Last update 06 Dec 2024

Piperaquine Phosphate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Piperaquine, Tlinsuangpaiqin, Trochisci Piperazini Phoshatis
+ [5]
Target
Mechanism
CYP3A4 inhibitors(Cytochrome P450 3A4 inhibitors)
Therapeutic Areas
Active Indication
Inactive Indication-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date-
Regulation-
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Structure

Molecular FormulaC29H35Cl2N6O4P
InChIKeyKATNPMSTHHZOTK-UHFFFAOYSA-N
CAS Registry85547-56-4

External Link

KEGGWikiATCDrug Bank
-Piperaquine Phosphate-

R&D Status

10 top approved records.
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
6
Administration of the malaria inoculum+Piperaquine Phosphate 480 mg
jrxvhmvdrk(wrlfcmfccp) = erymfavffr ikamkhrcth (nqqmfemzou, ewtjgcbcrx - aqnzaztnfn)
-
26 May 2020
Phase 2/3
448
(A) Artefenomel 800mg: Piperaquine 640mg)
amlhbyoxww(qgnnlvtgla) = rfxwkbbkxc cdwowevcqq (nqmdekcfwq, uoyqvdrves - znalzwbonq)
-
30 Jan 2017
(B) Artefenomel 800mg: Piperaquine 960mg)
amlhbyoxww(qgnnlvtgla) = haodcebplx cdwowevcqq (nqmdekcfwq, wadpeytevm - psuxfpherf)
Phase 1
48
PQP+OZ439 + TPGS
(Regimen A: OZ439 + TPGS and PQP)
vobpaswaoa(prayqszgvz) = agbkjkuamp asdsjcneqn (diebrddkeg, vxwhgqznlq - nucsagbjwy)
-
14 Jan 2016
OZ439 Prototype 1+PQP
(Regimen B: OZ439 Prototype 1 and PQP - 110mL)
vobpaswaoa(prayqszgvz) = khvlirxeeq asdsjcneqn (diebrddkeg, yamgnwkaoe - rkkxpkiifj)
Phase 1
55
(Treatment A: 1440mg PQP Tablets & 800mg OZ439 + TPGS)
tgthdfwafu(krajpwkzio) = prytqjjugg cainhzpnpp (agmzcuihsg, gcofknstcw - lryvnqfqxr)
-
21 Apr 2015
(Treatment B: 960mg PQP Tablets & 800mg OZ439 + TPGS)
tgthdfwafu(krajpwkzio) = dymswuxddf cainhzpnpp (agmzcuihsg, jjuofbekkf - kpygtdxgfh)
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Regulation

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