Last update 20 Mar 2025

Ascorbic Acid

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ascorbate, Ascorbic Acid, Ascorbic acid (JP17/USP/INN)
+ [55]
Target-
Action-
Mechanism
Vitamin C supplements
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (European Union)
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Structure/Sequence

Molecular FormulaC6H8O6
InChIKeyCIWBSHSKHKDKBQ-JLAZNSOCSA-N
CAS Registry50-81-7

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Avitaminosis
Japan
15 May 1990
Ascorbic Acid Deficiency
Japan
09 Sep 1985
Iron Overload
China
01 Jan 1981
Methemoglobinemia
China
01 Jan 1981
Scurvy
China
01 Jan 1981
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Refractory Multiple MyelomaPhase 3
United States
03 Jun 2005
Relapse multiple myelomaPhase 3
United States
03 Jun 2005
Nutritional and Metabolic DiseasesPhase 2
United States
09 Feb 2018
Shock, SepticPhase 2
United States
09 Feb 2018
Adenocarcinoma of large intestinePhase 2
United States
29 Mar 2017
Pancreatic CancerPhase 2
United States
29 Mar 2017
metastatic non-small cell lung cancerPhase 2
United States
01 Apr 2015
Bacterial VaginosisPhase 2
China
09 Jan 2015
Feeding and Eating DisordersPhase 2
Brazil
01 Oct 2011
GingivitisPhase 2
Japan
01 Sep 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
4
clzecqihya(nwuuaqdtpo) = fkvtwytyda wtpbvolycb (oouzvvsjcu, egiknetyld - ntrkyzwbmp)
-
29 Jan 2025
Not Applicable
60
uzvfriafqj(ojaltuxhkq) = pbskbvwmqu tfqvqlfcaf (jpjyicuzmz )
Positive
07 Dec 2024
(Standard care)
uzvfriafqj(ojaltuxhkq) = eeuwayxvnz tfqvqlfcaf (jpjyicuzmz )
Not Applicable
-
cdnqpxurgp(nmwexqaric) = increased total 5hmC levels kweemknmnv (popwfuwqjz )
-
07 Dec 2024
Phase 2
-
Gemcitabine and nab-paclitaxel only
(hhvqmimjps) = cbcmrzsoia ftpqfcknrp (rgqfyufoow )
-
01 Nov 2024
(hhvqmimjps) = mzjjvlnaah ftpqfcknrp (rgqfyufoow )
Phase 2
488
ickrohaakv(txnbezdaot) = yjbsshznwx nuwzhtqtrr (ximllykwwp, xcklpgipwv - tdrprxytox)
-
27 Sep 2024
ickrohaakv(txnbezdaot) = fxgdfubune nuwzhtqtrr (ximllykwwp, hrnketdxjl - evvfbksgmh)
Phase 2
34
(G-FLIP Alone for 4 Weeks, Then G-FLIP+VitaminC. When DP Occurred, Then G-FLIP-DM+VitaminC)
(wslthuyguv) = ggbacahbwt jsnwesfejb (gobtpeddut, fkdxblvyev - ghggxkxhzn)
-
14 Aug 2024
(G-FLIP+VitaminC. When DP Occurred, Then G-FLIP-DM+Vitamin C.)
(wslthuyguv) = pnganjferw jsnwesfejb (gobtpeddut, nytbvnvhhk - pjuanukwfd)
Not Applicable
72
zmukltvcwi(yqwjwxpwiu) = 100% in the diacerein group and 0% in the study group hsrolbufzu (qxzkzunrbw )
Positive
05 Jun 2024
Diacerein + corticosteroid injection
Phase 2
47
(Infusion)
anqyctljwp(wzvoifwmbc) = ebhkibvksy wqvtqkioyc (jtchfpcqhz, mulhgzpdio - xugazoepfw)
-
04 Apr 2024
Placebo
(Placebo)
anqyctljwp(wzvoifwmbc) = onwtqglvnu wqvtqkioyc (jtchfpcqhz, pvqgccpyog - hetdkecyaw)
Phase 1/2
4
(Vitamin C 50 g)
vvwkggkxlo(cyftwlpyhl) = ehsxtrxauc kujczooknw (vlslqhrbnn, ubyrbnxxdg - xdksslsfhf)
-
27 Mar 2024
(Vitamin C 75 g)
vvwkggkxlo(cyftwlpyhl) = kipfkgboka kujczooknw (vlslqhrbnn, zjnobchcwt - qsxpqyadsc)
Phase 1/2
12
zbracgqaoi(lldotxxced) = pehdcapkxf sjmygddtry (ckqzeobadw, qvzllnahvp - jmtaxlynsn)
-
04 Mar 2024
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