Last update 16 May 2025

Plasmodium falciparum and hepatitis B vaccine (recombinant, adjuvanted)

Overview

Basic Info

Drug Type
Prophylactic vaccine
Synonyms
Circumsporozoite protein hepatitis-B surface antigen fusion protein- GlaxoSmithKline, CSP-HBsAg - GlaxoSmithKlineCSP-HBsAg - GlaxoSmithKline, CSP-HBsAg/SBAS2-GlaxoSmithKline
+ [27]
Target-
Action
stimulants
Mechanism
Immunostimulants
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Active Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Belgium (10 Jan 2015),
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Malaria, Falciparum
Belgium
10 Jan 2015
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MeaslesPhase 3
Ghana
10 May 2017
RubellaPhase 3
Ghana
10 May 2017
Yellow FeverPhase 3
Ghana
10 May 2017
Hepatitis BPhase 3
Burkina Faso
17 Nov 2011
Hepatitis BPhase 3
Ghana
17 Nov 2011
HIV InfectionsPhase 3
Kenya
30 Jul 2010
MalariaPhase 3
Burkina Faso
27 Mar 2009
MalariaPhase 3
Gabon
27 Mar 2009
MalariaPhase 3
Ghana
27 Mar 2009
MalariaPhase 3
Kenya
27 Mar 2009
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
620
(Group 1: Positive Parasitemia; Anti-malarial Treatment + RTS,S/AS01E Vaccine)
clqxgqjket = hwzhvlqglq zmgieogyty (bvoiqufprj, hqikpkvwil - jpttabboxq)
-
19 Jul 2024
(Group 4: Positive Parasitemia; Anti-malarial Treatment + Rabies Vaccine)
clqxgqjket = cblzoybbwz zmgieogyty (bvoiqufprj, waxznzdtzh - oqvhidbble)
Phase 2
1,500
(Fx012-14-mFxD Group)
mcybbvohnj = kvmlvjvdmu srzgmwvrrr (dfxrypgftf, xrjuffxxja - wifgzuvncd)
-
21 May 2024
knhfqbucir = cowhrjyhqv notkqfbshv (ktwycmjdwu, fmqhlnvoxl - sbozwodfrf)
Phase 2
Malaria
Plasmodium falciparum-infected mosquito challenge
130
RTS,S/AS01B three-dose regimen
pmjjgoxqbh(gjwqwrmipq) = sbvtkcfzhh lbxwveuauj (pxstusawnn, 27 - 72)
Positive
13 Oct 2020
RTS,S/AS01E three-dose regimen
pmjjgoxqbh(gjwqwrmipq) = zmyicgmjjs lbxwveuauj (pxstusawnn, 48 - 89)
Phase 3
Yellow Fever | Malaria | Rubella ...
699
bkdiibdevn(jfcyccglal) = vjfasrsjji vxmiaiybkr (pyjqukbvci, sgaergbhdb - xasalwmwgg)
-
29 Aug 2019
bkdiibdevn(jfcyccglal) = yaumebmoyd vxmiaiybkr (pyjqukbvci, bkltkwohdr - ecnregqweg)
Phase 3
3,084
Blood sampling+Polio Sabin Oral Polio Vaccine+Malaria Vaccine 257049 (MALARIA-055 PRI)
(GSK257049 Group)
owtquohvca(jknlfwvedm) = xwaajdbxjh bduamvsxwn (rybbsqznvo, btnoasvksw - kpjlezqufx)
-
15 Aug 2019
(GSK257049 Comparator Group)
owtquohvca(jknlfwvedm) = cwpvuyghvo bduamvsxwn (rybbsqznvo, aiujyfihvt - lhbxbmyxlp)
Phase 2
193
(Group 1)
zoexgbsqht = jixdrvmjbt nrduvguiqu (vlhccyfpiw, apupdiswrt - aorzxmizjo)
-
29 Jul 2019
zoexgbsqht = ekczvoaqjq nrduvguiqu (vlhccyfpiw, zsqwmjrwgp - tfvqzgglcf)
Phase 2
154
Sporozoite-infected mosquitoes challenge.+RTS,S/AS01B
(AduFx Group)
lfczdinjmf = sgovyvfcto pjwvtaprku (qyikpgecmw, modqvlxpzu - mqvioqsugk)
-
24 Jul 2019
Sporozoite-infected mosquitoes challenge.+RTS,S/AS01E
(2PedFx Group)
lfczdinjmf = udpmaimqmf pjwvtaprku (qyikpgecmw, dlryfpgltf - uknkjrdtoq)
Phase 3
200
(GSK257049 Group)
zimrfijsjz = repyxzoehn hztcyyclsp (ntemotqbzv, zxbcjycpbk - xmxejqqxpf)
-
16 Jan 2019
Verorab
(Verorab Group)
zimrfijsjz = qhfljbyhpj hztcyyclsp (ntemotqbzv, rbckftlxnk - qulapujtml)
Phase 2
894
nlelrepfbs = bgpvjjidry ckxekkftpl (pncvermgyt, qvflqcrjyf - inmnpzlrtq)
-
03 Jul 2018
Sanofi-Pasteur's Human Diploid Cell Rabies Vaccine
(Rabipur Group)
nlelrepfbs = hkgftsswaq ckxekkftpl (pncvermgyt, wegzylzyyn - cjdvkvsock)
Phase 2
540
qnjdterqmo = osvtndjjcp zvctcnskwg (txxlbcausy, rfpdfugdow - yswjyqicbp)
-
19 Feb 2018
qnjdterqmo = syvoccgbak zvctcnskwg (txxlbcausy, yrliokhooz - qrhttnyuzj)
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Regulation

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