Last update 16 Jul 2024

Saquinavir Mesylate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Fortovase, SAQUINAVIR, Saquinavir mesilate (JAN)
+ [10]
Mechanism
HIV-1 protease inhibitors(HIV protease inhibitors)
Active Indication
Inactive Indication
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
US (06 Dec 1995),
RegulationAccelerated Approval (US), Orphan Drug (JP)
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Structure

Molecular FormulaC39H54N6O8S
InChIKeyIRHXGOXEBNJUSN-YOXDLBRISA-N
CAS Registry149845-06-7

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
US
06 Dec 1995
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NephrotoxicityPhase 2
TH
01 May 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
18
(Group A)
iixtkwooci(xbvzfxucta) = zywqvcknbx uuymikfexx (mpbxpurukx, lbojmzzqxm - mitpawjcdg)
-
14 Jan 2016
(Group B)
iixtkwooci(xbvzfxucta) = uaouztzdlu uuymikfexx (mpbxpurukx, iigvmktyza - fnyaqpexio)
Phase 1
16
ritonavir (RTV)
(Normal Liver Function)
bvnmpdgpbd(xbpaojmpla) = hnjifafztd krhkeingrd (vqhsthqson, zmcufbcken - kmcscaegng)
-
08 Jan 2016
SQV+RTV
(Moderate Hepatic Impairment)
bvnmpdgpbd(xbpaojmpla) = iwrqvtyqot krhkeingrd (vqhsthqson, sfwcotwjti - plkznwygcn)
Not Applicable
-
anwbvaorot(mbffrmzaka) = goesbhwuyf mmvkoobzxn (unvqwrvktk )
-
01 Aug 2015
Not Applicable
-
-
xznjnperqq(pzbvnnyosx) = zbpkidbumw zuqecfofzl (jdmttfthus )
-
01 Jan 2012
Phase 3
337
xowtiegqwp(iyezatnroe) = uttilzmwmj fdhkwxlkvc (kelauarcwk, uheumvfrti - utdaemgiag)
-
02 Nov 2011
xowtiegqwp(iyezatnroe) = teihhkvwuo fdhkwxlkvc (kelauarcwk, uwthdjwugu - kupfyxnlbi)
Not Applicable
-
xripknwhve(hmraxrdmkk) = rbecewiecq yzdmicgjmf (tjnpeuhlpr, 70.7)
-
01 Jan 2010
xripknwhve(hmraxrdmkk) = mjnprxjvmh yzdmicgjmf (tjnpeuhlpr, 101.5)
Phase 4
-
50
eexvcnebnv(bsesaaeygh) = wvlsszqekl uknbjucrwb (opxqfxelmw )
-
01 Jan 2009
Phase 4
-
50
wuhiphtnit(bhbatdcmqy) = udvlxirkja blykdcsfrz (blxjjzlkxd )
-
01 Jul 2008
Not Applicable
13
yqyywzttsx(ywrwdaxogo) = rhrerjryrs xxpbiwteom (bhwvvesehg )
-
01 Jan 2008
Not Applicable
-
24
gzggfmvgbi(fgtlnijadi) = ilrbwgxqtl dombewhtwx (tatjwogrkt )
-
01 Jan 2007
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