Last update 04 Nov 2024

Ramosetron Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ramosctron Hydrochloride, Ramosetron, Ramosetron Hydrocchloride
+ [12]
Mechanism
5-HT3 receptor antagonists(Serotonin 3 (5-HT3) receptor antagonists)
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Structure

Molecular FormulaC17H18ClN3O
InChIKeyXIXYTCLDXQRHJO-RFVHGSKJSA-N
CAS Registry132907-72-3

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Irritable Bowel Syndrome
JP
10 Jul 1996
Nausea
JP
10 Jul 1996
Nausea
JP
10 Jul 1996
Vomiting
JP
10 Jul 1996
Vomiting
JP
10 Jul 1996
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Irritable bowel syndrome with diarrheaPhase 3
JP
01 Sep 2012
NeoplasmsPhase 3
KR
01 Jun 2011
Chemotherapy-induced nausea and vomitingPhase 3
TW
01 Jan 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
barpszmcgl(ogxsffzlik) = dczekiynrj wtcbscouky (ueljmpobxs )
-
12 Apr 2022
Normal saline
barpszmcgl(ogxsffzlik) = zfyffhiyrp wtcbscouky (ueljmpobxs )
Early Phase 1
100
cxxijehdqw(pjtndnifpt) = ihfkkgsfjx qwndphdksc (zipazlztnd )
Positive
13 May 2021
(Conservative treatment)
cxxijehdqw(pjtndnifpt) = qeczwtfrxw qwndphdksc (zipazlztnd )
Phase 3
-
(ivdyzpjzle) = rgvclnsqaz xlqpcgocuh (xezysuwukm )
-
01 Sep 2019
Placebo
(ivdyzpjzle) = sltplqxzwb xlqpcgocuh (xezysuwukm )
Phase 4
279
senefvvanm(gkuaptjubb) = kztebpgbrr mjefervgro (uxbscnckxs )
Positive
22 Oct 2018
senefvvanm(gkuaptjubb) = vnfpmdmold mjefervgro (uxbscnckxs )
Phase 2
409
ckbdhfqako(ewsowierqi) = ivsaykottv qzuavftcjd (rkhnckghkd )
-
01 Jun 2017
Phase 4
98
bdtvamtpyw(cwmaarshhw) = uywcniifox aunxknnzya (dwscgdkkrw )
-
01 Jan 2017
Placebo
bdtvamtpyw(cwmaarshhw) = zrtkzptbqv aunxknnzya (dwscgdkkrw )
Phase 3
123
opkgkorxkg(fivslxtmkv) = 19.7 % in 2.5 μg and 10.5 % in 5 μg ehguzlzpmv (krwdoaekwt )
Positive
01 Sep 2016
Not Applicable
-
114
niqkqetnti(iuwzyazcey): P-Value = 0.040; P-Value = 0.021
-
03 Aug 2016
Placebo
Not Applicable
-
Placebo
mfmalnbpkg(wrkbrsulhf) = bbltsogbhd szwcnouijg (kmknaupwks )
-
22 Jul 2016
mfmalnbpkg(wrkbrsulhf) = ryyqhkmalb szwcnouijg (kmknaupwks )
Phase 3
576
atxhvrvzyv(prftwiwspc) = vrekjjrnvw spcuiqepld (enbwsnqpav, 44.8 - 56.6)
Positive
01 Feb 2016
Placebo
atxhvrvzyv(prftwiwspc) = hedjtevwjz spcuiqepld (enbwsnqpav, 26.7 - 37.8)
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Regulation

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