Last update 05 Mar 2025

Tegafur

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-(2-Tetrahydrofuryl)-5-fluorouracil, FT, Tegafur (JP17/USAN/INN)
+ [14]
Target
Mechanism
TYMS inhibitors(Thymidylate synthase inhibitors)
Inactive Indication-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC8H9FN2O3
InChIKeyWFWLQNSHRPWKFK-UHFFFAOYSA-N
CAS Registry17902-23-7

External Link

KEGGWikiATCDrug Bank
D01244Tegafur

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Head and Neck Neoplasms
JP
28 Feb 1989
Bladder Cancer
JP
30 Apr 1986
Neoplasms
CN
01 Jan 1983
Breast Cancer
JP
10 Aug 1977
Colorectal Cancer
JP
10 Aug 1977
Stomach Cancer
JP
10 Aug 1977
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Pubmed
ManualManual
Not Applicable
96
ztkpvgdsfj(jttbruxhvv) = the incidences of adverse events between the two groups were not different rcljqkyorv (owxzxohzyu )
Positive
11 Jul 2022
Not Applicable
30
xejqbpvljt(rpjwudwuwc) = orpwlhxhlo mmmjuwryiu (wilotfobir )
Positive
22 Jul 2021
xejqbpvljt(rpjwudwuwc) = prbbsqtoeb mmmjuwryiu (wilotfobir )
Phase 2
41
qtemaatabc(etovklfsil) = Grade 3–4 adverse events: anorexia 2 (8%) ccfroaivej (wuofvqzpue )
-
01 Jun 2005
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Regulation

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