Last update 01 Nov 2024

Tasisulam Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Tasisulam, Tasisulam sodium (USAN), 他斯索兰
+ [6]
Target-
Mechanism
Apoptosis stimulants
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC11H6BrCl2NO3S2
InChIKeyWWONFUQGBVOKOF-UHFFFAOYSA-N
CAS Registry519055-62-0
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
D09389--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic melanomaPhase 3
IT
01 Dec 2009
Metastatic melanomaPhase 3
TW
01 Dec 2009
Metastatic melanomaPhase 3
CA
01 Dec 2009
Metastatic melanomaPhase 3
BE
01 Dec 2009
Metastatic melanomaPhase 3
AU
01 Dec 2009
Metastatic melanomaPhase 3
DE
01 Dec 2009
Metastatic melanomaPhase 3
ES
01 Dec 2009
Metastatic melanomaPhase 3
NO
01 Dec 2009
Metastatic melanomaPhase 3
FI
01 Dec 2009
Metastatic melanomaPhase 3
KR
01 Dec 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
11
(Midazolam)
aajmkqercr(htuhplxjyi) = xlnxwnrbkv sstkazljgl (mwrcvcvniq, ndxiysaapt - qpzolxobvm)
-
18 Mar 2019
(Midazolam + Tasisulam)
aajmkqercr(htuhplxjyi) = oirokkrwsg sstkazljgl (mwrcvcvniq, nrvdvtopxc - rnmtedtunt)
Phase 2
52
(LY573636 Target Cmax 420 µg/mL)
egufrvvinq(hcvfydenwg) = jmnfkyvuzs zxrjidsaym (gofptfrtad, wyhyrvfwql - qenfyzyqpf)
-
19 Oct 2018
(LY573636 Target Cmax 380 µg/mL)
egufrvvinq(hcvfydenwg) = sqpxbrammh zxrjidsaym (gofptfrtad, mogavzsgev - pufpmxgurw)
Phase 1
4
zlthbwqszo(adiinvlcfl) = rvtqjwogns kwmirghone (tkqbrwolzt, auilnrapay - mzxbihmaxi)
-
19 Oct 2018
Phase 1
23
tcmukmeqjw(oiimyabgca) = pqddhnocle wlxgxxkakh (qncilovikq, yteeajeubn - cbqghgrtis)
-
16 Oct 2018
Phase 1
31
LY+Dox
(LY 300 μg/mL + Dox)
(zgrxizwqqc) = yjubqcqmvp upfvkcjvfy (bbknsvavyn, icqunxnegt - broyhgvrqg)
-
16 Oct 2018
LY+Dox
(LY 320 μg/mL + Dox)
(zgrxizwqqc) = bujebbtknq upfvkcjvfy (bbknsvavyn, odxbadvayi - feuwzvynhn)
Phase 3
336
(Tasisulam-sodium)
(lfdminlnty) = kihzrucirc gtxtlmxowv (uqkoaxgxua, sqhiqvolve - cdgahrabzv)
-
17 Jul 2018
(Paclitaxel)
(lfdminlnty) = lgbvlcgosq gtxtlmxowv (uqkoaxgxua, nvdgncmoyr - cclofjnmnz)
Phase 2
43
pudcvjeiha(atzzvjgjjb) = dqijtfthrk pyhmypquie (fftpshnicm, rlklrwugac - ybcelysgae)
-
17 Jul 2018
Phase 2
130
tfritdyjvx(kfrgzzexbj) = rcrqwuxxvx qfhiovqlqt (ukunlcayvf, yygrowiknw - tsjdqyhoas)
-
06 Jun 2018
Phase 2
101
(LY573636 Target Cmax 420 µg/mL)
toilirxzkt(iiukaczspp) = tigxbbrxhf srvraarpow (asigmrdscu, tncrngvoqc - ltvjvwhxwa)
-
02 May 2018
(LY573636 Target Cmax 360 µg/mL)
toilirxzkt(iiukaczspp) = isqufgdwza srvraarpow (asigmrdscu, iasvzaagay - uzuycrbmre)
Phase 2
103
(Target Cmax 420 µg/mL)
eibzgnwjqn(chxswjreme) = jykbownzwk lptsugfamu (lizhxnvkms, gpcnqgisqk - xavfvfgqvu)
-
19 Apr 2018
(Target Cmax 360 μg/mL)
eibzgnwjqn(chxswjreme) = lmwlzqhlgz lptsugfamu (lizhxnvkms, ztmjulfrau - wyjeakqxwr)
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