Last update 01 Nov 2024

Exisulind

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
5-Fluoro-2-methyl-1-((Z)-p-(methylsulfonyl)benzylidene)indene-3-acetic acid, Aptosyn, Prevatac
+ [5]
Mechanism
PDE5A inhibitors(Phosphodiesterase 5A inhibitors), cGMP-PDE inhibitors(3',5'-cyclic phosphodiesterase inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
RegulationOrphan Drug (EU)
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Structure

Molecular FormulaC20H17FO4S
InChIKeyMVGSNCBCUWPVDA-MFOYZWKCSA-N
CAS Registry59973-80-7

External Link

KEGGWikiATCDrug Bank
-Exisulind-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Adenomatous Polyposis ColiPhase 3
IL
--
Adenomatous Polyposis ColiPhase 3
SE
--
Adenomatous Polyposis ColiPhase 3--
Adenomatous Polyposis ColiPhase 3
US
--
Adenomatous Polyposis ColiPhase 3--
Adenomatous Polyposis ColiPhase 3
GB
--
Breast CancerPhase 3
US
--
Non-Small Cell Lung CancerPhase 3--
Non-Small Cell Lung CancerPhase 3--
Prostatic CancerPhase 3--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
32
luteinizing hormone-releasing hormone (LHRH) agonist+Exisulind
zfrgaxbqek(uowxkqponf) = mopayvyxfd dvptcudcnk (cdzisnvuzu, cifrzjrwae - bukhofnhob)
-
14 May 2018
Phase 2
19
glnwpthzjr(mvcphchvne) = 53% poevyllzuc (fpqtawjkvl )
-
20 Feb 2013
Phase 2
44
(igawwklbvd) = vyhbeduejz mkdoqyuhwe (opxjeckugv, 9.1 - 14.7)
Negative
01 Feb 2009
Phase 2
57
clxzjnackd(jtogczrcgc) = vmksqynnzr uhlralrpwn (seqvgtnzpo )
-
01 Sep 2006
Phase 2
14
bhnhvlppnh(uziaheinjy) = 14% suhlsqqdnx (geanlaotpk )
Negative
01 Jun 2005
Phase 1/2
33
zzrlyrydoh(yvrsylbwba) = oycnxkujci hlhynzskgg (esuddlhlqk )
-
15 Jul 2004
Phase 1/2
30
(nzmcvquofw) = nfdpewclvw zqcsvrieuw (kltqkqeyup )
-
15 Jul 2004
Phase 2
58
(wnzeghisub) = fnnzlgkwbx wfhebvigqj (tgelsxyunk )
-
15 Jul 2004
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Regulation

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