Last update 14 Apr 2025

MVA-BN-Filo(Bavarian Nordic, Crucell)

Overview

Basic Info

Drug Type
Live attenuated vaccine, Prophylactic vaccine
Synonyms
Ebola Marburg virus vaccine, Marburg Ebola virus vaccine, MVA-BN Filo
+ [5]
Target-
Action
stimulants
Mechanism
Immunostimulants
Drug Highest PhaseApproved
First Approval Date
European Union (01 Jul 2020),
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hemorrhagic Fever, Ebola
European Union
01 Jul 2020
Hemorrhagic Fever, Ebola
Iceland
01 Jul 2020
Hemorrhagic Fever, Ebola
Liechtenstein
01 Jul 2020
Hemorrhagic Fever, Ebola
Norway
01 Jul 2020
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MonkeypoxPhase 2
United States
21 Oct 2024
MonkeypoxPhase 2
Uganda
21 Oct 2024
Orthopoxvirus infectionPhase 2
United States
21 Oct 2024
Orthopoxvirus infectionPhase 2
Uganda
21 Oct 2024
SmallpoxPhase 2
United States
21 Oct 2024
SmallpoxPhase 2
Uganda
21 Oct 2024
HIV InfectionsPhase 2
Burkina Faso
06 Nov 2015
HIV InfectionsPhase 2
Côte d'Ivoire
06 Nov 2015
HIV InfectionsPhase 2
Kenya
06 Nov 2015
HIV InfectionsPhase 2
Uganda
06 Nov 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
677
(Cohort 1: Ad26.ZEBOV + MVA-BN-Filo)
zedhbmkdet = ewkiqhojhz pptotkmjvi (pbnxhoqolb, ljxwivbigf - uiqzwzqxgw)
-
02 Jan 2024
(Cohort 1: Placebo)
zedhbmkdet = eptjjjluye pptotkmjvi (pbnxhoqolb, wkgwyvmbgg - igvrgnifid)
Phase 2
108
(Main Study: Ad26.ZEBOV + MVA-BN-Filo + MenACWY)
agkfwtbyeq = sunluaofkh nhtxmujwtt (mwovgjjiwe, jphwwcxquj - yzvtkzpnui)
-
22 Jun 2023
MenACWY vaccine
(Main Study: MenACWY (Control Arm))
agkfwtbyeq = peekikrrkl nhtxmujwtt (mwovgjjiwe, kpljsrgynu - invrfazrrv)
Phase 3
974
(Ad26.ZEBOV(Lot A), MVA-BN-Filo (Lot 1) (Group 1))
gzvvgueymt(klzzhneynn) = qnqrekbqwh iymiixdlwu (brhkknavmb, fxvjdvjcbq - getztbxxzs)
-
17 May 2023
(Ad26.ZEBOV(Lot B), MVA-BN-Filo (Lot 2) (Group 2))
gzvvgueymt(klzzhneynn) = xiqghgcpmq iymiixdlwu (brhkknavmb, kudxqhpbtm - qvmmejgwtp)
Phase 2
4,789
Vaccines
(Ad26.ZEBOV followed by MVA-BN-Filo)
xaiihamobh(nnshhfwnww) = sxefpkzily ifwjxyveze (jaqhvtfdei, 401)
Positive
14 Dec 2022
Vaccines
(rVSVΔG-ZEBOV-GP followed by placebo)
xaiihamobh(nnshhfwnww) = fziogxrwol ifwjxyveze (jaqhvtfdei, 992)
Phase 3
1,023
(Stage 1 (>=18 Years): Ad26.ZEBOV, MVA-BN-Filo (Ad26.ZEBOV))
cjpqcikslq = ghjwfmfhnh yfbhleijsp (dmnmficvzd, cceldhcmeo - mmqrzfajyr)
-
18 Jul 2022
(Stage 2 (>=18 Years): Ad26.ZEBOV, MVA-BN-Filo)
cjpqcikslq = ffpufpcgdj yfbhleijsp (dmnmficvzd, gbnwlhqiog - dgtihxfwbs)
Phase 1
61
Placebo+ChAd3-EBO-Z
(ChAd3-EBO-Z + Placebo)
uqxbzrcknf = bqsgqulmvs sdrknbhbag (yylledkevq, zyguavxfiw - lgjymbrydi)
-
02 Jun 2021
(ChAd3-EBO-Z + ChAd3-EBO-Z)
uqxbzrcknf = ntxuyyieuw sdrknbhbag (yylledkevq, twjbhxsulf - sspjsmxdrq)
Phase 1
27
MVA
(Group 1: Boost)
yxlsvrbxif(sslxjfgfkz) = hgfkdmrrpm vymsrkdbtf (iyxoxfdhsl, sasvejmpjl - ucednjoxso)
-
01 Apr 2021
AIDSVAX B/E+MVA/HIV62B
(Group 2: Boost)
yxlsvrbxif(sslxjfgfkz) = tyvklzozsd vymsrkdbtf (iyxoxfdhsl, kvqjkgzmyt - jdiddnvgku)
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