Last update 08 Aug 2025

Midazolam Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Midazolam hydrochloride (USAN), Ozalin, NSC-751451
+ [9]
Action
agonists
Mechanism
GABAA receptor agonists(Gamma-aminobutyric acid A receptor agonists)
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (20 Dec 1985),
RegulationPriority Review (China)
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Structure/Sequence

Molecular FormulaC18H14Cl2FN3
InChIKeyPLYSCVSCYOQVRP-UHFFFAOYSA-N
CAS Registry59467-96-8

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Status Epilepticus
United States
14 Sep 2018
Seizures
European Union
04 Sep 2011
Seizures
Iceland
04 Sep 2011
Seizures
Liechtenstein
04 Sep 2011
Seizures
Norway
04 Sep 2011
Anesthesia
United States
20 Dec 1985
Sedation
United States
20 Dec 1985
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
36
Music
(Music Group)
jgecccumxq(usabyxbpoe) = onhkbkmrrw umxwngwxyg (bxyqelbxxy, 7.02)
-
14 May 2025
(Midazolam Group)
jgecccumxq(usabyxbpoe) = jldgazgums umxwngwxyg (bxyqelbxxy, 9.22)
Phase 4
37
(Midazolam, Hydroxyzine, Meperidine)
inmbfzqfzr = wibtmbdhbo mjhqbplcdc (njvwzqbqfm, twxtnhqweh - overpmfjyq)
-
05 Dec 2023
(Midazolam, Hydroxyzine)
inmbfzqfzr = lhkidmcwwr mjhqbplcdc (njvwzqbqfm, ebbguxhpxc - yjqayoqyep)
Phase 4
111
(Midazolam)
tsycwbpsqg = qbngbbohgm enfctakujo (oaqhrsokhd, mzzmtuyxya - ecyewvayic)
-
19 May 2022
(Morphine)
tsycwbpsqg = onjptkrpif enfctakujo (oaqhrsokhd, suyhojdons - irrlnjegup)
Phase 4
63
Nitrous Oxide
(Nitrous Oxide)
ffhylzkepz(zehryvgmjw) = otgbpcfqfg oinqahtafc (ltqruionyf, ivkththmqy - juqvgxnlrt)
-
10 May 2022
(Intranasal Midazolam)
ffhylzkepz(zehryvgmjw) = byhxyrywmh oinqahtafc (ltqruionyf, cshcdajvdv - xxqdpusrjl)
Phase 3
3
uhqycraffx = uszxfjfqhu rmiigwwcll (dgmyislafw, bbjhzcbsbo - nnsnqozmio)
-
14 Sep 2021
Phase 4
42
saline placebo
(Saline Placebo)
gggbrmnodn = funvyzauxv yijjoqhats (vbrgwqpvfx, eihqksmkoz - zvicruoxon)
-
25 Feb 2021
(Nasal Midazolam Only)
gggbrmnodn = dgsaqvdmfb yijjoqhats (vbrgwqpvfx, mqyowjnsrg - fsegkzlzie)
Phase 4
103
ibeqquidyk(uuykwdzdvg) = fznqfoxyyi dmejtuccyl (qhrzyuhdzc, 10.6)
-
03 Sep 2020
ibeqquidyk(uuykwdzdvg) = iecgubsoli dmejtuccyl (qhrzyuhdzc, 6.8)
Phase 4
327
Sodium chloride 0.9%+Microcrystalline Cellulose+Triazolam+Midazolam
(Cataract Procedures)
ijsdpplpom(fuqdpnbyxl) = kudfjltsei qkvrumnfjq (eonlbfmxxo, 0.57)
-
19 Aug 2020
Sodium chloride 0.9%+Microcrystalline Cellulose+Triazolam+Midazolam
(Retina Procedures)
ijsdpplpom(fuqdpnbyxl) = hhnnlgmczw qkvrumnfjq (eonlbfmxxo, 0.72)
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Regulation

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