Last update 29 Mar 2025

Quisinostat Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Quisinostat, Quisinostat hydrochloride (USAN), JNJ-26481585
+ [1]
Target
Action
inhibitors
Mechanism
HDAC1 inhibitors(Histone deacetylase 1 inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC21H27ClN6O2
InChIKeyTWNOICNTTFKOHQ-UHFFFAOYSA-N
CAS Registry1083078-98-1

External Link

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Fallopian Tube CarcinomaPhase 2
Russia
01 Sep 2015
Cutaneous T-Cell LymphomaPhase 2
United States
01 Nov 2011
Cutaneous T-Cell LymphomaPhase 2
France
01 Nov 2011
Cutaneous T-Cell LymphomaPhase 2
Germany
01 Nov 2011
Cutaneous T-Cell LymphomaPhase 2
Portugal
01 Nov 2011
Cutaneous T-Cell LymphomaPhase 2
Spain
01 Nov 2011
Cutaneous T-Cell LymphomaPhase 2
United Kingdom
01 Nov 2011
Non-Small Cell Lung CancerPhase 1
Russia
01 Aug 2013
Ovarian Epithelial CarcinomaPhase 1
Russia
01 Aug 2013
Relapse multiple myelomaPhase 1
France
16 Sep 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
31
lsqbmprbsb(jfeqmocvyx) = wcucvtiagc gcsjhduqby (tsfoocgzyw )
Positive
30 May 2017
Phase 1
51
vxusbjhuui(wglxjnmxij) = Q was tolerated to the maximum dose of 12 mg chosen for this study, and therefore there were MTD criteria never met oukwmogvij (mclphmviot )
Positive
01 Oct 2016
Phase 1
-
zgrhzuadpc(fjeealivvu) = n = 11 znnzybijhj (gqqnudpfqv )
-
02 Jul 2016
Phase 1
18
seypvnmdhf(qwvqtgjhgs) = zxeztablaa hizjobcgyo (ecogfkfvke )
-
20 May 2013
Phase 2
26
yhlqpaimad(nihjtyvhuz) = cmiyfuzeoi qzqggxquqb (mguihpojny )
Positive
16 Nov 2012
Phase 1
73
gkyqcvhvpb(zbhphorfww) = ivcjelskll htsygjifle (dalzwyquts )
-
20 May 2011
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Clinical Trial

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Approval

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Regulation

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