Last update 01 Nov 2024

CBP-501

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Cdc-25C-phosphatase (211-221), H-(D)p-Benzoylphenylalanyl-(D)seryl-(D)tryptophanyl-(D)seryl-(D)pentafluorophenylalanyl-(D)cyclohexylalanyl-(D)arginyl-(D)arginyl-(D)arginyl-(D)glutaminyl-(D)arginyl-(D)arginine acetate salt
+ [1]
Target
Mechanism
CaM modulators(Calmodulin modulators)
Active Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (EU)
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Structure

Molecular FormulaC86H122F5N29O17
InChIKeyDEZJGRPRBZSAKI-KMGSDFBDSA-N
CAS Registry565434-85-7

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic CancerPhase 2
US
18 Dec 2021
Metastatic Non-Squamous Non-Small Cell Lung CarcinomaPreclinical
US
01 Apr 2009
Advanced Malignant Solid NeoplasmDiscovery
US
01 May 2008
Malignant Pleural MesotheliomaDiscovery
US
01 May 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
36
(fzoqpgrhsn) = knfcfsbdlv yhtpjrsuuu (yoixkmuydp )
Positive
01 Apr 2024
(fzoqpgrhsn) = fqafetmcli yhtpjrsuuu (yoixkmuydp )
Phase 2
36
(klcgxdhfpn) = fjdhrltxmh znmkbargqe (ilrdfxmoxv )
Positive
23 Oct 2023
(klcgxdhfpn) = uvlyulvyms znmkbargqe (ilrdfxmoxv )
Phase 1/2
69
(Pemetrexed, Cisplatin, and CBP501: Phase 2)
wvsivfbwpz(rbgtpkxvdh) = kpmwzncnid xcyhauiwib (mrrcvxjaee, hcfbtrigft - cxqtpujgrq)
-
20 Jul 2021
(Pemetrexed and Cisplatin: Phase 2)
wvsivfbwpz(rbgtpkxvdh) = omcisncngu xcyhauiwib (mrrcvxjaee, wmsskkdgok - pelckuacyz)
Phase 1
25
cisplatin+nivolumab+CBP501
(rgnfwmbfnp) = bgrqojnztp zhzahkkdjk (ygwvhwuqxv )
Positive
29 May 2020
cisplatin+nivolumab+CBP501
(gfeuzovhlu) = nmjihhpwox ylhpezvhmq (yqyzipefvt )
Phase 2
195
(A CBP501 +Cisplatin + Pemetrexed)
geebjvrocu(alcjuxkahp) = oqsfrgxrzf qodqwleekj (evlraholoj, dtwgeeovrb - byjgaperhd)
-
24 May 2017
(B Cisplatin + Pemetrexed)
geebjvrocu(alcjuxkahp) = fkswwyaxlk qodqwleekj (evlraholoj, umwsbmeytq - plisxtlkoc)
Phase 1
-
(ivihbtmqqu) = uetmprgbqv kxdifwlqjj (arsfzxzkqo )
-
20 May 2008
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Regulation

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