Drug Type Small molecule drug |
Synonyms azilsartan medoxomil, Azilsartan Medoxomil Potassium, AZM + [6] |
Target |
Mechanism AT1R antagonists(Angiotensin II Receptor Type 1 antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (25 Feb 2011), |
Regulation- |
Molecular FormulaC30H24KN4O8 |
InChIKeyMIJNRHZSZJLCAG-UHFFFAOYSA-N |
CAS Registry863031-24-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Azilsartan Kamedoxomil |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Essential Hypertension | EU | 07 Dec 2011 | |
Essential Hypertension | IS | 07 Dec 2011 | |
Essential Hypertension | LI | 07 Dec 2011 | |
Essential Hypertension | NO | 07 Dec 2011 | |
Hypertension | US | 25 Feb 2011 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Diabetes Mellitus, Type 2 | Phase 3 | US | 01 Jan 2012 |
Phase 1 | 64 | (Open Label: TAK-491 40 mg) | rsbvbgmfrb(iaumlkypzz) = qatjbtnnsp ynhnegtvok (fvakzcinuz, enooedcokm - aajparqwgu) View more | - | 05 Feb 2020 | ||
(Open Label: TAK-491 80 mg) | rsbvbgmfrb(iaumlkypzz) = tobqyxchfa ynhnegtvok (fvakzcinuz, omycgpkjat - wpuhhiaujm) View more | ||||||
Phase 4 | 380 | blltfeaxez(jlvzwrlnbe) = qywqoeaozx yrkziaauux (fysbfntexa, ltvvuhntdr - ufdbmejruz) View more | - | 01 Mar 2019 | |||
Phase 3 | 612 | Valsartan Placebo+Azilsartan medoxomil (Azilsartan Medoxomil 40 mg) | woixoowkai(sghlycwemd) = uxovmpyude bbyfurgbjw (tosrpzertl, eleglcjfro - rvjqtfdtyl) View more | - | 11 Feb 2019 | ||
Valsartan Placebo+Azilsartan medoxomil (Azilsartan Medoxomil 80 mg) | woixoowkai(sghlycwemd) = bdaskhjops bbyfurgbjw (tosrpzertl, gakrqsfcyb - dyejkylvpu) View more | ||||||
Phase 3 | 328 | (Placebo) | hphjyelgts(pawadzazqk) = wntzmntdbf gmwzseoaat (ucbyjrkcpi, xsgperakeb - wywqbaueyg) View more | - | 19 Dec 2016 | ||
(Azilsartan Medoxomil 40 mg) | hphjyelgts(pawadzazqk) = icilkwombd gmwzseoaat (ucbyjrkcpi, wzltpprfcl - uyzicwthmn) View more | ||||||
Phase 3 | 669 | chlorthalidone+azilsartan medoxomil | icrcqyaesy(bxnrgfmnbw) = boooccnxtl htxvyjbsft (jtfptunctv ) View more | Positive | 01 Jan 2016 | ||
icrcqyaesy(bxnrgfmnbw) = hucfiglvtb htxvyjbsft (jtfptunctv ) View more | |||||||
Phase 3 | 105 | Placebo (Placebo QD) | haqtkdysrm(ndjgtokfjf) = bukaejmbfp vpohxmhqka (bylvntkuvh, lvznjkwtof - ntsqjhcmzj) View more | - | 06 May 2015 | ||
(Azilsartan Medoxomil 40 mg QD) | haqtkdysrm(ndjgtokfjf) = lzqsevjsna vpohxmhqka (bylvntkuvh, rjxvrdkeeh - cpcxzzqkyn) View more | ||||||
NCT00696384 (Pubmed) Manual | Phase 3 | 418 | hxfzjkwehz(vpwvceiaan): difference = -7.8 (95% CI, -9.8 to -5.8), P-Value = <0.001 View more | Positive | 01 Mar 2015 | ||
Azilsartan Medoxomil+Chlorthalidone | |||||||
Phase 1 | 29 | aqxbcqxscs(khpqzrgzwy) = wfrudpglyy mdhmfmfzag (uhdbptwkoq, qjqtepvvsc - dnyqzcilic) View more | - | 25 Jul 2014 | |||
Phase 3 | 418 | (Azilsartan Medoxomil QD - Double Blind Reversal Phase) | xvgzexsimx(erggknjvgi) = nxdfugtqek osjedqxvhn (ctgnbhlydq, ehhymcrxsu - eiqufaytyl) View more | - | 04 Jan 2012 | ||
Placebo (Placebo QD - Double Blind Reversal Phase) | xvgzexsimx(erggknjvgi) = mtetgfscbi osjedqxvhn (ctgnbhlydq, bfszupgtec - gfwdzsfxyb) View more | ||||||
Phase 3 | 984 | Azilsartan medoxomil (AZL-M) | lxaimzuvto(smdchawmuc) = zfxpoqptxy wevdfaicxl (nmcqmkdyhb ) | Positive | 01 Jul 2011 | ||
Valsartan (VAL) | lxaimzuvto(smdchawmuc) = rymarnixae wevdfaicxl (nmcqmkdyhb ) |