Drug Type Small molecule drug |
Synonyms D 19466, D-19466, NSC-741422 |
Target |
Mechanism DNA inhibitors(DNA inhibitors), DNA alkylating agents |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization- |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date- |
Regulation- |
Molecular FormulaC9H18N2O3Pt |
InChIKeyRLXPIABKJFUYFG-UHFFFAOYSA-M |
CAS Registry135558-11-1 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Breast Cancer | CN | - | |
Leukemia | CN | - | |
Small Cell Lung Cancer | CN | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Ovarian Epithelial Carcinoma | Phase 2 | CN | 30 May 2018 | |
Platinum-sensitive epithelial ovarian cancer | Phase 2 | CN | 30 May 2018 |
Phase 1 | Triple Negative Breast Cancer Neoadjuvant | - | (High PLR) | fmvnclqolj(zbqngftznq) = czedehzgpu ohzijdmzwj (htphimnnpj ) | Positive | 31 May 2023 | |
(Low PLR) | fmvnclqolj(zbqngftznq) = iejrpoqnib ohzijdmzwj (htphimnnpj ) | ||||||
Pubmed Manual | Not Applicable | Non-squamous non-small cell lung cancer Second line | 126 | mzumgwsyhy(ofrycecifb) = mbmzbyywwu wpaeahyocv (cxkrcopddk, 5.86 - 6.56) View more | Positive | 26 Jun 2022 | |
mzumgwsyhy(ofrycecifb) = tysiyjyxzh wpaeahyocv (cxkrcopddk, 4.956 - 5.191) View more | |||||||
Not Applicable | 27 | wgxabmrtck(panhtwvzyr) = 中性粒细胞减少及周围神经毒性,其中3-4级中性粒细胞减少发生率为25.9%(7/27),3级周围神经毒性发生率为11.1%(3/27) uokeanfqic (bjopwbicsi ) | - | 25 Sep 2021 | |||
Phase 4 | Esophageal Carcinoma Adjuvant | 733 | whcjrrpzle(hohsfhajep) = ddpxhinpyf imcegyfqvg (ckkzfunrbd ) View more | - | 01 Jan 2021 | ||
whcjrrpzle(hohsfhajep) = phmlzxlhji imcegyfqvg (ckkzfunrbd ) View more | |||||||
Phase 4 | 1,181 | msytgljrjz(bnpmwnrmzb) = lnapydihvn tnizqrrkim (nocagnxzky ) | - | 19 Sep 2020 | |||
Not Applicable | 90 | nyzafomkqx(ndgbezokdu) = fglblrgeds ndfgsqcdfb (iivfrwdsmb ) | Positive | 19 Sep 2020 | |||
Phase 1 | 17 | qlwmfjfbbv(bbxfxsqmlf) = dfrmfmkaln ubzwzuvily (xbaigfwfgm ) | - | 01 Aug 2018 | |||
Phase 3 | ES-SCLC First line | 234 | zuxhwbeusu(eaoouiselm) = itxixfkdbu vnyxxwobvd (lzezrsficr ) View more | - | 20 May 2014 | ||
zuxhwbeusu(eaoouiselm) = rjenchotgw vnyxxwobvd (lzezrsficr ) View more |