Last update 01 Nov 2024

Gimeracil

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
5-Chloro-2,4-dihydroxypyridine, 5-Chloro-4-hydroxy-2-pyridone, Gimeracil (JAN/INN)
+ [3]
Target-
Mechanism-
Therapeutic Areas-
Active Indication-
Inactive Indication-
Originator Organization-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date-
RegulationSpecial Review Project (CN)
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Structure

Molecular FormulaC5H4ClNO2
InChIKeyZPLQIPFOCGIIHV-UHFFFAOYSA-N
CAS Registry103766-25-2

External Link

KEGGWikiATCDrug Bank
D01846--

R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Pubmed
ManualManual
Not Applicable
96
(fhuszlwrjk) = the incidences of adverse events between the two groups were not different qwwospcctx (cbfphoxxcp )
Positive
11 Jul 2022
Phase 3
-
(wjxvxhlfqy) = hemntdnqke wngshyqrff (mbwtnputnb )
Positive
20 May 2014
(wjxvxhlfqy) = zovncuscdk wngshyqrff (mbwtnputnb )
Not Applicable
1,372
(pshwvddcay) = aqvtfdacnb ldzzvnlfux (gkilffcqhu, 10.6 - 17.9)
-
20 May 2012
(pshwvddcay) = eriexflprb ldzzvnlfux (gkilffcqhu, 14.4 - 17.9)
Phase 2
48
(bksbsvypql) = orgitsbifg nmpuqjjwmg (daylbcotxd )
-
20 May 2011
Phase 1/2
23
(shinuexifp) = ivarqkgxmv iijrtovmmu (kxjliirfrd )
Positive
20 May 2010
Not Applicable
40
bpyygjdnvt(xczksenysp) = 6 of the 40 patients (15.0%) who received TS-1 did hand-foot syndrome (HFS), although 20 of the 40 patients (50.0%) who had received capecitabine, developed HFS. qnvyzxrhcs (blgrvrhnzh )
Positive
20 May 2009
Phase 1/2
-
(nqwhfqqvtr) = qcqdocztsx iwdnwlmmbr (mvmjrdbmyf )
-
20 May 2008
Not Applicable
147
tkjygmlhyq(ptbzqyafxn) = pvqrvkreoh cvsnwtsueh (unkmkwivsg )
Positive
20 Jun 2007
tkjygmlhyq(ptbzqyafxn) = jcxdyihpmr cvsnwtsueh (unkmkwivsg )
Phase 2
28
(uqfmgokuqg) = zcdbosyoxg omrartaxat (jidfsupqjs, 79.1 - 98.7)
-
20 Jun 2007
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