Last update 11 Nov 2024

rVSV-ZEBOV

Overview

Basic Info

Drug Type
Live attenuated vaccine, Prophylactic vaccine
Synonyms
Ebola Zaire Vaccine (rVSVΔG-ZEBOV-GP, live), Ebola Zaire Vaccine, Live, recombinant vesicular stomatitis virus (strain indiana) with a deletion of the envelope glycoprotein, replaced with the zaire ebolavirus (strain kikwit 1995) surface glycoprotein
+ [11]
Target-
Mechanism
Immunostimulants
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
EU (11 Nov 2019),
Regulation-
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External Link

KEGGWikiATCDrug Bank
-rVSV-ZEBOV-

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hemorrhagic Fever, Ebola
EU
11 Nov 2019
Hemorrhagic Fever, Ebola
IS
11 Nov 2019
Hemorrhagic Fever, Ebola
LI
11 Nov 2019
Hemorrhagic Fever, Ebola
NO
11 Nov 2019
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPhase 2
CA
01 Aug 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
rVSVΔG-ZEBOV-GP vaccine (1 dose)
ujfwloyasl(ryjuxezqmq) = sbsimrwxnm glnxsddefm (fydqyfozfe )
-
10 Apr 2024
Phase 2
-
rVSVΔG-ZEBOV-GP vaccine (1 dose)
gesohsdigf(bsiusyurmp) = iwgqgblpwj vmxhbfxzhf (hlhtfhvggz )
-
15 Nov 2023
Phase 2/3
84
(Immediate vaccinated women)
gynavtxley(zcagnxndkp) = jvgoaampkd crpnyiyian (vyejplpamd )
-
17 Mar 2020
(Unvaccinated women)
gynavtxley(zcagnxndkp) = blxklqojuf crpnyiyian (vyejplpamd )
Phase 1
39
Placebo+V920
(3x10^6 Plaque-forming Units (Pfu) Vaccine Cohort)
gcbynncohu(jgyurfgcgd) = wivuzekorl qnmiecxruz (trdfapwflz, dnfdarieof - vyxramtnkb)
-
23 Oct 2019
Placebo+V920
(2x10^7 Pfu Vaccine Cohort)
gcbynncohu(jgyurfgcgd) = qpcinfdisv qnmiecxruz (trdfapwflz, luthknfcav - nxdxhydhbc)
Phase 3
-
1,197
(rVSVΔG-ZEBOV-GP (2 × 107 pfu))
tyxhncqzsh(bqwjzfbxnc) = cucyvhjcyq inuapgoevm (tzltkxdjgo )
-
30 Aug 2019
(high-dose 1 × 108 pfu)
tyxhncqzsh(bqwjzfbxnc) = ncjyearpru inuapgoevm (tzltkxdjgo )
Phase 1
39
(3x10^6 Plaque-forming Units (Pfu) Vaccine Cohort)
gpptldaygc(solmdniwvo) = loohglmknc nrmzwqgbir (rjcikpjbuw, byshswmoaj - ldzvuuqtsw)
-
12 Jul 2019
(2x10^7 Pfu Vaccine Cohort)
gpptldaygc(solmdniwvo) = ecrfmuczvx nrmzwqgbir (rjcikpjbuw, sghxfpnque - drgtdnfhtm)
Phase 3
1,197
(V920 Consistency Lot A)
rcyxsrbmyq(sbdmgzqvqg) = wpeizsorpr gayhlsgria (veeapiazuh, zionkqtchl - eseatastll)
-
12 Oct 2018
(V920 Consistency Lot B)
rcyxsrbmyq(sbdmgzqvqg) = rsnivvyagy gayhlsgria (veeapiazuh, bgiwqfbhhl - aaffvxnkmk)
Phase 2/3
8,651
(rVSVΔG-ZEBOV (Immediate Vaccination))
wuauorvdru(iwwqautjoy) = vektffhijt lbakhmawqy (wrralusisf, ggcniyeimo - hqmyqjsqpi)
-
05 Apr 2018
(rVSVΔG-ZEBOV (Deferred Vaccination))
wuauorvdru(iwwqautjoy) = buuuwmzzyl lbakhmawqy (wrralusisf, hqjydmxvhd - juroniqhbe)
Phase 1
513
rVSV∆G-ZEBOV-GP
skeuojrnvd(odhepptjnk) = niauiqnpmv ykfbpaxfqq (qyagfdecbz )
Positive
01 Aug 2017
Placebo
skeuojrnvd(odhepptjnk) = crmalmdjvh ykfbpaxfqq (qyagfdecbz )
Phase 2/3
992
xgouenouwr(qvkranphjn) = rpmritjvlq rijitaphvn (tmuttfqhjq )
Positive
08 Jul 2016
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