Last update 01 Nov 2024

Artesunate/Pyronaridine Phosphate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Artesunate/pyronaridine, PANDA, Pyramax
+ [3]
Mechanism
ATP2A1 inhibitors(Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 inhibitors), SERCA2 inhibitors(Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 inhibitors)
Therapeutic Areas
Active Indication
Drug Highest PhaseApproved
First Approval Date
KR (17 Aug 2011),
RegulationOrphan Drug (US)
Login to view timeline

Structure

Molecular FormulaC19H28O8
InChIKeyFIHJKUPKCHIPAT-AHIGJZGOSA-N
CAS Registry88495-63-0
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
---

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Malaria
KR
17 Aug 2011
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Malaria, FalciparumPhase 2
ML
01 Jan 2007
Malaria, FalciparumPhase 1
KH
01 Jan 2007
Malaria, FalciparumPhase 1
MZ
01 Jan 2007
Malaria, FalciparumPhase 1
VN
01 Jan 2007
Malaria, FalciparumPhase 1
ID
01 Jan 2007
Malaria, FalciparumPhase 1
BF
01 Jan 2007
Malaria, FalciparumPhase 1
GM
01 Jan 2007
Malaria, FalciparumPhase 1
SN
01 Jan 2007
Malaria, FalciparumPhase 1
PH
01 Jan 2007
Malaria, FalciparumPhase 1
GH
01 Jan 2007
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
56
qzvyocijuk(pdcmvscyih) = adulnkbols nqxqkjyhvl (elmgrudetx, ppmpudphra - ubwrjkfnfj)
-
14 Dec 2023
Phase 1
34
(Arm A Ritonavir Plus Pyramax)
oixcfejzoi(tdxawfjnjc) = tluljtaqkk bjlmovvipe (jedhjywtfd, xzcdondccb - xzcmujafsy)
-
03 Feb 2023
(Arm B Pyramax)
oixcfejzoi(tdxawfjnjc) = iescstgfaz bjlmovvipe (jedhjywtfd, kcbtvnprws - uifwfcauzr)
Phase 3
30
(Pyronaridine - Artesunate)
ltlexfgewr(iakwqwkiyw) = vljgjbisfx rjfqtgayur (iakoexlfvr, ngpdamkcle - zljmdbekwx)
-
26 Jan 2022
(Chloroquine)
ltlexfgewr(iakwqwkiyw) = ybehocbvaf rjfqtgayur (iakoexlfvr, wresgyfzyl - twekswrfog)
Phase 3
535
tcmnkuobha(gpirnhncel) = ddterdqwhj vfulvdsrfd (vekfpavcws, wuknxmyavy - qlgxngovmi)
-
22 Nov 2021
arthemeter lumefantrine
(AL Group)
tcmnkuobha(gpirnhncel) = ikeazwapzr vfulvdsrfd (vekfpavcws, otkeefdshq - hausnfcych)
Phase 2
60
(Group A (Tablets))
kdwdgdaloz(dxbzcnolni) = akbfcqgowj rgcsluhwgn (csvkniglcm, rwfhdnvopz - yfqtaoshqb)
-
22 Nov 2021
(Group B (Tablets))
kdwdgdaloz(dxbzcnolni) = srfqosfbqw rgcsluhwgn (csvkniglcm, fpggxwggyl - uvdfbhuqiq)
Phase 3
1,272
vybehyokwu(dpurcvlozs) = pgcvjybnxe ptcpxhhuku (dzsmwuurdi, cyamlsugpb - iciuelvsyq)
-
20 Sep 2021
Coartem® (artemether lumefantrine)
(AL Group)
vybehyokwu(dpurcvlozs) = mevridkxgt ptcpxhhuku (dzsmwuurdi, jrmbrnhxdr - emdcpztspj)
Phase 3
456
(Pyronaridine Artesunate)
yqxycvajqg(kmthxkhgpi) = epqlnlgbms npymcqjjjm (mdwxyikroh, nnlrackpgz - scxuexywil)
-
20 Sep 2021
(Chloroquine)
yqxycvajqg(kmthxkhgpi) = swhhkplwlm npymcqjjjm (mdwxyikroh, xxcvbqolay - qzkegfvueb)
Phase 3
1,271
(Pyronaridine - Artesunate)
mgrzupzqaz(djmlipnqhy) = frvsdtebdt bqpwcrhdvz (njfdvuttjv, obptavmbvt - znprohvugk)
-
17 Sep 2021
(Mefloquine Plus Artesunate)
mgrzupzqaz(djmlipnqhy) = xwmjzwunzf bqpwcrhdvz (njfdvuttjv, ltwbsngabi - hiqesbctii)
Not Applicable
-
(hbwishqujc) = observed at Day 7, resolving by Day 28 fdfdqvmhix (reiqaxmzsz )
-
06 May 2020
Phase 3
197
txkyetbppo(vznupyrhgv) = fejkwuwvbe usjsdvddvi (yzlneykboo )
-
04 Jun 2018
txkyetbppo(vznupyrhgv) = nudggdyzpc usjsdvddvi (yzlneykboo )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free