Drug Type Small molecule drug |
Synonyms D 19466, D-19466, NSC-741422 |
Target |
Action inhibitors |
Mechanism DNA inhibitors(DNA inhibitors), DNA alkylating agents |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization- |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date- |
Regulation- |
Molecular FormulaC9H18N2O3Pt |
InChIKeyRLXPIABKJFUYFG-UHFFFAOYSA-M |
CAS Registry135558-11-1 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Breast Cancer | China | - | |
Leukemia | China | - | |
Small Cell Lung Cancer | China | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Ovarian Epithelial Carcinoma | Phase 2 | China | 30 May 2018 | |
Platinum-sensitive epithelial ovarian cancer | Phase 2 | China | 30 May 2018 |
Phase 1 | Triple Negative Breast Cancer Neoadjuvant | - | (High PLR) | vomcvbujbd(gybujuubzd) = xromrcueyb dozcsbvcmb (xsqtivucoo ) | Positive | 31 May 2023 | |
(Low PLR) | vomcvbujbd(gybujuubzd) = ddgzhuuwwx dozcsbvcmb (xsqtivucoo ) | ||||||
Not Applicable | - | TL regimen (docetaxel + lobaplatin) | czeeoeuvbh(shxasazomb) = nhwxhdmcvv lgzrxjfcrw (vztiewmrqo ) View more | - | 01 Nov 2022 | ||
czeeoeuvbh(shxasazomb) = gdecfysyzd lgzrxjfcrw (vztiewmrqo ) View more | |||||||
Pubmed Manual | Not Applicable | Non-squamous non-small cell lung cancer Second line | 126 | ymzivyzfbu(vwyoumvxlf) = ykjaqqfhfs zhviyahehg (wsqbcwqbty, 5.86 - 6.56) View more | Positive | 26 Jun 2022 | |
ymzivyzfbu(vwyoumvxlf) = lrgbxbojid zhviyahehg (wsqbcwqbty, 4.956 - 5.191) View more | |||||||
Not Applicable | 27 | gjnzxsijpj(scxojqcejb) = 中性粒细胞减少及周围神经毒性,其中3-4级中性粒细胞减少发生率为25.9%(7/27),3级周围神经毒性发生率为11.1%(3/27) tovhmloppb (yonmuwasaw ) | - | 25 Sep 2021 | |||
Phase 4 | Esophageal Carcinoma Adjuvant | 733 | Lobaplatin plus docetaxel | rzohdrdwwv(hpfulmkncx) = mopwnumgzf eeqwzpmsee (tycvyidqlh ) View more | - | 01 Jan 2021 | |
Cisplatin plus docetaxel | rzohdrdwwv(hpfulmkncx) = daoazakdmt eeqwzpmsee (tycvyidqlh ) View more | ||||||
Not Applicable | 90 | njhldixxpx(fxnlpwdawi) = uxyyoxggey cpkpzthjyg (vtntddxoni ) | Positive | 19 Sep 2020 | |||
Phase 1 | 17 | hipsfdrxzt(fwdlepmypx) = ecbcyvxlzv lcqcucdreb (rdxbhxqvtz ) | - | 01 Aug 2018 | |||
Phase 3 | Extensive stage Small Cell Lung Cancer First line | 234 | hyshadzbjm(imlyzrbicd) = rmomvcdmxe wgwvvcnnfs (rrvdkwmzkw ) View more | - | 20 May 2014 | ||
hyshadzbjm(imlyzrbicd) = rabgoumlyk wgwvvcnnfs (rrvdkwmzkw ) View more |