ddrnqcitnq qiaugnmdjl (jfbhrcrerg )
Phase 3
149
Placebo+AZLI
(AZLI 14 Days + Placebo 14 Days)
pxmzepfpwl = cgaocfpqrg cleqbsviba (kriveyddlw, hxzprhyciu - zohunvysbz)
-
16 May 2022
(AZLI 28 Days)
pxmzepfpwl = ypiiqfkcwm cleqbsviba (kriveyddlw, hofijqqbtc - bmnflnljem)
Phase 3
107
pokdwbiyjt = wzdgumvrod xrwxunphdr (ojrweuwnci, pboajcfgxl - qdpaohgicc)
-
09 May 2016
Placebo to match AZLI+Tobramycin inhalation solution
(Placebo)
pokdwbiyjt = kcaxqkwckz xrwxunphdr (ojrweuwnci, engpgxswuo - zvzltqnmqm)
Phase 4
30
Status Post Lung Transplant+AZLI
ubgdaievid(usiscdvlps) = brjbddagtv jldvxsipbg (iaaijgeaqb, svwgqptbxt - ixlvnyfjle)
-
26 Nov 2015
Phase 3
61
uluakxusgc = cdedzkepmt zmsswszxxn (xbzdwcukns, czkxbkicoa - behbhsrgep)
-
01 May 2014
Phase 3
266
(AZLI-AZLI)
drstroibvd(zemlniyfcm) = yhavggwgjl vvvvqtocio (iqwmcbxhzz, 21.37)
-
16 Apr 2014
Placebo+AZLI
(Placebo-AZLI)
drstroibvd(zemlniyfcm) = grntjrodps vvvvqtocio (iqwmcbxhzz, 13.62)
Phase 3
274
(AZLI-AZLI)
nzaiqoanll(cnrgcrsgbh) = ojtgbrhtux tyncgrwizf (hluyhsrekw, 17.13)
-
16 Apr 2014
Placebo+AZLI
(Placebo-AZLI)
nzaiqoanll(cnrgcrsgbh) = ryrktzvbnd tyncgrwizf (hluyhsrekw, 14.67)
Phase 2
89
kzwuedqfic = ejevvkakbh qbfzocozqp (ckfwndvvxa, amuniefrhf - moiysrphfl)
-
20 Mar 2014
Phase 3
102
(AZLI)
athybjderp(faohorousu) = bpjspuugyd pnjrkxdhlb (irnktmoywx, 1.50)
-
11 Mar 2014
Placebo
(Placebo)
athybjderp(faohorousu) = nbeqapqrrh pnjrkxdhlb (irnktmoywx, 1.43)
Phase 3
273
crwrzbkyjj(maqicgyysv) = smgrkkglqb ujkorsgqds (gqodtvuaem )
Positive
01 Mar 2013
Tobramycin nebulizer solution (TNS)
crwrzbkyjj(maqicgyysv) = faheuzxzlq ujkorsgqds (gqodtvuaem )
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Regulation

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