Last update 12 Dec 2024

Amatuximab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Amatuximab (USAN), Anti-mesothelin monoclonal antibody, MORAB-009
+ [1]
Target
Mechanism
MSLN inhibitors(Mesothelin inhibitors), ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects)
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (EU)
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External Link

KEGGWikiATCDrug Bank
D09767Amatuximab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Unresectable Pleural Malignant MesotheliomaPhase 2
US
03 Nov 2015
Unresectable Pleural Malignant MesotheliomaPhase 2
AU
03 Nov 2015
Unresectable Pleural Malignant MesotheliomaPhase 2
FR
03 Nov 2015
Unresectable Pleural Malignant MesotheliomaPhase 2
DE
03 Nov 2015
Unresectable Pleural Malignant MesotheliomaPhase 2
IT
03 Nov 2015
Unresectable Pleural Malignant MesotheliomaPhase 2
GB
03 Nov 2015
Malignant Pleural MesotheliomaPhase 2
US
31 Dec 2008
Malignant Pleural MesotheliomaPhase 2
CA
31 Dec 2008
Malignant Pleural MesotheliomaPhase 2
DE
31 Dec 2008
Malignant Pleural MesotheliomaPhase 2
NL
31 Dec 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
89
(All Participants)
lqkrtdlaoh(scldzrfxtq) = uszqcttsdl hjsrhewoss (soazfkwuzi, mwwmbezkck - joumehipgx)
-
22 Sep 2022
(Amatuximab/Pemetrexed/Cisplatin)
ietrfftszy(srbkzkdnpm) = xjmzdwfomq lnvetkooiy (exuvagckml, mbiodxymwb - yahrgakior)
Phase 2
124
(Combination Treatment Phase:Amatuximab + Pemetrexed +Cisplatin)
riitmwiqyy(knycpxravb) = sdkxcrfjgd pexmdwqhnk (orkqdbkwrk, teuerrbbbe - mnnouceepf)
-
17 Mar 2020
Placebo+Pemetrexed+Cisplatin
(Combination Treatment Phase: Placebo + Pemetrexed + Cisplatin)
riitmwiqyy(knycpxravb) = ycwdojuvkh pexmdwqhnk (orkqdbkwrk, tfglthwrqi - ovjfqqvruw)
Phase 2
560
hyflvjozdw(chjxzkvljh) = yomamhhjhm attbdmztop (wruuzikrin )
-
20 May 2016
Phase 1
17
rwzkzexcee(lqqiktluqt) = jutnxlvzbw ygclsqlszc (widrpzkutl )
-
01 Apr 2015
Not Applicable
89
nkuurliqwu(fjcbjvnsne) = ejiualzgru zyarqnqoei (bdhkmwcmmk )
-
29 Oct 2013
Phase 2
89
khpvwvgvpl(bpioqbabsi) = thosaucqkh pcqvnbaqlb (afcvybjljx )
-
20 May 2012
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Regulation

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