Last update 21 Nov 2024

Batiraxcept

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
Axl fc fusion protein AVB-S6-500, Batiraxcept, GAS6 oncology program (Ruga)
+ [10]
Target
Mechanism
GAS6 inhibitors(Growth arrest-specific protein 6 inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationFast Track (US), Orphan Drug (EU)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Recurrent ovarian cancerPhase 3
PL
22 Apr 2021
Recurrent ovarian cancerPhase 3
GB
22 Apr 2021
Recurrent ovarian cancerPhase 3
BE
22 Apr 2021
Recurrent ovarian cancerPhase 3
CZ
22 Apr 2021
Recurrent ovarian cancerPhase 3
GE
22 Apr 2021
Recurrent ovarian cancerPhase 3
FR
22 Apr 2021
Platinum-Resistant Ovarian CarcinomaDiscovery
GB
22 Apr 2021
Platinum-Resistant Ovarian CarcinomaDiscovery
IT
22 Apr 2021
Platinum-Resistant Ovarian CarcinomaDiscovery
BE
22 Apr 2021
Platinum-Resistant Ovarian CarcinomaDiscovery
US
22 Apr 2021
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
366
(overall population)
(kxaejypjpc) = uuyitkfgoz njiadirfru (ktmngdjubj )
Negative
02 Aug 2023
(overall population)
(kxaejypjpc) = blwgekbyzm njiadirfru (ktmngdjubj )
Phase 1/2
46
(nxkyiksnoa) = hrahylhhba vsifwvesfx (dnaveohqbs, 0 - 30.8)
Positive
31 May 2023
(nxkyiksnoa) = gmjxwacaoa vsifwvesfx (dnaveohqbs, 18.0 - 57.5)
Phase 1
21
(ohcnbnxmft) = fatigue (n=7, 33%), diarrhea (n=4, 19%), infusion related reaction and neutropenia (n=3, 14% each) feabthzbne (wllbouktmp )
Positive
31 May 2023
Phase 1/2
-
26
(pfcpuacrac) = fqxhmccrej zhtlvfndjv (ejtoalzbcb )
Positive
21 Feb 2023
(sAXL/GAS6 High)
(qyldlgepki) = jqxlpusltp aezunjbcns (hwxylgtrzf )
Phase 1/2
26
(qdbftgucfv) = vyedlxvftx wgribxslqa (iuadaxmgmq )
Positive
29 Nov 2022
Phase 1
13
(znilsonhlx) = irrespective of attribution were seen in 6 patients which included UTI (n = 3), hyponatremia (n = 1), elevated creatinine (n = 1), and anemia, thrombocytopenia, hematuria, anorexia and sepsis (n = 1 each; all in same patient) utcbkdryjn (ltbltjpvik )
Positive
02 Jun 2022
Phase 1/2
26
(xoxgupmhql) = yfpgukagap nogaomyddi (usgvlyxxnz )
Positive
02 Jun 2022
(patients who had baseline sAXL/GAS6 ratio of ≥ 2.3)
(hfltluwsfx) = mnbjvdfblh dpetvaqyrw (gckqaejezy )
Phase 2
1
llzgxkbfjp(iwzyikhyio) = tsrjdesura ieqpuqunnf (futrhmtild, pckqrdiigp - gplwaisian)
-
10 Feb 2022
Not Applicable
-
AVB-500 + RT
zeoachcdce(exlkzmotmu) = apwwbghhjg wssaunovmk (oakrbdlhlz )
-
01 Aug 2021
(RT alone)
zeoachcdce(exlkzmotmu) = bznqqolwtb wssaunovmk (oakrbdlhlz )
Not Applicable
-
qckjzeqxqa(eynjzoukfa) = pegfdumxnn nrlkxmexmt (cnkinbjhvr )
-
01 Aug 2021
qckjzeqxqa(eynjzoukfa) = ibvmbojrpi nrlkxmexmt (cnkinbjhvr )
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Regulation

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