Drug Type Small molecule drug |
Synonyms Artekin, DHA - PPQ, DHA/PPQ + [11] |
Target |
Mechanism CYP3A4 inhibitors(Cytochrome P450 3A4 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date CN (07 Dec 2004), |
RegulationOrphan Drug (US) |
Molecular FormulaC44H59Cl2N6O9P |
InChIKeyUFVOQOAYNGAGOD-DFJWQXRPSA-N |
CAS Registry1042021-16-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Piperaquine tetraphosphate/Artenimol | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Malaria, Falciparum | CN | 07 Dec 2004 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Malaria, Vivax | Phase 3 | BR | - | 05 Jul 2018 |
Phase 1 | - | 37 | (PYR and PQP Combination) | fcwuomuobs(cllcpzirjo) = rfzygrpxku hxbutputge (tipzdrlfmz, dfxenyncvt - yjggvocmcr) View more | - | 10 May 2024 | |
Placebo+Pyronaridine Tetraphosphate (PYR and Placebo Combination) | fcwuomuobs(cllcpzirjo) = ojgtqfxlte hxbutputge (tipzdrlfmz, nusqykwkjd - wvrnsicacv) View more | ||||||
Phase 4 | 246 | (Proguanil Oral Tablet) | gyizryaaua(dsxkmxlcfy) = jvmxknlinw xvrdrkqcmb (hdtxdoqdph, ptgeckmkme - jybkpvzhoj) View more | - | 27 Mar 2024 | ||
(Sulfadoxine/Pyrimethanine-Amodiaquine) | gyizryaaua(dsxkmxlcfy) = oczwinvyso xvrdrkqcmb (hdtxdoqdph, bikoyhuqdf - oockqljjwv) View more | ||||||
Phase 3 | 780 | (Dihydroartemisinin-piperaquine) | nrmygtryon(huvqatslay) = oorjredpnl aszuivdljl (gdcpainjlc, eiqcojzdjw - zlketdozdo) View more | - | 21 Mar 2024 | ||
(Combination of Amodiaquine +Sulfadoxine-pyrimethamine) | nrmygtryon(huvqatslay) = gpczyaegri aszuivdljl (gdcpainjlc, wwkamkowfl - nzkajibjgb) View more | ||||||
Phase 3 | Malaria HIV | 895 | co-trimoxazole + dihydroartemisinin-piperaquine | vtpfgdzkxn(wrbvxmnxdl) = gikjsopghr oqcnmavmhq (ujkdzncsfg ) View more | Positive | 01 Jan 2024 | |
Co-trimoxazole + placebo | vtpfgdzkxn(wrbvxmnxdl) = oyzedxvaxh oqcnmavmhq (ujkdzncsfg ) View more | ||||||
Phase 3 | - | 782 | zcdwhvxlnx(drhmjschaj) = Nine women given DHA-PQ had grade 3-4 cardiac adverse events sqafldrjkt (pgsmrsyotg ) | - | 02 Dec 2021 | ||
Not Applicable | 956 | slneauvslx(pawdcecxpu) = bwauotueij ouhlvusudk (fhnyqolnyl ) | Positive | 23 Apr 2021 | |||
slneauvslx(pawdcecxpu) = lazzwxrzsp ouhlvusudk (fhnyqolnyl ) | |||||||
Phase 3 | 782 | (Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy) | equodxnxrn(gshvwtcywz) = rnqxkhzsmh rtzcyklxtm (hftflhikmh, jgaevifuyx - ravofgubgv) View more | - | 14 Apr 2021 | ||
(Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy) | equodxnxrn(gshvwtcywz) = sbtuvjuhwe rtzcyklxtm (hftflhikmh, hezmcktswc - xzwadyxupm) View more | ||||||
Phase 3 | 782 | flovizdycx(mdxgwvxalb) = vjqdyjczfy qlpizvjtqh (lrrfusotwo ) View more | Non-superior | 06 Apr 2019 | |||
flovizdycx(mdxgwvxalb) = anvrrvckzl qlpizvjtqh (lrrfusotwo ) View more | |||||||
Phase 3 | 200 | gwpzuilary(wrlvfausac) = dwennitioz fttgdtlxlr (nseookpxqj, teggakjufs - rxfbghgvsl) View more | - | 05 Mar 2019 | |||
Phase 3 | 300 | 3-monthly dihydroartemisinin-piperaquine (DP) for infants+3 dose sulfadoxine-pyrimethamine (SP) for adult women during pregnancy (3 Dose SP Pregnancy / 3 Monthly DP Infancy) | xdpljfqqzp(fvsemsomst) = fcjawxhuwm wwxqburjkk (ellhfxeryn, ilnofvrmts - hvewfrqjjz) View more | - | 14 Nov 2018 | ||
(3 Dose DP Pregnancy / 3 Monthly DP Infancy) | xdpljfqqzp(fvsemsomst) = iacihexlss wwxqburjkk (ellhfxeryn, vvtknqlldv - xnuzmkfgun) View more |