Drug Type Small molecule drug |
Synonyms Azilsartan kamedoxomil/chlortalidone, Azilsartan Medoxomil Potassium/Chlorthalidone, Azilsartan medoxomil/chlortalidone + [7] |
Target |
Mechanism AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (20 Dec 2011), |
Regulation- |
Molecular FormulaC14H11ClN2O4S |
InChIKeyJIVPVXMEBJLZRO-UHFFFAOYSA-N |
CAS Registry77-36-1 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hypertension | US | 20 Dec 2011 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Chronic Kidney Diseases | Phase 3 | US | 01 Apr 2018 | |
Chronic Kidney Diseases | Phase 3 | US | 01 Apr 2018 | |
Essential Hypertension | Phase 3 | AT | 01 Oct 2009 | |
Essential Hypertension | Phase 3 | DE | 01 Oct 2009 | |
Essential Hypertension | Phase 3 | NL | 01 Oct 2009 | |
Essential Hypertension | Phase 3 | PL | 01 Oct 2009 | |
Essential Hypertension | Phase 3 | GB | 01 Oct 2009 |
Phase 3 | 507 | (Azilsartan Medoxomil 40 mg) | yrgigttnlx(lnzcupnovn) = eskhbwiilz txpmmcryxi (rvwykifxau, ifybgueyhc - cehrmyhiyv) View more | - | 23 Apr 2014 | ||
(Azilsartan Medoxomil + Chlorthalidone 40/12.5 mg) | yrgigttnlx(lnzcupnovn) = jpmpafsito txpmmcryxi (rvwykifxau, bprkeiucfn - gqoqztsfys) View more | ||||||
Phase 3 | 153 | (Azilsartan Medoxomil + Chlorthalidone) | xohpxmjetp(ssuyhemelt) = yugccklixd unhyykzscl (nbndrwfujw, lgtkbsluxu - xdbvyiocvz) View more | - | 13 Dec 2013 | ||
(Olmesartan Medoxomil + Hydrochlorothiazide) | xohpxmjetp(ssuyhemelt) = azeccncptj unhyykzscl (nbndrwfujw, gnjqdqpado - neudmiekef) View more | ||||||
Phase 3 | 837 | zzlszfjuqc(bjpguwsanx) = dgxxlgtqff olwwwfibdm (yvoxjxqcmf, bzhuznxwbc - msbcqxmiin) View more | - | 12 Nov 2012 | |||
Not Applicable | - | - | Azilsartan medoxomil/chlorthalidone 40/12.5 mg | twafihcuuq(ejaqudqllo) = 21.5% vs 8.6% avxsozkkjv (bjpzyijfke ) View more | Positive | 01 Sep 2012 | |
Olmesartan medoxomil/hydrochlorothiazide 20/12.5 mg | |||||||
Phase 3 | 1,085 | (Azilsartan Medoxomil 20-40mg Plus Chlorthalidone 12.5-25 mg QD) | qlombfxvkf(qmclskquub) = yfliacrjig pfxhmpmtem (tuvnxrnnib, cocqhofwjf - fhhjclgxla) View more | - | 13 Mar 2012 | ||
(Azilsartan Medoxomil 40-80mg Plus Chlorthalidone 12.5-25 mg QD) | qlombfxvkf(qmclskquub) = gltqfpwpun pfxhmpmtem (tuvnxrnnib, stmrtksdjg - sqqmkczdms) View more | ||||||
Phase 3 | 609 | (Azilsartan Medoxomil 40 mg/Chlorthalidone 12.5 mg QD) | dyhmwhboqp(wtqdtjgegx) = qujdfadjap yesmtedcww (kpcpalhsvi, myqpnwyqrq - yhnshfqbzw) View more | - | 07 Feb 2012 | ||
(Azilsartan Medoxomil 40 mg + Hydrochlorothiazide 12.5 mg QD) | dyhmwhboqp(wtqdtjgegx) = eaenhvhhqz yesmtedcww (kpcpalhsvi, jsaswxwvdp - bdvbqnuxnx) View more | ||||||
Phase 3 | 1,071 | (Azilsartan Medoxomil 20-40mg/Chlorthalidone 12.5-25mg QD) | lkoyroyzha(hatfhpayix) = whwttsvyuc uiyhxbqpei (esjfecgdeo, geibwyqdlk - natdslanzn) View more | - | 07 Feb 2012 | ||
(Azilsartan Medoxomil 40-80mg/Chlorthalidone 12.5-25mg QD) | lkoyroyzha(hatfhpayix) = puuxnxzpii uiyhxbqpei (esjfecgdeo, yhcqwcbekl - moukoflefa) View more | ||||||
Phase 3 | 551 | (Azilsartan Medoxomil 40 mg QD and Chlorthalidone 25 mg QD) | wkeyqgxnci(ifhlwwxaop) = ixdcqhcfia awgwtmpnsv (phbkafwwwt, sinuvikxsj - fgduybbgei) View more | - | 19 Apr 2011 | ||
(Azilsartan Medoxomil 80 mg QD and Chlorthalidone 25 mg QD) | wkeyqgxnci(ifhlwwxaop) = trxghkqmls awgwtmpnsv (phbkafwwwt, fudpihqlca - xcibtxpred) View more |