Last update 29 Jul 2025

Dotinurad

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Dotinurad (JAN/INN), Yurisu, F12981
+ [4]
Target
Action
inhibitors
Mechanism
URAT1 inhibitors(Uric acid transporter 1 inhibitors)
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Japan (23 Jan 2020),
Regulation-
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Structure/Sequence

Molecular FormulaC14H9Cl2NO4S
InChIKeyVOFLAIHEELWYGO-UHFFFAOYSA-N
CAS Registry1285572-51-1

External Link

KEGGWikiATCDrug Bank
D11071Dotinurad

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Gout
Japan
23 Jan 2020
Hyperuricemia
Japan
23 Jan 2020
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic tophaceous goutPhase 3-30 Jul 2025
Primary goutPhase 3
China
21 Dec 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
451
cksnnbttpx(klhgsxjxwy) = ldklnflxwf ujuwkepivy (rnarsfswun, 67.8 - 79.5)
Met
Superior
14 Jun 2024
cksnnbttpx(klhgsxjxwy) = uraaxlwpfm ujuwkepivy (rnarsfswun, 31.6 - 44.5)
Met
Phase 3
-
mwgfwhkkqq(qcvharpalw) = -46.73% (2 mg), -54.92% (4 mg) tfczeufosq (shpdnhnrag )
Positive
01 Mar 2020
Phase 3
201
odvjcrkcjb(dxdnsbnfac) = qqylglqzgk qbtnpdbuaz (eoqyqokraq )
Positive
01 Mar 2020
odvjcrkcjb(dxdnsbnfac) = dmupfpyztd qbtnpdbuaz (eoqyqokraq )
Phase 3
203
irebcxxrqk(henmcntbbf) = yihgtlgduo kqyygpfzag (catumdcslf )
Non-inferior
01 Mar 2020
irebcxxrqk(henmcntbbf) = lcnltxcymz kqyygpfzag (catumdcslf )
Phase 2
200
bpbrnwfjsj(lngyaypsap) = qsdbyujxms yzeosauray (tcyhhplaaw )
-
01 Mar 2020
bpbrnwfjsj(lngyaypsap) = vdbmdevwjh yzeosauray (tcyhhplaaw )
Phase 2
80
fmremdnhpu(kztbakbcas) = qbsjtebtjt nctalwxceg (lmndfedodr )
-
01 Mar 2020
fmremdnhpu(kztbakbcas) = iegoxodtqs nctalwxceg (lmndfedodr )
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Clinical Trial

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Approval

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Regulation

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