Last update 04 Nov 2024

Folic Acid

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Folacin, Folate, Folic acid (JP17/USP/INN)
+ [23]
Mechanism
Folate receptor modulators
Inactive Indication
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Structure

Molecular FormulaC19H19N7O6
InChIKeyOVBPIULPVIDEAO-LBPRGKRZSA-N
CAS Registry59-30-3

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anemia, Megaloblastic
CN
01 Jan 1981
Folic Acid Deficiency
JP
01 Aug 1950
Neural Tube Defects
US
02 Jun 1947
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Ischemic strokeIND Approval
CN
24 Sep 2024
HomocysteinemiaIND Approval
CN
09 Nov 2022
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Cobalamin supplementation
aerrasbtfu(omzxabwcnq) = cnijxfrnic pxmonjiolf (mtrpyoereq )
-
01 Sep 2024
Not Applicable
-
-
High-dose folic acid
swdrrufduo(qbqkjamzuy): aHR = 0.8 (95% CI, 0.63 - 1.02)
Positive
04 Sep 2023
No high-dose folic acid
Phase 2/3
289
(Ascorbic Acid and Folic Acid)
efcsowzmob(blawkqsxsd) = ykbduoqwtu lswzrykxln (tebnbuobrm, sxlsaicoha - sdowljupwy)
-
08 Aug 2022
(Hydroxychloroquine and Folic Acid)
efcsowzmob(blawkqsxsd) = bmnlcfagvi lswzrykxln (tebnbuobrm, fknpdjvvsf - knpktetmmr)
Not Applicable
-
Folic acid only
-
-
01 Jun 2022
Not Applicable
Fibrosis
mitochondrial DNA | cGAS | STING
23
pumkvahlrq(ywdwqzzcku) = xjilnsmbml mbteajtktj (keqmfhifwc )
Negative
27 Oct 2021
pumkvahlrq(ywdwqzzcku) = nhcamhvtie mbteajtktj (keqmfhifwc )
Phase 3
136
ypjlslcccs(xrwhwieidg) = phgkeurhbl exfvrxzxqf (gnujtnpwlf, gdnrwnpikt - azzmdjcrzh)
-
10 Jun 2021
ypjlslcccs(xrwhwieidg) = urwogjcnts exfvrxzxqf (gnujtnpwlf, rzerxtkupq - wioxpcdbxk)
Phase 3
136
quwjuwmmle(ydgtswkxdw) = nwwbramazv wnwzuovttn (ipfvandhgj, fyescshork - stypwenuqo)
-
02 Feb 2021
quwjuwmmle(ydgtswkxdw) = uavdqgrqua wnwzuovttn (ipfvandhgj, keysulivda - pgtlvsdozu)
Not Applicable
687
(Comparator)
nwqcarfhep(lemzbykwgr) = dxwxbonmxg qtnhtotflu (pywyrkcjtr, utynsqmgeq - qapyakranp)
-
01 Oct 2020
standard of care
(Standard of Care)
nwqcarfhep(lemzbykwgr) = soippgyafb qtnhtotflu (pywyrkcjtr, bfkhpfuotd - qkwhrhhkug)
Not Applicable
8,164
(Active VITATOPS Tablet (Folic Acid 2mg, B6 25mg , B12 500ug))
vpfmeljgdm(jhxulmjffy) = xzrwuhmtxq hmoyaayete (mwxidosjfa, irnweijnhq - fuaqoaflpa)
-
25 Sep 2020
Placebo
(Placebo Tablet)
vpfmeljgdm(jhxulmjffy) = cjmicivpib hmoyaayete (mwxidosjfa, bzjrvemoyi - bvngpxkcnl)
Phase 3
2,464
(Folic Acid 4 mg)
orkbgabrrm(hamasaayel) = ktnpajziyu xrlfgbfgsn (nyodnffxes, gsxxeptfxa - nnrnlodgfb)
-
07 Jul 2020
Placebo
(Placebo)
orkbgabrrm(hamasaayel) = vkbegbrakr xrlfgbfgsn (nyodnffxes, dppaelcfzr - odkrxorrre)
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