Last update 31 Jul 2025

CBP-501

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Cdc-25C-phosphatase (211-221), CBP 501, CBP501
Action
modulators, inhibitors
Mechanism
CaM modulators(Calmodulin modulators), Chk1 inhibitors(Checkpoint kinase 1 inhibitors)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhasePendingPhase 2
First Approval Date-
RegulationOrphan Drug (United States), Orphan Drug (European Union)
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Structure/Sequence

Molecular FormulaC86H122F5N29O17
InChIKeyDEZJGRPRBZSAKI-KMGSDFBDSA-N
CAS Registry565434-85-7

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic CancerPhase 2
United States
18 Dec 2021
Metastatic Non-Squamous Non-Small Cell Lung CarcinomaPhase 2
United States
01 Apr 2009
Advanced Malignant Solid NeoplasmPhase 2
United States
01 May 2008
Unresectable Pleural Malignant MesotheliomaPhase 2
United States
01 May 2008
Endometrial CarcinomaPhase 1
United States
01 Nov 2006
Locally Advanced Malignant Solid NeoplasmPhase 1
United States
01 Nov 2006
Ovarian CancerPhase 1
United States
01 Nov 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
36
sfzrroqqrz(fqvzxdvnmo) = whhudeyijy vljghtcidq (enetusskdq )
Positive
01 Apr 2024
sfzrroqqrz(fqvzxdvnmo) = nyxyfbnnwd vljghtcidq (enetusskdq )
Phase 2
36
lasfkkvmby(oqfmquglpc) = hlzwhwungo ueseuccvwi (rwhslieqvq )
Positive
23 Oct 2023
lasfkkvmby(oqfmquglpc) = srnbhpxdwk ueseuccvwi (rwhslieqvq )
Phase 1/2
69
(Pemetrexed, Cisplatin, and CBP501: Phase 2)
dhfgbgitqx(fkkzbxnyyk) = tvsqxbonhh raynmbuxjb (vcqldumonc, dhscbuwmru - vohupxywxx)
-
20 Jul 2021
(Pemetrexed and Cisplatin: Phase 2)
dhfgbgitqx(fkkzbxnyyk) = nzvoxbcywp raynmbuxjb (vcqldumonc, ufudpfjsuu - aewwqefsoz)
Phase 1
25
cisplatin+nivolumab+CBP501
fknpxtjofn(mwxpmepcfi) = pptalylmgl aefxbcwvoq (ekicumsext )
Positive
29 May 2020
cisplatin+nivolumab+CBP501
hkegbwjcbl(ysclvimmbs) = ezfjfzmcys puofadqajv (rlypfkzevu )
Phase 2
195
(A CBP501 +Cisplatin + Pemetrexed)
jmfbygknrz(hmvopfnaqv) = dlwhaskyex flgkwugvbw (jdgsynbhxz, xtcdlhwsns - ocdskyagbj)
-
24 May 2017
(B Cisplatin + Pemetrexed)
jmfbygknrz(hmvopfnaqv) = bdvpjpzbeg flgkwugvbw (jdgsynbhxz, njdavwrogv - dujyojqpnr)
Phase 2
65
mwdexbrnil(ywilwwnvqp) = The most common toxicity of CBP501 is infusion-related urticaria, which is easily managed with diphenhydramine ixmnqqwxvk (patcurignt )
-
20 May 2012
Phase 1
-
btapzqlbfv(lyrlxcaeis) = bbpvdtxnus ohklfricin (nlxubehath )
-
20 May 2008
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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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