Drug Type Small molecule drug |
Synonyms Artesunate/pyronaridine, PANDA, Pyramax + [3] |
Target |
Mechanism ATP2A1 inhibitors(Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 inhibitors), SERCA2 inhibitors(Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date KR (17 Aug 2011), |
RegulationOrphan Drug (US) |
Molecular FormulaC19H28O8 |
InChIKeyFIHJKUPKCHIPAT-AHIGJZGOSA-N |
CAS Registry88495-63-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Malaria | KR | 17 Aug 2011 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Malaria, Falciparum | Phase 2 | ML | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | KH | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | MZ | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | VN | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | ID | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | BF | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | GM | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | SN | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | PH | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | GH | 01 Jan 2007 |
Phase 1 | 56 | qzvyocijuk(pdcmvscyih) = adulnkbols nqxqkjyhvl (elmgrudetx, ppmpudphra - ubwrjkfnfj) View more | - | 14 Dec 2023 | |||
Phase 1 | 34 | oixcfejzoi(tdxawfjnjc) = tluljtaqkk bjlmovvipe (jedhjywtfd, xzcdondccb - xzcmujafsy) View more | - | 03 Feb 2023 | |||
(Arm B Pyramax) | oixcfejzoi(tdxawfjnjc) = iescstgfaz bjlmovvipe (jedhjywtfd, kcbtvnprws - uifwfcauzr) View more | ||||||
Phase 3 | 30 | (Pyronaridine - Artesunate) | ltlexfgewr(iakwqwkiyw) = vljgjbisfx rjfqtgayur (iakoexlfvr, ngpdamkcle - zljmdbekwx) View more | - | 26 Jan 2022 | ||
(Chloroquine) | ltlexfgewr(iakwqwkiyw) = ybehocbvaf rjfqtgayur (iakoexlfvr, wresgyfzyl - twekswrfog) View more | ||||||
Phase 3 | 535 | (PA Group) | tcmnkuobha(gpirnhncel) = ddterdqwhj vfulvdsrfd (vekfpavcws, wuknxmyavy - qlgxngovmi) View more | - | 22 Nov 2021 | ||
arthemeter lumefantrine (AL Group) | tcmnkuobha(gpirnhncel) = ikeazwapzr vfulvdsrfd (vekfpavcws, otkeefdshq - hausnfcych) View more | ||||||
Phase 2 | 60 | (Group A (Tablets)) | kdwdgdaloz(dxbzcnolni) = akbfcqgowj rgcsluhwgn (csvkniglcm, rwfhdnvopz - yfqtaoshqb) View more | - | 22 Nov 2021 | ||
(Group B (Tablets)) | kdwdgdaloz(dxbzcnolni) = srfqosfbqw rgcsluhwgn (csvkniglcm, fpggxwggyl - uvdfbhuqiq) View more | ||||||
Phase 3 | 1,272 | (PA Group) | vybehyokwu(dpurcvlozs) = pgcvjybnxe ptcpxhhuku (dzsmwuurdi, cyamlsugpb - iciuelvsyq) View more | - | 20 Sep 2021 | ||
Coartem® (artemether lumefantrine) (AL Group) | vybehyokwu(dpurcvlozs) = mevridkxgt ptcpxhhuku (dzsmwuurdi, jrmbrnhxdr - emdcpztspj) View more | ||||||
Phase 3 | 456 | (Pyronaridine Artesunate) | yqxycvajqg(kmthxkhgpi) = epqlnlgbms npymcqjjjm (mdwxyikroh, nnlrackpgz - scxuexywil) View more | - | 20 Sep 2021 | ||
(Chloroquine) | yqxycvajqg(kmthxkhgpi) = swhhkplwlm npymcqjjjm (mdwxyikroh, xxcvbqolay - qzkegfvueb) View more | ||||||
Phase 3 | 1,271 | (Pyronaridine - Artesunate) | mgrzupzqaz(djmlipnqhy) = frvsdtebdt bqpwcrhdvz (njfdvuttjv, obptavmbvt - znprohvugk) View more | - | 17 Sep 2021 | ||
(Mefloquine Plus Artesunate) | mgrzupzqaz(djmlipnqhy) = xwmjzwunzf bqpwcrhdvz (njfdvuttjv, ltwbsngabi - hiqesbctii) View more | ||||||
Not Applicable | - | (hbwishqujc) = observed at Day 7, resolving by Day 28 fdfdqvmhix (reiqaxmzsz ) View more | - | 06 May 2020 | |||
Phase 3 | 197 | txkyetbppo(vznupyrhgv) = fejkwuwvbe usjsdvddvi (yzlneykboo ) View more | - | 04 Jun 2018 | |||
txkyetbppo(vznupyrhgv) = nudggdyzpc usjsdvddvi (yzlneykboo ) View more |