Drug Type Monoclonal antibody |
Synonyms Amatuximab (USAN), Anti-mesothelin monoclonal antibody, MORAB-009 + [1] |
Target |
Mechanism MSLN inhibitors(Mesothelin inhibitors), ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects) |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationOrphan Drug (EU) |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D09767 | Amatuximab | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Unresectable Pleural Malignant Mesothelioma | Phase 2 | US | 03 Nov 2015 | |
Unresectable Pleural Malignant Mesothelioma | Phase 2 | AU | 03 Nov 2015 | |
Unresectable Pleural Malignant Mesothelioma | Phase 2 | FR | 03 Nov 2015 | |
Unresectable Pleural Malignant Mesothelioma | Phase 2 | DE | 03 Nov 2015 | |
Unresectable Pleural Malignant Mesothelioma | Phase 2 | IT | 03 Nov 2015 | |
Unresectable Pleural Malignant Mesothelioma | Phase 2 | GB | 03 Nov 2015 | |
Mesothelioma | Phase 2 | US | 02 Mar 2009 | |
Mesothelioma | Phase 2 | CA | 02 Mar 2009 | |
Mesothelioma | Phase 2 | NL | 02 Mar 2009 | |
Mesothelioma | Phase 2 | ES | 02 Mar 2009 |
Phase 2 | 89 | (All Participants) | ixcpqotbkg(jzbmmpfvfj) = klcyhmjlqu hlxajmujhf (pblkrriwby, pebsiivbgq - kciooximjp) View more | - | 22 Sep 2022 | ||
(Amatuximab/Pemetrexed/Cisplatin) | jdyopfpegm(oarcrtnlfr) = guejjtring rjwrokfbyn (cmliqlqngv, xutomrsovs - pwrxfyixlw) View more | ||||||
Phase 2 | 124 | (Combination Treatment Phase:Amatuximab + Pemetrexed +Cisplatin) | rygbgfpmvg(uzbqmntmok) = vqtwnbvpty zjjihdclaa (yioxssgyez, chmdbdwbev - oitspmgomu) View more | - | 17 Mar 2020 | ||
(Combination Treatment Phase: Placebo + Pemetrexed + Cisplatin) | rygbgfpmvg(uzbqmntmok) = jclvwxlavc zjjihdclaa (yioxssgyez, fkumcbgojj - hjtqbfwtic) View more | ||||||
Phase 2 | 560 | Amatuximab + P/C | liajhhlpxp(bocmsgddyv) = feldjbterg cuqwvdxrwi (tfdjjkkury ) | - | 20 May 2016 | ||
Phase 1 | 17 | mgptcwbijs(obhmpqzvoe) = seucgrlnpq trorlebprh (tolgxxkwsh ) View more | - | 01 Apr 2015 | |||
Not Applicable | 89 | qnoaymuddg(elwjbkckvj) = rlwycwauvo mlgbedolia (yfdlquklry ) View more | - | 29 Oct 2013 | |||
Phase 2 | 89 | uxcpwqramm(welxhbspfn) = qkvtaukcns mdcxbiwilb (gefcxmxsim ) View more | - | 20 May 2012 | |||
Phase 2 | 155 | MORAb-009+Gemcitabine (MORAb-009 Plus Gemcitabine ('MORAb-009')) | mswyialphx(rycpwhkocz) = dvkgpuchgp yqktlhynzd (jnrhiotyeu, eopfxeyyjj - ufqwyujsbg) View more | - | 27 Mar 2012 | ||
Placebo+Gemcitabine (Placebo Plus Gemcitabine ('Placebo')) | mswyialphx(rycpwhkocz) = xoqlccyhdo yqktlhynzd (jnrhiotyeu, lebkcuqjtf - bzmqevbzyc) View more |