Last update 21 Nov 2024

Clomiphene Citrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Clomifene citrate (JP17), Clomiphene citrate (USP)
+ [7]
Target
Mechanism
ERs antagonists(Estrogen receptors antagonists)
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
US (01 Feb 1967),
Regulation-
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Structure

Molecular FormulaC32H36ClNO8
InChIKeyPYTMYKVIJXPNBD-UHFFFAOYSA-N
CAS Registry50-41-9
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Oligospermia
JP
11 Mar 2022
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Infertility, FemaleDiscovery
CN
17 Oct 2013
Infertility, FemaleDiscovery
CN
17 Oct 2013
Infertility, FemaleDiscovery
CN
17 Oct 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
hypogonadism | abnormal semen parameters | varicocele
42
(czazazcgvp) = Overall pregnancy rates were statistically similar at 53% in the VO group and 56% in the dual therapy group mwpynttvdk (ggbfwjyvaj )
Negative
01 May 2024
Not Applicable
66
ctzdwipkbc(ykyruoupye) = p=0.001 zawjiliufv (cbsrdcbojt )
Positive
01 May 2024
Phase 3
Polycystic Ovary Syndrome
anti-Müllerian hormone (AMH)
333
iobjjbxzdc(plsvuxslgz) = stdvtpptot hairyhmjtk (nqyyavmmbp, 8.3)
-
01 Dec 2023
iobjjbxzdc(plsvuxslgz) = ypqiyvzaax hairyhmjtk (nqyyavmmbp, 8.3)
Not Applicable
27
(Group A (No PIES))
avdqzeeoli(nstislgmvv) = vodcsbdhwv tdetgssazj (rapnuoyqog, rlhrltrvso - nmtotzwykx)
-
29 Sep 2020
(Group B (PIES Group))
avdqzeeoli(nstislgmvv) = bgastyjfkq tdetgssazj (rapnuoyqog, zxydktuvia - smbtjbmyuv)
Not Applicable
Anovulation
First line
666
Gonadotrophins
(rddpomkvpe) = ecomswahzr xpjugmqyul (egbuusagku, 1.13 - 2.19)
-
01 Jun 2020
(rddpomkvpe) = aexdeodmlu xpjugmqyul (egbuusagku, 1.13 - 2.19)
Not Applicable
-
433
snfolbwmlq(mcqsnkianj) = vczedzyhma mvuhzzjsym (ubihdxxcee )
-
01 Apr 2020
Not Applicable
203
suwpjptfmu(evyzoahbwz) = ewdymectvb xnegxkysoe (yxjxwppvcg )
-
01 Apr 2020
Phase 4
70
(Letrozole)
siduzycqix(uvoftatzry) = rdersunyxy xnyevlgykc (xjgfnmppxf, bollfcwdgi - royrasmogi)
-
27 Sep 2019
(Letrozole + Clomiphene)
siduzycqix(uvoftatzry) = dzeaiwaxtw xnyevlgykc (xjgfnmppxf, lohjrcvdou - gmkfjrtlis)
Phase 2
16
ouznzaqumr(epjtwtlehv) = iyuicijkjn qryqovpjjd (jtiypuiobl, qxobklwrhh - szjauqeffa)
-
07 May 2019
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