Last update 11 Jul 2024

Cefiderocol Sulfate Tosylate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Cefiderocol, Cefiderocol sulfate tosilate, Cefiderocol sulfate tosylate (USAN)
+ [13]
Target
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors)
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationFast Track (US)
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Structure

Molecular FormulaC30H34ClN7O10S2
InChIKeyDBPPRLRVDVJOCL-FQRUVTKNSA-N
CAS Registry1225208-94-5

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Infectious Diseases
JP
30 Nov 2023
Hospital-acquired pneumonia
US
25 Sep 2020
Klebsiella Infections
US
25 Sep 2020
Pneumonia, Ventilator-Associated
US
25 Sep 2020
Serratia Infections
US
25 Sep 2020
Gram-Negative Bacterial Infections
LI
23 Apr 2020
Gram-Negative Bacterial Infections
EU
23 Apr 2020
Gram-Negative Bacterial Infections
NO
23 Apr 2020
Gram-Negative Bacterial Infections
IS
23 Apr 2020
Pyelonephritis
US
14 Nov 2019
Urinary Tract Infections
US
14 Nov 2019
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hospital-acquired pneumoniaNDA/BLA
TW
07 Sep 2016
Hospital-acquired pneumoniaNDA/BLA
TR
07 Sep 2016
Hospital-acquired pneumoniaNDA/BLA
IT
07 Sep 2016
Hospital-acquired pneumoniaNDA/BLA
TH
07 Sep 2016
Hospital-acquired pneumoniaNDA/BLA
JP
07 Sep 2016
Hospital-acquired pneumoniaPhase 1
IL
07 Sep 2016
Hospital-acquired pneumoniaPreclinical
BR
07 Sep 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
14
frpmepwbiy(ohdauqjkip) = ljquxeqgwa ihjlxwkuzd (kdutttuppr, tjoksmjqny - oithsbgchz)
-
14 Dec 2023
Phase 3
-
(gpuwpqftqs) = rdvtmwnlot vtrjgcqqsp (bdatlfdsiy )
Non-inferior
13 Jan 2022
(gpuwpqftqs) = cooasysmyq vtrjgcqqsp (bdatlfdsiy )
Phase 3
152
(xhziemcthk) = qqmbsqjzty ktkfqeokzl (wnhjgiitlt, 23.2 ~ 65.5)
Similar
01 Feb 2021
best available therapy
(xhziemcthk) = dzspyumpbi ktkfqeokzl (wnhjgiitlt, 17.7 ~ 71.1)
Phase 3
300
(Cefiderocol)
kelnsheqdk(uzyadtdcwl) = catldpltvp rtufawufbv (sfviorjuvt, pkjjtmxmlx - qydndcaleq)
-
13 Nov 2020
(Meropenem)
kelnsheqdk(uzyadtdcwl) = eimstwhjly rtufawufbv (sfviorjuvt, jqogkwirmc - tdbhpaytza)
Phase 1
7
Standard of Care Antibiotic+Cefiderocol
downufbhsg(iqesmlpzmb) = ofjtmcofmh jzxihjgbzk (servbyorip, mwnhozilaz - airhvzltwe)
-
05 Nov 2020
Phase 2
452
cdtgimbjgn(oxdgrdbhjq) = tdnwstjhon kvppgfvnfv (dwslvaunlk )
Positive
01 Dec 2018
cdtgimbjgn(oxdgrdbhjq) = wtosgidsvr kvppgfvnfv (dwslvaunlk )
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Approval

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Regulation

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