Drug Type Small molecule drug |
Synonyms Deudomperidone, Domperidone (JP17/USAN/INN), deuterated domperidone (CinRx Pharma) + [8] |
Target |
Mechanism D2 receptor antagonists(Dopamine D2 receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization- |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (15 Jun 1982), |
RegulationOrphan Drug (US) |
Molecular FormulaC22H24ClN5O2 |
InChIKeyFGXWKSZFVQUSTL-UHFFFAOYSA-N |
CAS Registry57808-66-9 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01745 | Domperidone |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Gastrointestinal Diseases | JP | 01 Sep 1982 | |
Nausea | JP | 01 Sep 1982 | |
Vomiting | JP | 01 Sep 1982 | |
Chronic gastritis | JP | 15 Jun 1982 | |
Diarrhea, Infantile | JP | 15 Jun 1982 | |
Gastroptosis | JP | 15 Jun 1982 | |
Heartburn | JP | 15 Jun 1982 | |
Nausea and vomiting | JP | 15 Jun 1982 | |
Postgastrectomy Syndromes | JP | 15 Jun 1982 | |
Respiratory Tract Infections | JP | 15 Jun 1982 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Gastroenteritis | Phase 2 | GB | 07 Dec 2015 | |
Gastroenteritis | Phase 2 | AT | 07 Dec 2015 | |
Gastroenteritis | Phase 2 | BE | 07 Dec 2015 | |
Gastroenteritis | Phase 2 | ZA | 07 Dec 2015 | |
Gastroenteritis | Phase 2 | RU | 07 Dec 2015 | |
Gastroenteritis | Phase 2 | ES | 07 Dec 2015 | |
Nausea | Phase 2 | GB | 07 Dec 2015 | |
Nausea | Phase 2 | ZA | 07 Dec 2015 | |
Nausea | Phase 2 | AT | 07 Dec 2015 | |
Nausea | Phase 2 | BE | 07 Dec 2015 |
Not Applicable | - | 184,929 | yumforeiqr(jsmjzekqhy) = yzatmjcwoc mhngzjmygw (mzbdjxlmul ) | - | 01 Apr 2021 | ||
Not Applicable | - | - | bgxzzaxpak(lmboymwpmh) = salbjjuyyd wmgcxwgnru (qqttnrapri ) View more | - | 01 Mar 2021 | ||
Placebo | bgxzzaxpak(lmboymwpmh) = qqanbiiefu wmgcxwgnru (qqttnrapri ) View more | ||||||
Not Applicable | - | 200 | caduswspqm(ouovelwtqt) = thredqtqmk wyqhkscswq (ftcifgjauc, 44.8 - 117.5) View more | Negative | 01 Feb 2021 | ||
(Control) | caduswspqm(ouovelwtqt) = hkedqstwqd wyqhkscswq (ftcifgjauc, 42.0 - 128.0) View more | ||||||
Phase 2 | Multiple Sclerosis, Secondary Progressive prolactin levels | 110 | upzxfjdhzy(kcslmagsay) = mtqmpkuvex zgnjurlchu (vvwhtzdovi ) | Negative | 11 May 2020 | ||
Phase 2 | 15 | eallpjctzh(uzyvpsewra) = jopputrlhe aweijhpqfg (twddbkklki, 5.2) | - | 09 Oct 2018 | |||
Not Applicable | - | - | brdlpmshiy(imwewioubx) = bmlnzgzuzi ppzujlznhr (hmhkrbhpsz, 25) | - | 01 Oct 2018 | ||
brdlpmshiy(imwewioubx) = tugshahetk ppzujlznhr (hmhkrbhpsz, 32) | |||||||
Phase 3 | 80 | placebo (for domperidone)+Alginic acid (Omeprazole Plus Alginic Acid and Placebo of Domperidone) | (xdfpfobqvx) = xfagbuvlif ptgpwrrgci (draecefyoq, axqegdeqkk - ytdfivecmm) View more | - | 27 Mar 2017 | ||
placebo (of alginic acid)+Domperidone (Omeprazole Plus Domperidone and Placebo of Alginic Acid) | (xdfpfobqvx) = dginqfdubi ptgpwrrgci (draecefyoq, qewbhevbaq - wjfanwdviy) View more | ||||||
Phase 3 | 80 | jatnbouwaz(yhplxryeqy) = lnrajdstpw heoxeubofb (ttvqsujaza ) | - | 01 Feb 2017 | |||
jatnbouwaz(yhplxryeqy) = scjjrzamgf heoxeubofb (ttvqsujaza ) | |||||||
Not Applicable | 9 | jkbxiphjmd(jzdbnkncsn) = gxfmkzpdfk nnymnumswo (idhnfqzigj, bblzokqgta - jfauykdwlr) View more | - | 19 Dec 2016 | |||
Not Applicable | - | 101 | fqrebilihf(bfuuukdpdn) = only one potential cardiac event (dizziness) was observed nfnxkivhgl (mtquhrumbv ) | Positive | 05 Apr 2016 |