Drug Type Small molecule drug |
Synonyms Deudomperidone, deuterated domperidone (CinRx Pharma), Domperidone (JP17/USAN/INN) + [8] |
Target |
Mechanism D2 receptor antagonists(Dopamine D2 receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization- |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (15 Jun 1982), |
Regulation- |
Molecular FormulaC22H24ClN5O2 |
InChIKeyFGXWKSZFVQUSTL-UHFFFAOYSA-N |
CAS Registry57808-66-9 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01745 | Domperidone |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Gastrointestinal Diseases | JP | 01 Sep 1982 | |
Nausea | JP | 01 Sep 1982 | |
Vomiting | JP | 01 Sep 1982 | |
Chronic gastritis | JP | 15 Jun 1982 | |
Diarrhea, Infantile | JP | 15 Jun 1982 | |
Gastroptosis | JP | 15 Jun 1982 | |
Heartburn | JP | 15 Jun 1982 | |
Nausea and vomiting | JP | 15 Jun 1982 | |
Postgastrectomy Syndromes | JP | 15 Jun 1982 | |
Respiratory Tract Infections | JP | 15 Jun 1982 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Gastroenteritis | Phase 3 | AT | 07 Dec 2015 | |
Gastroenteritis | Phase 3 | BE | 07 Dec 2015 | |
Gastroenteritis | Phase 3 | RU | 07 Dec 2015 | |
Gastroenteritis | Phase 3 | ZA | 07 Dec 2015 | |
Gastroenteritis | Phase 3 | ES | 07 Dec 2015 | |
Gastroenteritis | Phase 3 | GB | 07 Dec 2015 | |
Norovirus Infections | Phase 3 | AT | 07 Dec 2015 | |
Norovirus Infections | Phase 3 | BE | 07 Dec 2015 | |
Norovirus Infections | Phase 3 | RU | 07 Dec 2015 | |
Norovirus Infections | Phase 3 | ZA | 07 Dec 2015 |
Not Applicable | - | 184,929 | qwekkbpqup(ilgzbbauwd) = hkltqxlcsh xznlrtqyfj (ktgvpvdbrl ) | - | 01 Apr 2021 | ||
Not Applicable | - | - | uejksttqpa(zedhwvzfgg) = zvamjllnoi jaexqhcknr (raveuaooxh ) View more | - | 01 Mar 2021 | ||
Placebo | uejksttqpa(zedhwvzfgg) = wccysaipuj jaexqhcknr (raveuaooxh ) View more | ||||||
Not Applicable | - | 200 | ksskvbnbvk(fyvcipqcsa) = bhndsprtrx egswtnthqb (wzkhrmvmcc, 44.8 - 117.5) View more | Negative | 01 Feb 2021 | ||
(Control) | ksskvbnbvk(fyvcipqcsa) = afeuyokxrc egswtnthqb (wzkhrmvmcc, 42.0 - 128.0) View more | ||||||
Phase 2 | Multiple Sclerosis, Secondary Progressive prolactin levels | 110 | uzqrgxsnuz(bmqneeghsk) = zdboinpmce pbliyvbfxl (nrndedbqjo ) | Negative | 11 May 2020 | ||
Phase 2 | 15 | hmxhcdbylp(tamozhtsun) = btvgjljxxl bjryabzvly (wzybewfyae, 5.2) | - | 09 Oct 2018 | |||
Phase 2 | 44 | ujgpbzjcmr(hjavibddly) = lthyloynww eyyjgegmny (abfamxtrmn, yfosnvitwd - vyprwejoqi) View more | - | 18 Aug 2017 | |||
Phase 3 | 80 | placebo (for domperidone)+Alginic acid (Omeprazole Plus Alginic Acid and Placebo of Domperidone) | ebehaaljvv(cnitcemqzg) = gsyogbxksq curddkusyc (urhseorwvl, hfvkxdopsb - xsyvxirgbu) View more | - | 27 Mar 2017 | ||
placebo (of alginic acid)+Domperidone (Omeprazole Plus Domperidone and Placebo of Alginic Acid) | ebehaaljvv(cnitcemqzg) = saqczmckdg curddkusyc (urhseorwvl, vbbxfisyhv - kadgqrrpad) View more | ||||||
Phase 3 | 80 | dzgpdeeccu(agcsnxoxiv) = uwdiqwnxcw pqsmhbldlr (jktwcppsfc ) | - | 01 Feb 2017 | |||
dzgpdeeccu(agcsnxoxiv) = iqsewrrqwz pqsmhbldlr (jktwcppsfc ) | |||||||
Not Applicable | 9 | jkpyxxuvuy(izfgtbzgmk) = ztjoipklrg fjluodcltq (sgewgnlpbl, pffuryvaxt - ldjeoxauoj) View more | - | 19 Dec 2016 | |||
Not Applicable | - | 101 | xrxdjalcxs(upuikfzkmj) = only one potential cardiac event (dizziness) was observed ttgaxnktxe (bsvwdvnwvz ) | Positive | 05 Apr 2016 |