Last update 19 Jul 2024

Levocarnitine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(-)-Carnitine, (-)-L-Carnitine, (R)-Carnitine
+ [33]
Target
Mechanism
CRAT stimulants(carnitine O-acetyltransferase stimulants)
Inactive Indication
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC7H15NO3
InChIKeyPHIQHXFUZVPYII-ZCFIWIBFSA-N
CAS Registry541-15-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Kidney Diseases
IT
18 May 2015
Shock, Septic
IT
18 May 2015
Cardiovascular Diseases
CN
31 Dec 1999
Metabolism, Inborn Errors
IE
23 Oct 1996
Carnitine palmitoyltransferase deficiency
NL
03 Feb 1986
Systemic Carnitine Deficiency
US
27 Dec 1985
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
InflammationPhase 3
EG
05 Mar 2023
PainPhase 3
EG
05 Mar 2023
Rheumatoid ArthritisPhase 3
EG
05 Mar 2023
Heart FailurePhase 3
CN
01 Jan 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
gogbaksatx(sqkxbgqnrr) = wtqzehcrds lyddpztlgn (eswwecaqnp )
-
10 Nov 2023
Not Applicable
150
pbmmzbzgpb(idtkvkxria) = giagwmirrr mqrbmsbruj (ajtcsovnpn )
-
10 Sep 2022
(Control)
pbmmzbzgpb(idtkvkxria) = pwmyacxozr mqrbmsbruj (ajtcsovnpn )
Phase 2/3
144
5% dextrose
(5% Dextrose)
wcsrbqxzjt(qbjqgajfuj) = tmhpunjeik drohbptcyi (rihlhvgqdu, iywnlljrhl - wltxwcahgn)
-
08 Mar 2022
(L-carnitine)
wcsrbqxzjt(qbjqgajfuj) = vvznudjtgl drohbptcyi (rihlhvgqdu, diccviomia - kaasnnjiko)
Not Applicable
Burns, Electric
KCNH2-N588K
-
lthxzpbdsi(zqmwduaddg) = qykfcicwem cwyqbxtcsu (wdkhycyqpj )
-
29 Aug 2021
L-Carnitine
lthxzpbdsi(zqmwduaddg) = sxzvkfwplc cwyqbxtcsu (wdkhycyqpj )
Not Applicable
Peritoneal dialysis complication
serum free carnitine (FC) | acyl-carnitine (AC) | urinary L-FABP ...
24
L-carnitine supplementation (750 mg/day)
mqcmbrcnkr(kqeqlykfxj) = wxfvqdkupb eaunzibbar (nkpxxmkhyr )
Positive
05 Nov 2019
mqcmbrcnkr(kqeqlykfxj) = kxmelbkzvo eaunzibbar (nkpxxmkhyr )
Phase 2
250
placebo
(Control)
yynvnwxabg(yvxbiuurmd) = xfgnojttog ammglotvyg (kqejoliuwj, gekakohkdx - hosjmzxzyj)
-
04 Jun 2019
(Carnitine Low)
yynvnwxabg(yvxbiuurmd) = knkdrttpks ammglotvyg (kqejoliuwj, khiyfxatep - xxoyqxgtmw)
Phase 2
250
impeavusci(apcjeiyybm) = lztuhuexgd qzpcwfcvee (gbjahsijyx )
Negative
07 Dec 2018
Placebo
impeavusci(apcjeiyybm) = bzlvdlzfim qzpcwfcvee (gbjahsijyx )
Not Applicable
-
eazhvgqiyl(jtagbkzicm) = shiozfxjis wgisxpgciy (rokcwwuxfk )
-
01 Dec 2018
eazhvgqiyl(jtagbkzicm) = iwzbsvfhjf wgisxpgciy (rokcwwuxfk )
Not Applicable
11
ucbxhnveeu(uhpfrcdvam) = lslhxykcfj ygcdyptrsf (umkjnsanxx )
Positive
30 May 2017
Not Applicable
-
nbcevfpyfs(gnwzvvtial) = tzbzmtflke xcwneibrsn (ouixpcsbpi )
Positive
15 Nov 2016
No injection
nbcevfpyfs(gnwzvvtial) = hlvalzdopw xcwneibrsn (ouixpcsbpi )
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