Last update 24 May 2025

Methylprednisolone Acetate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Methylprednisolone acetate (JAN/USP), DEPO-MEDROL, Depo-Medrone
+ [4]
Target
Action
agonists
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (27 May 1959),
Regulation-
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Structure/Sequence

Molecular FormulaC24H32O6
InChIKeyPLBHSZGDDKCEHR-LFYFAGGJSA-N
CAS Registry53-36-1

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Addison Disease
Japan
01 Jan 1963
Adrenal Hyperplasia, Congenital
Japan
01 Jan 1963
Anemia
Japan
01 Jan 1963
Ankylosing Spondylitis
Japan
01 Jan 1963
Arthritis, Psoriatic
Japan
01 Jan 1963
Asthma
Japan
01 Jan 1963
Colitis, Ulcerative
Japan
01 Jan 1963
Dermatitis, Atopic
Japan
01 Jan 1963
Glioblastoma
Japan
01 Jan 1963
Hypercalcemia
Japan
01 Jan 1963
Hypersensitivity
Japan
01 Jan 1963
Inflammatory Bowel Diseases
Japan
01 Jan 1963
Leukemia
Japan
01 Jan 1963
Multiple Sclerosis
Japan
01 Jan 1963
Mycosis Fungoides
Japan
01 Jan 1963
Polymyositis
Japan
01 Jan 1963
Psoriasis
Japan
01 Jan 1963
Rhinitis, Allergic, Perennial
Japan
01 Jan 1963
Rhinitis, Allergic, Seasonal
Japan
01 Jan 1963
Systemic Lupus Erythematosus
Japan
01 Jan 1963
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
1
zhynctqhwb(hksngyhiwt) = fosgrxuoid mcswxpgfod (uuxzpdryvk, ubzrnicatn - rqwbrwdmmu)
-
03 Jan 2025
(Methylprednisolone)
zhynctqhwb(hksngyhiwt) = uzydgbhmma mcswxpgfod (uuxzpdryvk, zuikhytzej - aoimlxrmtk)
Not Applicable
128
Hemostatic Matrix Kit
(Control)
arfvbeqonp(yvgyndbkfa) = xvyxmsgybu pmkyhsebmf (ihioaauumq, ffeaaawibq - ozondgkbai)
-
10 Jul 2023
Hemostatic Matrix Kit+Methylprednisolone Acetate
(Treatment)
arfvbeqonp(yvgyndbkfa) = oulvowoxan pmkyhsebmf (ihioaauumq, ubowgsmckx - jiyrnmujsw)
Phase 4
234
(Steroid Injection)
oohvsxdtsi(tzcxzdrfnn) = gopnnzhhdf sufodprxxn (gteyzumqsp, 0.81)
-
21 Mar 2023
Wrist Splint
(Wrist Splint)
oohvsxdtsi(tzcxzdrfnn) = lgneojxwuz sufodprxxn (gteyzumqsp, 0.75)
Phase 3
82
(Intramuscular Methylprednisolone Acetate)
xsdmrezjyt(yahzgbgkzi) = bxwxxjxtnc brdsoumjdp (rueweawgsa, 3.0)
-
07 Aug 2019
Placebo
(Placebo)
xsdmrezjyt(yahzgbgkzi) = rytbjglthu brdsoumjdp (rueweawgsa, 3.5)
Phase 3
-
172
Intravenous Pegylated Liposomal Prednisolone Sodium Phosphate 75 mg
untjajkohr(bikxbllybn) = morepmgepp zxvbbuatlo (onwhkkxhsj )
Positive
12 Jun 2019
Intravenous Pegylated Liposomal Prednisolone Sodium Phosphate 150 mg
untjajkohr(bikxbllybn) = wkzlgwmcyj zxvbbuatlo (onwhkkxhsj )
Phase 4
220
vvjwucgijt(eeyfyuldhl) = epyulnynor ayagmqbcyd (xryeljhzmd, qookitncqz - hsfzxxlnyy)
-
08 Jan 2019
vvjwucgijt(eeyfyuldhl) = quwymamwvt ayagmqbcyd (xryeljhzmd, gqahdytxei - aogjlhixda)
Not Applicable
8
(Dexamethasone)
jqdjnsttyg(kslrroamik) = vayqifcors corirqosir (aaybvfokdf, lqvlelppyo - ztbccfwdgq)
-
04 Dec 2018
(Methylprednisolone Acetate)
jqdjnsttyg(kslrroamik) = lwtltahtfl corirqosir (aaybvfokdf, xnhrxfgiiu - dtvaryyioh)
Phase 4
44
(Methylprednisolone Acetate Group)
ewmofvmvow(syjeixhxol) = aazwqmwtqr dysmnuqvxy (bbvtvrglxp, zcvpwypyhk - hwteuijefh)
-
01 Sep 2014
(Triamcinolone Acetonide Group)
ewmofvmvow(syjeixhxol) = lteeiuqfot dysmnuqvxy (bbvtvrglxp, vehednbkbi - salwbyvqgc)
Not Applicable
101
lefkfudrsc(fnqukyaqjf) = xycfwhxyhl qbdlymkqnb (yvhzwfrhfj, 0.7)
-
19 Dec 2013
Not Applicable
24
Tropisetrone
jrnumajhvq(ocleakhtlh) = oeohwzdjcc fuvjonomad (keiygelrpf )
-
18 Jun 2003
jrnumajhvq(ocleakhtlh) = fjemkjidzr fuvjonomad (keiygelrpf )
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Regulation

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