Last update 31 May 2025

Darusentan

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
HMR 4005, HMR-4005, LU-135252
Target
Action
antagonists
Mechanism
ETA antagonists(Endothelin receptor type A antagonists)
Therapeutic Areas
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC22H22N2O6
InChIKeyFEJVSJIALLTFRP-LJQANCHMSA-N
CAS Registry171714-84-4

External Link

KEGGWikiATCDrug Bank
-Darusentan-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Resistant hypertensionPhase 3
United States
01 Jun 2006
Resistant hypertensionPhase 3
Argentina
01 Jun 2006
Resistant hypertensionPhase 3
Brazil
01 Jun 2006
Resistant hypertensionPhase 3
Canada
01 Jun 2006
Resistant hypertensionPhase 3
Denmark
01 Jun 2006
Resistant hypertensionPhase 3
France
01 Jun 2006
Resistant hypertensionPhase 3
Germany
01 Jun 2006
Resistant hypertensionPhase 3
Italy
01 Jun 2006
Resistant hypertensionPhase 3
Spain
01 Jun 2006
Resistant hypertensionPhase 3
Sweden
01 Jun 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
40
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-
15 Aug 2014
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Phase 3
849
nfsalljvwp(pzausuhpoi) = qvktgltruc bqclkypqal (ciwntmcjiw )
-
01 Nov 2010
Placebo
nfsalljvwp(pzausuhpoi) = fibgmuulrz bqclkypqal (ciwntmcjiw )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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