Last update 12 Dec 2024

Tegafur

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-(2-Tetrahydrofuryl)-5-fluorouracil, FT, Tegafur (JP17/USAN/INN)
+ [13]
Target
Mechanism
TYMS inhibitors(Thymidylate synthase inhibitors)
Therapeutic Areas
Active Indication
Inactive Indication
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
CN (01 Jan 1983),
Regulation-
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Structure

Molecular FormulaC8H9FN2O3
InChIKeyWFWLQNSHRPWKFK-UHFFFAOYSA-N
CAS Registry17902-23-7

External Link

KEGGWikiATCDrug Bank
D01244Tegafur

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Neoplasms
CN
01 Jan 1983
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Stomach CancerPhase 3
JP
01 Sep 2001
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Pubmed
ManualManual
Not Applicable
96
oqcliznjtg(qqblyomcie) = the incidences of adverse events between the two groups were not different aseqpcrwhg (ernzbozgmw )
Positive
11 Jul 2022
Not Applicable
30
xffgmuiovj(orhlqtusvs) = uklnjlgzmb ddzjpiuwcu (yylsbhofnf )
Positive
22 Jul 2021
xffgmuiovj(orhlqtusvs) = jjlkmqxnmu ddzjpiuwcu (yylsbhofnf )
Phase 2
41
imsxvcwlbk(jxmvoqmvtl) = Grade 3–4 adverse events: anorexia 2 (8%) zoqpjnwrsl (bhomfnclsh )
-
01 Jun 2005
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Regulation

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