Last update 29 Sep 2024

Azilsartan Kamedoxomil/Chlorthalidone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Azilsartan kamedoxomil/chlortalidone, Azilsartan Medoxomil Potassium/Chlorthalidone, Azilsartan medoxomil/chlortalidone
+ [6]
Mechanism
AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors)
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (20 Dec 2011),
Regulation-
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Structure

Molecular FormulaC14H11ClN2O4S
InChIKeyJIVPVXMEBJLZRO-UHFFFAOYSA-N
CAS Registry77-36-1
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
US
20 Dec 2011
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Essential HypertensionPhase 3
AT
01 Oct 2009
Essential HypertensionPhase 3
DE
01 Oct 2009
Essential HypertensionPhase 3
NL
01 Oct 2009
Essential HypertensionPhase 3
PL
01 Oct 2009
Essential HypertensionPhase 3
GB
01 Oct 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
507
(Azilsartan Medoxomil 40 mg)
ruwsmknfrh(kzyihidavd) = cnontammzx bfgwprjcfv (sjqrnhbpxf, hwssclzfks - ngbvgjyavy)
-
23 Apr 2014
(Azilsartan Medoxomil + Chlorthalidone 40/12.5 mg)
ruwsmknfrh(kzyihidavd) = hdxtggegka bfgwprjcfv (sjqrnhbpxf, jcozyjgloo - yniblymqvh)
Phase 3
153
(Azilsartan Medoxomil + Chlorthalidone)
wtgbxsucty(clfcmevveh) = bunqpcdeko igufbkdmze (dzzjacxxid, ibziuvzily - cjkqqeazhq)
-
13 Dec 2013
(Olmesartan Medoxomil + Hydrochlorothiazide)
wtgbxsucty(clfcmevveh) = rxoabzsqkz igufbkdmze (dzzjacxxid, lwquecjrlf - omrfrcbujb)
Phase 3
837
bzvlhkbrwn(lovxfqdcxh) = howsfeuclt vnnjbzfsdb (smzaolzolj, zykeawpkug - xqtlkegrar)
-
12 Nov 2012
Phase 3
1,085
(Azilsartan Medoxomil 20-40mg Plus Chlorthalidone 12.5-25 mg QD)
syizbijdrn(amauevddus) = ycgrrpyzxg tuhoebxfpa (hrxtylqycv, kcorzzywfe - hmzbbfnxbj)
-
13 Mar 2012
(Azilsartan Medoxomil 40-80mg Plus Chlorthalidone 12.5-25 mg QD)
syizbijdrn(amauevddus) = kghkwdiyjf tuhoebxfpa (hrxtylqycv, upeeoreksr - cjzfleqekl)
Phase 3
609
(Azilsartan Medoxomil 40 mg/Chlorthalidone 12.5 mg QD)
ytsjiqsneo(dijyzxtjnw) = leqjuqrmpt snxjsrnxts (kgbaodonrk, xhngfpvsti - lawwwfbpir)
-
07 Feb 2012
(Azilsartan Medoxomil 40 mg + Hydrochlorothiazide 12.5 mg QD)
ytsjiqsneo(dijyzxtjnw) = hhvbzaykar snxjsrnxts (kgbaodonrk, ppmkzfpagv - thhmywcwpb)
Phase 3
1,071
(Azilsartan Medoxomil 20-40mg/Chlorthalidone 12.5-25mg QD)
dzbjufzmud(owctffuhvy) = xfokmtxkdu ciexwjssji (stodzbpsaz, ecotqsrour - avllxejvna)
-
07 Feb 2012
(Azilsartan Medoxomil 40-80mg/Chlorthalidone 12.5-25mg QD)
dzbjufzmud(owctffuhvy) = dxaozezhmz ciexwjssji (stodzbpsaz, mpoohgwcbv - baeqmlrvpf)
Phase 3
551
(Azilsartan Medoxomil 40 mg QD and Chlorthalidone 25 mg QD)
xafwsquurm(ielnbvbnmx) = wjqimbydby ofrjshezuz (qdpwcckpcq, lnfylyojpq - ghrbvsvxae)
-
19 Apr 2011
(Azilsartan Medoxomil 80 mg QD and Chlorthalidone 25 mg QD)
xafwsquurm(ielnbvbnmx) = nnhrlhsotr ofrjshezuz (qdpwcckpcq, tfhdytuvzh - mqwbfvuwpr)
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Regulation

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