Last update 01 Nov 2024

Anti-p53 T-cell receptor-transduced PBL(NCI)

Overview

Basic Info

Drug Type
T-lymphocyte cell therapy
Synonyms-
Target-
Mechanism
Cell replacements
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal DiseasesUrogenital Diseases
Active Indication-
Inactive Indication
Kidney NeoplasmsMelanoma, Cutaneous MalignantNeoplasm Metastasis
Originator Organization
National Cancer InstituteNational Cancer Institute
Active Organization-
Inactive Organization
National Institutes of Health Clinical Center
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with Anti-p53 T-cell receptor-transduced PBL(NCI)
NCT00704938 / TerminatedPhase 2IIT
Phase II Study of Metastatic Cancer That Overexpresses p53 Using Lymphodepleting Conditioning Followed by Infusion of Anti-P53 TCR-Gene Engineered Lymphocytes and Dendritic Cell Vaccination
100 Clinical Results associated with Anti-p53 T-cell receptor-transduced PBL(NCI)
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100 Translational Medicine associated with Anti-p53 T-cell receptor-transduced PBL(NCI)
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100 Patents (Medical) associated with Anti-p53 T-cell receptor-transduced PBL(NCI)
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100 Deals associated with Anti-p53 T-cell receptor-transduced PBL(NCI)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Kidney NeoplasmsPhase 2
US
National Institutes of Health Clinical Center
01 Jun 2008
Melanoma, Cutaneous MalignantPhase 2
US
National Institutes of Health Clinical Center
01 Jun 2008
Neoplasm MetastasisPhase 2
US
National Institutes of Health Clinical Center
01 Jun 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT00704938 (CTgov)
Phase 2
Melanoma, Cutaneous Malignant | Neoplasm Metastasis | Kidney Neoplasms
3
(Anti-p53 TCR PBL + DC + IL-2: Melanoma/RCC)
ffrsxswjcs(ezwelmnwjp) = hieatyhuqs hxbkpejypa (dahdahhfbo, dqgxvocqyq - enlnoqaghy)
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-
14 Aug 2012
(Anti-p53 TCR PBL + DC + IL-2: Other Histology)
ffrsxswjcs(ezwelmnwjp) = hocrkjixkj hxbkpejypa (dahdahhfbo, rjavleiqye - tcqkxprtrc)
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Clinical Trial

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Approval

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Regulation

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