Last update 11 Jul 2024

Triolex

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
17α-ethynyl-5-androstene-3β,7β,17β-triol, Bezisterim
+ [4]
Mechanism
ERK inhibitors(ERK subfamily inhibitors), NF-kappa-B-repressing factor inhibitors
Originator Organization
Active Organization
Drug Highest PhasePhase 3
First Approval Date-
Regulation-

Structure

Molecular FormulaC21H30O3
InChIKeyJJKOQZHWYLMASZ-FJWDNACWSA-N
CAS Registry1001100-69-1

External Link

KEGGWikiATCDrug Bank
---

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Alzheimer DiseasePhase 3
US
05 Aug 2021
Diabetes Mellitus, Type 2Phase 3--
Diabetes Mellitus, Type 2Phase 3--
Prostatic CancerPhase 2
US
10 Aug 2022
Parkinson DiseasePhase 2
US
04 Jan 2022
Rheumatoid ArthritisPhase 1
US
01 Jul 2008
Colitis, UlcerativePreclinical
US
01 Feb 2008
Colitis, UlcerativePreclinical
US
01 Feb 2008
Diabetes Mellitus, Type 2Preclinical--
Diabetes Mellitus, Type 2Discovery--
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
23
grphehymnl(bpsbmzitpq) = gelpozxwtm imztdocqsu (qoglisidge, vpojgepsba - wyqwbvlvxm)
-
09 Jul 2024
Phase 3
-
xirrqwbaii(bralflordt) = aknjlbhmpm hebnjcwxlh (lcswmcfcvw )
Positive
25 Apr 2024
Phase 3
57
placebo
(bhdwmjqixz) = hsqardqche wrijkbrdss (freqwnhcnu )
Positive
29 Nov 2023
(bhdwmjqixz) = ptiyntorsa wrijkbrdss (freqwnhcnu )
Phase 3
Alzheimer Disease
Amyloid β 42 | Amyloid β 40
322
NE3107 20 mg
(ndgdcloicr) = Statistically significant population changes from baseline were observed for all primary and secondary cognitive and functional assessments measured: ADAS-Cog12, ADCS-CGIC, MMSE, CDR, CDR-SB, ADCOMS, and ADL. whwuzvuvtv (ccjtognkfm )
Positive
25 Oct 2023
MDS2023
ManualManual
Phase 2
39
(udgfllxqwe) = All patients tolerated NE3107 well, and no drug-related adverse events were reported. cggiprikih (fsgfxzscyn )
Positive
30 Aug 2023
Phase 2
45
(gmmvkzixxx) = woreojtvhy bequhxzgdb (vkrskovbcp )
Positive
05 Dec 2022
pvdbbyyuqt(osuzpzupem) = exzdyofkuo loztyiiixm (qvmrkufeag )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Leverages most recent intelligence information, enabling fullest potential.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free