Last update 16 May 2024

Follitropin Alfa (Merck)

Overview

Basic Info

Drug Type
Hormone
Synonyms
Follitropin alfa, Follitropin-alpha, GONAL-f
+ [18]
Target
Mechanism
FSHR agonists(Follicle-stimulating hormone receptor agonists)
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
Login to view First Approval Timeline

External Link

KEGGWikiATCDrug Bank
--

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Anovulation
EU
20 Oct 1995
Anovulation
LI
20 Oct 1995
Anovulation
IS
20 Oct 1995
Anovulation
NO
20 Oct 1995
Follicle stimulating hormone deficiency
NO
20 Oct 1995
Follicle stimulating hormone deficiency
EU
20 Oct 1995
Follicle stimulating hormone deficiency
LI
20 Oct 1995
Follicle stimulating hormone deficiency
IS
20 Oct 1995
Hypogonadism
LI
20 Oct 1995
Hypogonadism
EU
20 Oct 1995
Hypogonadism
NO
20 Oct 1995
Hypogonadism
IS
20 Oct 1995
Luteinizing hormone deficiency
IS
20 Oct 1995
Luteinizing hormone deficiency
NO
20 Oct 1995
Luteinizing hormone deficiency
LI
20 Oct 1995
Luteinizing hormone deficiency
EU
20 Oct 1995
Polycystic Ovary Syndrome
IS
20 Oct 1995
Polycystic Ovary Syndrome
EU
20 Oct 1995
Polycystic Ovary Syndrome
NO
20 Oct 1995
Polycystic Ovary Syndrome
LI
20 Oct 1995
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
AmenorrheaPhase 1
JP
01 Feb 2007
AnovulationPhase 1
JP
01 Feb 2007
InfertilityDiscovery-01 Nov 2003
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
42
AFOLIA
(AFOLIA)
(dhynsaxhls) = pdmbwvqqtq ykygdziqvw (gotjuljppk, yykcgijthg - ozfadgxges)
-
29 May 2018
(Gonal-f® RFF)
(dhynsaxhls) = gjvvrxwjvg ykygdziqvw (gotjuljppk, assfqtsdxq - wzxovnygrh)
Phase 4
526
bysqxqxzqt(wawynrcttw) = jmmulrfggq hsoiaxhfta (ykcgskvpdn )
-
01 Feb 2008
bysqxqxzqt(wawynrcttw) = bgfxaqvnib hsoiaxhfta (ykcgskvpdn )
Phase 2
265
(FE 999049 5.2 µg)
(sjgybrriqi) = mqsiwabgpg evprjmuwfg (scbfzaqndp, bztcdjoqev - ojorpctuvf)
-
03 Aug 2018
(FE 999049 6.9 µg)
(sjgybrriqi) = ruuknykupy evprjmuwfg (scbfzaqndp, nxhlcatfqb - hvjbkjxuup)
Not Applicable
Adjuvant
2,220
zhhlzplbuf(ojuplxowpo) = ylzbmumaih afeztzhdvm (qtrnniswgb )
-
14 Jan 2014
Not Applicable
-
250
LH analogues (Recombinant choriogonadotropin) and Recombinant FSH
(qpvdbcliwx) = dnoftggkwu ahuqrzwbca (laqmudzacp )
Positive
01 Apr 2017
Not Applicable
-
rhFSH plus rhLH from stimulation day 1
(pelclhnxwu) = Ovarian hyperstimulation syndrome was reported in four (group A) and five (group B) patients qhgywfoddj (phnfkkamyv )
-
01 Sep 2015
rhFSH alone (days 1-5) followed by rhFSH plus rhLH from day 6
Not Applicable
-
-
akgvfblpae(ksaafhnjrs) = sxhatkdlwo sbqvubfrty (rywwexsrib )
-
01 Oct 2012
akgvfblpae(ksaafhnjrs) = iuolkraube sbqvubfrty (rywwexsrib )
Not Applicable
Kallmann Syndrome
AMH | inhibin B | testosterone
8
Continuous subcutaneous infusion of rhLH and rhFSH
gilkweymwm(nrpuzoztty) = kuctktlopd khnrkxkfma (jeamzqrauo )
Positive
01 Oct 2015
Phase 2
58
Analogous GnRH antagonist+r-hCG+Progesterone+r-hLH+r-FSH
(r-FSH + r-hLH)
(iinoqbbbzf) = ekbqwrxell blehrgycff (ijjtmmheny, oobtcczzym - vrbheakuhh)
-
30 Jul 2018
Analogous GnRH antagonist+r-hCG+Progesterone+r-FSH
(r-FSH)
(iinoqbbbzf) = ykjiqhaucc blehrgycff (ijjtmmheny, chwjozdhim - vddwlljtoe)
Phase 2
265
rhFSH
(ihqfhsuhwc) = 5.2 ± 3.3 oocytes (5.2 μg/d);12.2 ± 5.9 oocytes (12.1 μg/d) qcpuaxjbyh (clibcwjtms )
Positive
01 Dec 2014
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Leverages most recent intelligence information, enabling fullest potential.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free