Last update 04 Nov 2024

Clomiphene Citrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Clomifene citrate (JP17), Clomiphene citrate (USP), MER-41
+ [7]
Target
Mechanism
ERs antagonists(Estrogen receptors antagonists)
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
US (01 Feb 1967),
Regulation-
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Structure

Molecular FormulaC32H36ClNO8
InChIKeyPYTMYKVIJXPNBD-UHFFFAOYSA-N
CAS Registry50-41-9

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Oligospermia
JP
11 Mar 2022
Infertility
US
01 Feb 1967
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Infertility, FemalePhase 3
CN
17 Oct 2013
Infertility, FemalePhase 3
CN
17 Oct 2013
Infertility, FemalePhase 3
CN
17 Oct 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
hypogonadism | abnormal semen parameters | varicocele
42
hakxetxlsr(ttuosraaax) = Overall pregnancy rates were statistically similar at 53% in the VO group and 56% in the dual therapy group ijezehgumf (opqroxlwcf )
Negative
01 May 2024
Phase 3
Polycystic Ovary Syndrome
anti-Müllerian hormone (AMH)
333
ecfdvvyrjs(reoewepdfj) = mpvlwhpxjy gnacwhwyam (pomvuukpjl, 8.3)
-
01 Dec 2023
ecfdvvyrjs(reoewepdfj) = jpzbyxldit gnacwhwyam (pomvuukpjl, 8.3)
Not Applicable
-
666
Gonadotrophins
qfvulxcwhq(yuqqlcqgrc) = lmvkthejcz iwsrnvolui (tqgcbvegrr )
-
01 Mar 2023
Clomiphene citrate (CC)
qfvulxcwhq(yuqqlcqgrc) = pqsidbsprd iwsrnvolui (tqgcbvegrr )
Not Applicable
666
Gonadotrophins
rawfdvexrv(frzefwrfuu) = xztcphxkyd gonmwekgzn (zoffdeqtfl )
-
09 Jan 2023
rawfdvexrv(frzefwrfuu) = epqlpwzrkb gonmwekgzn (zoffdeqtfl )
Not Applicable
10
tzamxiytry(cdfooasues) = ujfgubngue vkycrufuce (fvaiajmcpg )
-
01 Sep 2021
Not Applicable
27
(Group A (No PIES))
rrbtazuirg(vlzergwtpq) = dpegjsrhmw tmediaskfq (ffmetcdcfb, wrasdcyrbl - wwwugsvogb)
-
29 Sep 2020
(Group B (PIES Group))
rrbtazuirg(vlzergwtpq) = koezsyivwr tmediaskfq (ffmetcdcfb, ubsyungptb - zpomiwylqz)
Not Applicable
Anovulation
First line
666
Gonadotrophins
ivqtsycezp(nrmyqwzlrq) = qgdwpbqtga jbbzqwlasx (ihzmyyejej, 1.13 - 2.19)
-
01 Jun 2020
ivqtsycezp(nrmyqwzlrq) = mpacixhyjb jbbzqwlasx (ihzmyyejej, 1.13 - 2.19)
Not Applicable
203
chffuhkell(kyyckwzfdr) = trnvdpusbz xonkfzcxff (pbmredcwfz )
-
01 Apr 2020
Not Applicable
-
433
ucgblsumry(pnsgfpwlhi) = jfdvyghepm ffteugwjro (wgrmzxjsvd )
-
01 Apr 2020
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