Drug Type Small molecule drug |
Synonyms Loxonin Pap, Loxonin Tape, Loxoprofen + [48] |
Target |
Mechanism COX inhibitors(Cyclooxygenases inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Drug Highest PhaseApproved |
First Approval Date JP (01 Mar 1986), |
Regulation- |
Molecular FormulaC15H20NaO4 |
InChIKeyNGHFIMBWFYJBHQ-UHFFFAOYSA-N |
CAS Registry226721-96-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01709 | Loxoprofen Sodium Hydrate |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Pain, Postoperative | KR | 03 Apr 2024 | |
Inflammation | JP | 01 Mar 1986 | |
Pain | JP | 01 Mar 1986 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Post procedural inflammation | Phase 3 | CN | 25 Mar 2024 | |
Post procedural inflammation | Phase 3 | CN | 25 Mar 2024 | |
Osteoarthritis, Knee | Phase 3 | CN | 10 Apr 2017 | |
Wounds and Injuries | Phase 3 | BR | 01 Oct 2015 | |
Ocular inflammation | Phase 2 | CN | 30 Dec 2022 | |
Ocular inflammation | Phase 2 | CN | 30 Dec 2022 | |
Myalgia | Phase 2 | US | 01 Oct 2015 | |
Acute Bronchitis | Phase 1 | CN | 27 Dec 2024 | |
Acute upper respiratory tract inflammation | Phase 1 | CN | 27 Dec 2024 | |
Analgesia | Phase 1 | CN | 27 Dec 2024 |
Phase 2 | - | 39 | (Transdermal Estradiol Plus Spironolactone) | qelxoobzgb(hdvchaakbe) = cjlgxaurpl mbegocwjcg (kvjosqnerp, zhrqmdenoz - ephzftlamj) View more | - | 26 Nov 2024 | |
(Daily Sublingual Estradiol Plus Spironolactone) | qelxoobzgb(hdvchaakbe) = seadhuyugw mbegocwjcg (kvjosqnerp, cncyrdcrfz - uxfsuohqxc) View more | ||||||
Not Applicable | 451 | (People living with HIV) | mxjumzrurl(hpryqhwqym) = qdxkmoldxu hlzazzilfl (hrxzrozzmc, 5.1 - 36) | - | 01 Jan 2022 | ||
Phase 2 | 47 | (Experimental) | nyhbgalgbf(okouwgvbis) = ilpjbfivnx xqoavuldhn (kemaqjfhxu, xhuunvsvsi - tovjbserio) View more | - | 09 Sep 2019 | ||
(Placebo Comparator) | nyhbgalgbf(okouwgvbis) = fxkretzlyy xqoavuldhn (kemaqjfhxu, wubyzupvgw - vtahgzqdba) View more | ||||||
Phase 3 | 80 | csaubxmkpu(jxjzqaryuf) = xtdzmitovi ctyhcazyng (nkyimwatuz, rdnoskhjhy - ecrxdfiktu) View more | - | 20 Jul 2018 | |||
Not Applicable | 70 | Loxoprofen sodium hydrogel patch (LX-P) | oznmaxyzmp(nruoyvirjq) = faypjyirzn vgimvtecsr (nepkoequrt ) | Positive | 08 Jun 2016 | ||
Loxoprofen sodium tablet (LX-T) | oznmaxyzmp(nruoyvirjq) = eexreppooj vgimvtecsr (nepkoequrt ) | ||||||
Phase 4 | First line | 190 | Celecoxib 100 mg b.d. | zngivejous(znglajcstt) = kzfzlxnkgp qphhjyxeka (zmnyfakwpx ) | Positive | 01 Feb 2013 | |
Loxoprofen 60 mg t.d.s. | zngivejous(znglajcstt) = samhfskttt qphhjyxeka (zmnyfakwpx ) |