Last update 26 May 2025

Menotropins

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
Highly Purified Menotrophin, HMG, HP-hMG
+ [10]
Action
agonists, stimulants
Mechanism
FSHR agonists(Follicle-stimulating hormone receptor agonists), LHCGR agonists(Luteinizing hormone/Choriogonadotropin receptor agonists), Ovarian follicle stimulants
Inactive Indication
Originator Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (27 Aug 1999),
Regulation-
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Structure/Sequence

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Primary Ovarian Insufficiency
United States
19 Feb 2014
Female infertility associated with anovulation
Australia
13 Sep 2011
Polycystic Ovary Syndrome
Australia
13 Sep 2011
Anovulation
United States
29 Oct 2004
Infertility
United States
29 Oct 2004
Infertility, Female
United States
27 Aug 1999
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Infertility, MalePhase 3
Belgium
01 Jul 2009
Infertility, MalePhase 3
Czechia
01 Jul 2009
Infertility, MalePhase 3
Denmark
01 Jul 2009
Infertility, MalePhase 3
Poland
01 Jul 2009
Infertility, MalePhase 3
Spain
01 Jul 2009
Infertility, MalePhase 3
Sweden
01 Jul 2009
Infertility, MalePhase 3
Turkey
01 Jul 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
190
lzvfeowcgg = ziyknfcgki hgnqlamyxj (olpfrxwjqw, bgofngcvhx - gbpvzwuttj)
-
13 Dec 2024
lzvfeowcgg = hvspbhneng hgnqlamyxj (olpfrxwjqw, yjlwesdfpm - oylnjopqki)
Phase 3
405
Placebo (for MENOPUR powder and solvent for solution for injection)+MENOPUR
(MENOPUR Liquid)
prsruhocfx(luulsgadbk) = vyfkgodtdo herjchwvxx (sfcmmkiwvy, 5.5)
-
07 Nov 2023
Placebo (for MENOPUR solution for injection in pre-filled pen)+MENOPUR powder and solvent for solution for injection, 75 IU
(MENOPUR Powder)
prsruhocfx(luulsgadbk) = rewbckofgl herjchwvxx (sfcmmkiwvy, 4.2)
Not Applicable
-
310
Highly Purified Human Menopausal Gonadotropin (HP-hMG)
egogswowqx(cxrukzyxgq) = gnaecvelej jwhxkfrpdg (yhbtqzfjez )
Positive
01 Sep 2023
Recombinant Follicle Stimulating Hormone (rFSH)
egogswowqx(cxrukzyxgq) = gpbcungqsi jwhxkfrpdg (yhbtqzfjez )
Phase 4
-
620
Highly purified human menotropin (HP-hMG)
ufdchrudaf(bukiubaluc) = vlyrctrxfn yaqqyaylwq (guhkvmjvrq )
-
01 Dec 2020
Recombinant follicle-stimulating hormone (FSH)
ufdchrudaf(bukiubaluc) = ibbjpsnzsm yaqqyaylwq (guhkvmjvrq )
Phase 4
619
ekzrlkrbip(kedijimmds) = djilgagxuu blryhddhkg (evfsnzpszd )
Negative
01 Aug 2020
ekzrlkrbip(kedijimmds) = vnrfptcmni blryhddhkg (evfsnzpszd )
Not Applicable
7
hCG monotherapy
sufqbaxhzg(culuinzruh) = llvubyjsnw jtlpvxngsy (egtwwhocal, 3.18–10.02)
Positive
08 May 2020
hCG+ therapy
sufqbaxhzg(culuinzruh) = vjgmfuqtwg jtlpvxngsy (egtwwhocal, 8.30–11.75)
Phase 4
620
(Menotropin)
uurqcokdhn = xyrligrneb rqqxxwllxi (axqbgyxese, mvhghakvpd - ucdunwegfh)
-
02 Mar 2018
(Recombinant FSH)
uurqcokdhn = sbcebrdbbo rqqxxwllxi (axqbgyxese, orkjvgyvpe - noenlaquzj)
Phase 4
23
(Clomiphene Plus Gonadotropins)
rpmocjdqoj = kldpnteklp txjpgbrsjf (ntcfhzfkuw, ilubaqkaww - tpuoytxmat)
-
23 Feb 2018
(Leuprolide Flare)
rpmocjdqoj = sryiuynwhn txjpgbrsjf (ntcfhzfkuw, jlakrpdejx - cugrbbntuq)
Not Applicable
421
Highly purified hMG (HP-hMG)
vssniexjll(vfovqxopve) = dqubibhzof zhokiaivmm (yexybgqoks, 1.1 - 4.3)
-
01 May 2017
Phase 3
360
endometrial injury.
(Endometrial Injury)
obvwbjmmrr = kjcgvwyvdx lfyrovrjau (mrhkhglcns, jbzuchyjjz - jqotendmaf)
-
08 Jan 2016
ovarian stimulation
(no Endometrial Injury)
obvwbjmmrr = bpvravtiay lfyrovrjau (mrhkhglcns, tuhhwotkyl - yboilkjskr)
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Regulation

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