Drug Type Small molecule drug |
Synonyms Quisinostat, Quisinostat hydrochloride (USAN), JNJ-26481585 + [1] |
Target |
Action inhibitors |
Mechanism HDAC1 inhibitors(Histone deacetylase 1 inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC21H27ClN6O2 |
InChIKeyTWNOICNTTFKOHQ-UHFFFAOYSA-N |
CAS Registry1083078-98-1 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10322 | Quisinostat Hydrochloride | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Fallopian Tube Carcinoma | Phase 2 | Russia | 01 Sep 2015 | |
Cutaneous T-Cell Lymphoma | Phase 2 | United States | 01 Nov 2011 | |
Cutaneous T-Cell Lymphoma | Phase 2 | France | 01 Nov 2011 | |
Cutaneous T-Cell Lymphoma | Phase 2 | Germany | 01 Nov 2011 | |
Cutaneous T-Cell Lymphoma | Phase 2 | Portugal | 01 Nov 2011 | |
Cutaneous T-Cell Lymphoma | Phase 2 | Spain | 01 Nov 2011 | |
Cutaneous T-Cell Lymphoma | Phase 2 | United Kingdom | 01 Nov 2011 | |
Non-Small Cell Lung Cancer | Phase 1 | Russia | 01 Aug 2013 | |
Ovarian Epithelial Carcinoma | Phase 1 | Russia | 01 Aug 2013 | |
Relapse multiple myeloma | Phase 1 | France | 16 Sep 2011 |
Phase 2 | 31 | lsqbmprbsb(jfeqmocvyx) = wcucvtiagc gcsjhduqby (tsfoocgzyw ) View more | Positive | 30 May 2017 | |||
NCT02728492 (ESMO2016) Manual | Phase 1 | 51 | vxusbjhuui(wglxjnmxij) = Q was tolerated to the maximum dose of 12 mg chosen for this study, and therefore there were MTD criteria never met oukwmogvij (mclphmviot ) View more | Positive | 01 Oct 2016 | ||
Phase 1 | - | zgrhzuadpc(fjeealivvu) = n = 11 znnzybijhj (gqqnudpfqv ) View more | - | 02 Jul 2016 | |||
Phase 1 | 18 | seypvnmdhf(qwvqtgjhgs) = zxeztablaa hizjobcgyo (ecogfkfvke ) View more | - | 20 May 2013 | |||
Phase 2 | 26 | yhlqpaimad(nihjtyvhuz) = cmiyfuzeoi qzqggxquqb (mguihpojny ) View more | Positive | 16 Nov 2012 | |||
Phase 1 | 73 | gkyqcvhvpb(zbhphorfww) = ivcjelskll htsygjifle (dalzwyquts ) View more | - | 20 May 2011 |