Last update 27 Sep 2025

Hymecromone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
4-methylumbelliferone, Htmecromone, Hymecreomone
+ [14]
Action
modulators
Mechanism
Hyaluronic acid modulators
Inactive Indication
Originator Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
(13 May 2025),
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC10H8O3
InChIKeyHSHNITRMYYLLCV-UHFFFAOYSA-N
CAS Registry90-33-5

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Biliary Tract Diseases--13 May 2025
Cholestasis---
Spasm---
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Idiopathic Pulmonary FibrosisPhase 2
United States
05 May 2025
Cholangitis, SclerosingPhase 2
United States
10 May 2023
Cholangitis, SclerosingPhase 2
United States
10 May 2023
Hypertension, PulmonaryPhase 2
United States
-
Respiratory DiseasesPhase 1
United States
01 Dec 2020
Myocardial IschemiaPreclinical
Iran
06 Jan 2024
Reperfusion InjuryPreclinical
Iran
06 Jan 2024
Hepatocellular CarcinomaPreclinical
Italy
20 Apr 2023
Brain DiseasesPreclinical
France
16 Nov 2022
Multiple SclerosisDiscovery
United States
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
16
nowaubhmbs(sytfwvkeqs) = widymonbwi kpzfzigrcz (nsonehcqbx, -1.5 to 2.7)
Positive
15 Aug 2025
Phase 2
17
(Experimental Treatment Oral Hymecromone (H01))
ihovajkejk(rhsjgbnoec) = croivjwwdi tgpvupkouw (ahnnkezmgr, 2.65)
-
26 Nov 2024
Placebo
(Placebo)
ihovajkejk(rhsjgbnoec) = jnfdcegkqv tgpvupkouw (ahnnkezmgr, 4.16)
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Core Patent

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Clinical Trial

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Approval

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Regulation

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