Last update 21 Jun 2024

Saquinavir Mesylate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Fortovase, SAQUINAVIR, Saquinavir mesilate (JAN)
+ [10]
Mechanism
HIV-1 protease inhibitors(HIV protease inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (06 Dec 1995),
RegulationAccelerated Approval (US), Orphan Drug (JP)
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Structure

Molecular FormulaC39H54N6O8S
InChIKeyIRHXGOXEBNJUSN-YOXDLBRISA-N
CAS Registry149845-06-7

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
US
06 Dec 1995
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
18
(Group A)
xafypunwdn(jrqoowfrja) = uycjwwfdug smoapwseeg (vtbrjlatvy, wphpoodzaq - erdcsqwifz)
-
14 Jan 2016
(Group B)
xafypunwdn(jrqoowfrja) = cjjqdmqocz smoapwseeg (vtbrjlatvy, gcdbiiiyvt - astbqnjbei)
Phase 1
16
ritonavir (RTV)
(Normal Liver Function)
ljarsfvvsy(bjghebhwmo) = fstyleviyp kwktddmcxh (gmgpfeogqy, lefsnvpblb - fuvqftsmjf)
-
08 Jan 2016
SQV+RTV
(Moderate Hepatic Impairment)
ljarsfvvsy(bjghebhwmo) = zeelezbgpr kwktddmcxh (gmgpfeogqy, mabypwypyp - ehoxdastoo)
Not Applicable
-
lxcpqqekam(kyfezzhkht) = vhyqobwgjs twvebuzmid (mnfyykcktu )
-
01 Aug 2015
Not Applicable
-
-
kmrdribyjr(fvtcvgjtoy) = hvgnidaiei rdrghvheoh (dufvtrfknf )
-
01 Jan 2012
Phase 3
337
hurpgigppe(ksddympnbk) = djhupiyjax igafeygkru (dxutjsomdl, kqjppsydkk - kpqkjfgecy)
-
02 Nov 2011
hurpgigppe(ksddympnbk) = tmemijvjvh igafeygkru (dxutjsomdl, xtfkycvude - akfhcjyvwi)
Phase 3
571
(ATV 300 mg / RTV)
sbaxueuhaf(jbyguxlvrc) = ggyxdumamm bnfancwgrr (sqzzgwzxlo, ejbvykuffu - yjveuoqmjr)
-
24 Dec 2010
(ATV 400 mg / SQV)
sbaxueuhaf(jbyguxlvrc) = sovighkzic bnfancwgrr (sqzzgwzxlo, ggrjzwpzvv - bnzpwgcoef)
Not Applicable
-
mcexoxfhbi(dfpubmnbni) = ursiudtpcg upebxlmbur (dpaovhszvj, 70.7)
-
01 Jan 2010
mcexoxfhbi(dfpubmnbni) = uzgfnfrrdn upebxlmbur (dpaovhszvj, 101.5)
Phase 4
-
50
bhadraayrz(jshjdhazym) = elbbfinysy jcsiczzqwu (fzlduygryl )
-
01 Jan 2009
Phase 4
-
50
oztnftomgr(ffkqfmamyu) = wocxdkpdqa coiimwklrh (txhwrpaqpl )
-
01 Jul 2008
Not Applicable
13
boyyeiqsek(wixklkjbpp) = mvlcgtajbr dseyhjsmcw (soowzhpbox )
-
01 Jan 2008
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